CL2008002038A1 - Compounds derived from 3-phenyl-1,2-oxazole, sodium channel inhibitors; and its use for the treatment of a pain disorder. - Google Patents
Compounds derived from 3-phenyl-1,2-oxazole, sodium channel inhibitors; and its use for the treatment of a pain disorder.Info
- Publication number
- CL2008002038A1 CL2008002038A1 CL2008002038A CL2008002038A CL2008002038A1 CL 2008002038 A1 CL2008002038 A1 CL 2008002038A1 CL 2008002038 A CL2008002038 A CL 2008002038A CL 2008002038 A CL2008002038 A CL 2008002038A CL 2008002038 A1 CL2008002038 A1 CL 2008002038A1
- Authority
- CL
- Chile
- Prior art keywords
- oxazole
- phenyl
- treatment
- compounds derived
- sodium channel
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/14—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Compuestos derivados de fenil 1,2 oxazol y su uso para el tratamiento de un trastorno del dolor.Compounds derived from phenyl 1,2 oxazole and their use for the treatment of a pain disorder.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US94966507P | 2007-07-13 | 2007-07-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2008002038A1 true CL2008002038A1 (en) | 2009-07-17 |
Family
ID=39709355
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2008002038A CL2008002038A1 (en) | 2007-07-13 | 2008-07-11 | Compounds derived from 3-phenyl-1,2-oxazole, sodium channel inhibitors; and its use for the treatment of a pain disorder. |
Country Status (6)
Country | Link |
---|---|
AR (1) | AR067513A1 (en) |
CL (1) | CL2008002038A1 (en) |
PE (1) | PE20090477A1 (en) |
TW (1) | TW200911766A (en) |
UY (1) | UY31219A1 (en) |
WO (1) | WO2009010784A1 (en) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2013537180A (en) * | 2010-09-13 | 2013-09-30 | ノバルティス アーゲー | Triazine-oxadiazoles |
EP2773641B1 (en) | 2011-10-31 | 2017-09-27 | Xenon Pharmaceuticals Inc. | Biaryl ether sulfonamides and their use as therapeutic agents |
CA2853439A1 (en) | 2011-10-31 | 2013-05-10 | Xenon Pharmaceuticals Inc. | Benzenesulfonamide compounds and their use as therapeutic agents |
MX2014014234A (en) | 2012-05-22 | 2015-05-07 | Genentech Inc | N-substituted benzamides and their use in the treatment of pain. |
KR101663436B1 (en) | 2012-07-06 | 2016-10-06 | 제넨테크, 인크. | N-substituted benzamides and methods of use thereof |
KR20150131233A (en) | 2013-03-14 | 2015-11-24 | 제넨테크, 인크. | Substituted triazolopyridines and methods of use thereof |
US9493429B2 (en) | 2013-03-15 | 2016-11-15 | Genentech, Inc. | Substituted benzoxazoles and methods of use thereof |
CR20160296A (en) | 2013-11-27 | 2016-09-20 | Genentech Inc | BENZAMIDS REPLACED AND METHODS TO USE THEM |
WO2015102929A1 (en) | 2013-12-30 | 2015-07-09 | Novartis Ag | Tricyclic sulfonamide derivatives |
US10005724B2 (en) | 2014-07-07 | 2018-06-26 | Genentech, Inc. | Therapeutic compounds and methods of use thereof |
KR20180008761A (en) | 2015-05-22 | 2018-01-24 | 제넨테크, 인크. | Substituted benzamides and methods for their use |
JP2018526371A (en) | 2015-08-27 | 2018-09-13 | ジェネンテック, インコーポレイテッド | Therapeutic compounds and methods of use thereof |
RU2018115718A (en) | 2015-09-28 | 2019-10-28 | Дженентек, Инк. | THERAPEUTIC COMPOUNDS AND WAYS OF THEIR APPLICATION |
EP3380466A1 (en) | 2015-11-25 | 2018-10-03 | Genentech, Inc. | Substituted benzamides useful as sodium channel blockers |
EP3436432B1 (en) | 2016-03-30 | 2021-01-27 | Genentech, Inc. | Substituted benzamides and methods of use thereof |
MX2019004232A (en) | 2016-10-17 | 2019-08-01 | Genentech Inc | Therapeutic compounds and methods of use thereof. |
EP3601273B1 (en) | 2017-03-24 | 2021-12-01 | Genentech, Inc. | 4-piperidin-n-(pyrimidin-4-yl)chroman-7-sulfonamide derivatives as sodium channel inhibitors |
EP3759098A1 (en) | 2018-02-26 | 2021-01-06 | Genentech, Inc. | Pyridine-sulfonamide compounds and their use against pain and related conditions |
JP2021519788A (en) | 2018-03-30 | 2021-08-12 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | Condensation ring hydropyrido compound as a sodium channel inhibitor |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007075896A2 (en) * | 2005-12-22 | 2007-07-05 | Kemia, Inc. | Heterocyclic cytokine inhibitors |
-
2008
- 2008-07-09 WO PCT/GB2008/050554 patent/WO2009010784A1/en active Application Filing
- 2008-07-09 TW TW097125959A patent/TW200911766A/en unknown
- 2008-07-11 AR ARP080102987A patent/AR067513A1/en unknown
- 2008-07-11 PE PE2008001166A patent/PE20090477A1/en not_active Application Discontinuation
- 2008-07-11 CL CL2008002038A patent/CL2008002038A1/en unknown
- 2008-07-11 UY UY31219A patent/UY31219A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
PE20090477A1 (en) | 2009-05-24 |
TW200911766A (en) | 2009-03-16 |
WO2009010784A1 (en) | 2009-01-22 |
AR067513A1 (en) | 2009-10-14 |
UY31219A1 (en) | 2009-03-02 |
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