CH610322A5 - Process for the preparation of 1,4-benzodioxins - Google Patents
Process for the preparation of 1,4-benzodioxinsInfo
- Publication number
- CH610322A5 CH610322A5 CH1522575A CH1522575A CH610322A5 CH 610322 A5 CH610322 A5 CH 610322A5 CH 1522575 A CH1522575 A CH 1522575A CH 1522575 A CH1522575 A CH 1522575A CH 610322 A5 CH610322 A5 CH 610322A5
- Authority
- CH
- Switzerland
- Prior art keywords
- preparation
- compounds
- radical
- benzodioxins
- antibronchial
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Abstract
Compounds of formula (I) <IMAGE> in which: - n is an integer equal to 2 or 3; and - R1 and R2 each denote a C1 to C4 alkyl radical or form, jointly with the nitrogen atom to which they are bonded, a pyrrolidino, piperidino or hexamethyleneimino radical, are prepared, as well as their pharmacologically acceptable salts. A corresponding acetyl-5-hydroxy-1,4-benzodioxin is condensed with a chloroalkylamine in acetone medium and in the presence of potassium carbonate. These new compounds can be used for the preparation of medicaments for the treatment of circulatory insufficiency and of asthma and have the following pharmacological activities: vasodilatory, antibronchial- constricting, hypotensive and spasmolytic properties.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7533783A FR2330390A2 (en) | 1975-11-05 | 1975-11-05 | NEW 1,4-BENZODIOXANES, THEIR PREPARATION PROCESS AND THEIR THERAPEUTIC APPLICATION |
Publications (1)
Publication Number | Publication Date |
---|---|
CH610322A5 true CH610322A5 (en) | 1979-04-12 |
Family
ID=9162052
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH1522575A CH610322A5 (en) | 1975-11-05 | 1975-11-24 | Process for the preparation of 1,4-benzodioxins |
Country Status (14)
Country | Link |
---|---|
JP (2) | JPS5259166A (en) |
AU (1) | AU499442B2 (en) |
BE (1) | BE835828A (en) |
CA (1) | CA1065321A (en) |
CH (1) | CH610322A5 (en) |
DE (1) | DE2552868A1 (en) |
ES (1) | ES443357A1 (en) |
FR (1) | FR2330390A2 (en) |
GB (1) | GB1486356A (en) |
IT (1) | IT1059875B (en) |
LU (1) | LU73931A1 (en) |
NL (1) | NL7514416A (en) |
SE (1) | SE7513235L (en) |
SU (2) | SU586840A3 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2449088A1 (en) * | 1979-02-14 | 1980-09-12 | Delalande Sa | 5-Piperazinyl-propoxy-1,4-benzodioxan derivs. - useful as hypotensives and vasodilators |
FR2537970B1 (en) * | 1982-12-15 | 1986-08-14 | Delalande Sa | NOVEL AMINOALKOXY AROMATIC DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION IN THERAPEUTICS |
US6514996B2 (en) | 1995-05-19 | 2003-02-04 | Kyowa Hakko Kogyo Co., Ltd. | Derivatives of benzofuran or benzodioxole |
AU4967697A (en) * | 1996-11-19 | 1998-06-10 | Kyowa Hakko Kogyo Co. Ltd. | Oxygenic heterocyclic compounds |
-
1975
- 1975-11-05 FR FR7533783A patent/FR2330390A2/en active Pending
- 1975-11-21 BE BE162085A patent/BE835828A/en unknown
- 1975-11-24 CH CH1522575A patent/CH610322A5/en not_active IP Right Cessation
- 1975-11-25 GB GB48302/75A patent/GB1486356A/en not_active Expired
- 1975-11-25 DE DE19752552868 patent/DE2552868A1/en active Pending
- 1975-11-25 SE SE7513235A patent/SE7513235L/en unknown
- 1975-12-01 CA CA240,784A patent/CA1065321A/en not_active Expired
- 1975-12-04 JP JP50144905A patent/JPS5259166A/en active Pending
- 1975-12-04 LU LU73931A patent/LU73931A1/xx unknown
- 1975-12-05 AU AU87298/75A patent/AU499442B2/en not_active Expired
- 1975-12-10 NL NL7514416A patent/NL7514416A/en not_active Application Discontinuation
- 1975-12-10 ES ES443357A patent/ES443357A1/en not_active Expired
- 1975-12-18 SU SU752199290A patent/SU586840A3/en active
- 1975-12-31 IT IT70254/75A patent/IT1059875B/en active
-
1976
- 1976-01-08 JP JP51001832A patent/JPS5259167A/en active Pending
- 1976-10-25 SU SU762414459A patent/SU645576A3/en active
Also Published As
Publication number | Publication date |
---|---|
NL7514416A (en) | 1977-05-09 |
ES443357A1 (en) | 1977-05-01 |
AU499442B2 (en) | 1979-04-12 |
CA1065321A (en) | 1979-10-30 |
SU645576A3 (en) | 1979-01-30 |
BE835828A (en) | 1976-05-21 |
JPS5259166A (en) | 1977-05-16 |
AU8729875A (en) | 1977-06-09 |
FR2330390A2 (en) | 1977-06-03 |
IT1059875B (en) | 1982-06-21 |
JPS5259167A (en) | 1977-05-16 |
LU73931A1 (en) | 1976-11-11 |
DE2552868A1 (en) | 1977-05-18 |
SU586840A3 (en) | 1977-12-30 |
GB1486356A (en) | 1977-09-21 |
SE7513235L (en) | 1977-05-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PL | Patent ceased |