CH610322A5 - Process for the preparation of 1,4-benzodioxins - Google Patents

Process for the preparation of 1,4-benzodioxins

Info

Publication number
CH610322A5
CH610322A5 CH1522575A CH1522575A CH610322A5 CH 610322 A5 CH610322 A5 CH 610322A5 CH 1522575 A CH1522575 A CH 1522575A CH 1522575 A CH1522575 A CH 1522575A CH 610322 A5 CH610322 A5 CH 610322A5
Authority
CH
Switzerland
Prior art keywords
preparation
compounds
radical
benzodioxins
antibronchial
Prior art date
Application number
CH1522575A
Inventor
Claude Fauran
Guy Bourgery
Guy Raynaud
Yves Bailly
Original Assignee
Delalande Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande Sa filed Critical Delalande Sa
Publication of CH610322A5 publication Critical patent/CH610322A5/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

Compounds of formula (I) <IMAGE> in which: - n is an integer equal to 2 or 3; and - R1 and R2 each denote a C1 to C4 alkyl radical or form, jointly with the nitrogen atom to which they are bonded, a pyrrolidino, piperidino or hexamethyleneimino radical, are prepared, as well as their pharmacologically acceptable salts. A corresponding acetyl-5-hydroxy-1,4-benzodioxin is condensed with a chloroalkylamine in acetone medium and in the presence of potassium carbonate. These new compounds can be used for the preparation of medicaments for the treatment of circulatory insufficiency and of asthma and have the following pharmacological activities: vasodilatory, antibronchial- constricting, hypotensive and spasmolytic properties.
CH1522575A 1975-11-05 1975-11-24 Process for the preparation of 1,4-benzodioxins CH610322A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7533783A FR2330390A2 (en) 1975-11-05 1975-11-05 NEW 1,4-BENZODIOXANES, THEIR PREPARATION PROCESS AND THEIR THERAPEUTIC APPLICATION

Publications (1)

Publication Number Publication Date
CH610322A5 true CH610322A5 (en) 1979-04-12

Family

ID=9162052

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1522575A CH610322A5 (en) 1975-11-05 1975-11-24 Process for the preparation of 1,4-benzodioxins

Country Status (14)

Country Link
JP (2) JPS5259166A (en)
AU (1) AU499442B2 (en)
BE (1) BE835828A (en)
CA (1) CA1065321A (en)
CH (1) CH610322A5 (en)
DE (1) DE2552868A1 (en)
ES (1) ES443357A1 (en)
FR (1) FR2330390A2 (en)
GB (1) GB1486356A (en)
IT (1) IT1059875B (en)
LU (1) LU73931A1 (en)
NL (1) NL7514416A (en)
SE (1) SE7513235L (en)
SU (2) SU586840A3 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2449088A1 (en) * 1979-02-14 1980-09-12 Delalande Sa 5-Piperazinyl-propoxy-1,4-benzodioxan derivs. - useful as hypotensives and vasodilators
FR2537970B1 (en) * 1982-12-15 1986-08-14 Delalande Sa NOVEL AMINOALKOXY AROMATIC DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION IN THERAPEUTICS
US6514996B2 (en) 1995-05-19 2003-02-04 Kyowa Hakko Kogyo Co., Ltd. Derivatives of benzofuran or benzodioxole
AU4967697A (en) * 1996-11-19 1998-06-10 Kyowa Hakko Kogyo Co. Ltd. Oxygenic heterocyclic compounds

Also Published As

Publication number Publication date
NL7514416A (en) 1977-05-09
ES443357A1 (en) 1977-05-01
AU499442B2 (en) 1979-04-12
CA1065321A (en) 1979-10-30
SU645576A3 (en) 1979-01-30
BE835828A (en) 1976-05-21
JPS5259166A (en) 1977-05-16
AU8729875A (en) 1977-06-09
FR2330390A2 (en) 1977-06-03
IT1059875B (en) 1982-06-21
JPS5259167A (en) 1977-05-16
LU73931A1 (en) 1976-11-11
DE2552868A1 (en) 1977-05-18
SU586840A3 (en) 1977-12-30
GB1486356A (en) 1977-09-21
SE7513235L (en) 1977-05-06

Similar Documents

Publication Publication Date Title
ES8600264A1 (en) New furanone derivatives, process for the preparation thereof and use thereof.
IE40570L (en) Benzylamine derivatives
DE2967513D1 (en) Imidazole derivatives, process for their preparation and pharmaceutical compositions containing them
NO164351C (en) ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE 5-ALKYL-L-PHENYL-2-PIPERAZINOALKYLPYRAZOLINE-3-ON COMPOUNDS.
CH610322A5 (en) Process for the preparation of 1,4-benzodioxins
ES8504778A1 (en) Novel phenylpiperazine derivatives and process for producing the same.
ES439291A1 (en) Novel derivative of N-(3,4,5-trimethoxy cinnamoyl) piperazine, its acid addition salts, its process of preparation and its therapeutic application
ZW10781A1 (en) Novel imidazole derivatives
JPS51136676A (en) Process for preparation of carbostyril derivatives
DE3264303D1 (en) 1-furyl-3,4-dihydroisoquinolines, process for their preparation, their use and medicines containing them
DE3363802D1 (en) (2,4,6-trimethoxyphenyl)-(3-piperidinopropyl)-ketone derivatives, their therapeutical use and preparation process
SE7606497L (en) SUBSTITUTED 4-PHENYLIMIDAZOLINES, THEIR ACID ADDITINOS SALTS AND PROCEDURES FOR THE PREPARATION
JPS5212171A (en) Process for preparation of cyclohexane derivatives
JPS51125239A (en) Process for preparing new bytyrophenone derivatives
SE7713864L (en) NORTROPINE CARBAZATE DERIVATIVES AND PROCEDURES
JPS5210284A (en) Process for preparing piperazine derivatives
ES399271A1 (en) 4-tertiary-n-aminomethyl-2-methyl-2-4,6,7-trimethoxy-5-benzofuranyl- 1,3-dioxolanes their bromomethylates their process of preparation and their therapeutic application
ES8104172A1 (en) Basically substituted phenols, process for their preparation, pharmaceutical preparations containing these compounds and their use.
JPS5277045A (en) Preparation of novel indane derivatives
GB995398A (en) Novel hypotensive composition
ES485967A1 (en) A procedure for the preparation of new heterociclic derivatives of cumarina (Machine-translation by Google Translate, not legally binding)
JPS51136680A (en) Process for preparing 5-(1,2-epoxyalkyl) carbostyril derivatives.

Legal Events

Date Code Title Description
PL Patent ceased