CH631169A5 - Method for preparing amides of (2-pyrimidinylthio)-alkanoic acids, having an antilipemic activity - Google Patents

Method for preparing amides of (2-pyrimidinylthio)-alkanoic acids, having an antilipemic activity Download PDF

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Publication number
CH631169A5
CH631169A5 CH317377A CH317377A CH631169A5 CH 631169 A5 CH631169 A5 CH 631169A5 CH 317377 A CH317377 A CH 317377A CH 317377 A CH317377 A CH 317377A CH 631169 A5 CH631169 A5 CH 631169A5
Authority
CH
Switzerland
Prior art keywords
pyrimidinylthio
alkyl
general formula
amides
chloro
Prior art date
Application number
CH317377A
Other languages
English (en)
Italian (it)
Inventor
Carlo Prof Scolastico
Giovanni Dr Tronconi
Original Assignee
Lpb Ist Farm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lpb Ist Farm filed Critical Lpb Ist Farm
Publication of CH631169A5 publication Critical patent/CH631169A5/it

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/38One sulfur atom

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
CH317377A 1976-03-17 1977-03-14 Method for preparing amides of (2-pyrimidinylthio)-alkanoic acids, having an antilipemic activity CH631169A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21317/76A IT1063074B (it) 1976-03-17 1976-03-17 Ammidi di acidi(z-pirimidiniltio)al canoici quali agent antilipemici

Publications (1)

Publication Number Publication Date
CH631169A5 true CH631169A5 (en) 1982-07-30

Family

ID=11180012

Family Applications (1)

Application Number Title Priority Date Filing Date
CH317377A CH631169A5 (en) 1976-03-17 1977-03-14 Method for preparing amides of (2-pyrimidinylthio)-alkanoic acids, having an antilipemic activity

Country Status (14)

Country Link
JP (1) JPS52113983A (da)
BE (1) BE852401A (da)
CA (1) CA1081230A (da)
CH (1) CH631169A5 (da)
DE (1) DE2711149C3 (da)
DK (1) DK143558C (da)
ES (1) ES456902A1 (da)
FR (1) FR2344545A1 (da)
GB (1) GB1532195A (da)
IT (1) IT1063074B (da)
MX (1) MX4818E (da)
NL (1) NL166933C (da)
PH (1) PH14865A (da)
SE (1) SE434743B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5810525Y2 (ja) * 1978-08-04 1983-02-25 三菱電機株式会社 小型電気掃除機
IT1211096B (it) * 1981-08-20 1989-09-29 Lpb Ist Farm Pirimidine e s.triazinici adattivita' ipolipidemizzante.
JPS59199673A (ja) * 1983-04-25 1984-11-12 Sumitomo Chem Co Ltd 含窒素複素環化合物、その製造法およびそれを有効成分とする有害生物防除剤
FR2636064B1 (fr) * 1988-09-08 1990-12-07 Fabre Sa Pierre Thioformamidines, leur preparation et leur application en tant que medicaments
US20030125338A1 (en) * 2001-06-12 2003-07-03 Active Pass Pharmaceuticals, Inc. Compounds, compositions and methods for modulating beta-amyloid production

Also Published As

Publication number Publication date
ES456902A1 (es) 1978-01-16
NL7702821A (nl) 1977-09-20
IT1063074B (it) 1985-02-11
NL166933C (nl) 1981-10-15
SE434743B (sv) 1984-08-13
SE7702922L (sv) 1977-09-18
DE2711149C3 (de) 1980-12-11
PH14865A (en) 1982-01-08
MX4818E (es) 1982-10-20
DK143558B (da) 1981-09-07
NL166933B (nl) 1981-05-15
DK114377A (da) 1977-09-18
FR2344545B1 (da) 1980-03-21
DK143558C (da) 1982-03-22
DE2711149A1 (de) 1977-09-29
JPS554746B2 (da) 1980-01-31
DE2711149B2 (da) 1980-04-24
JPS52113983A (en) 1977-09-24
FR2344545A1 (fr) 1977-10-14
GB1532195A (en) 1978-11-15
CA1081230A (en) 1980-07-08
BE852401A (fr) 1977-07-01

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PL Patent ceased