CH598231A5 - - Google Patents

Info

Publication number
CH598231A5
CH598231A5 CH1099573A CH1099573A CH598231A5 CH 598231 A5 CH598231 A5 CH 598231A5 CH 1099573 A CH1099573 A CH 1099573A CH 1099573 A CH1099573 A CH 1099573A CH 598231 A5 CH598231 A5 CH 598231A5
Authority
CH
Switzerland
Application number
CH1099573A
Inventor
Ivan Dr Kompis
Gerald Dr Rey-Bellet
Guido Dr Zanetti
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority to CH742176A priority Critical patent/CH589065A5/en
Priority to CH742276A priority patent/CH589066A5/en
Priority to CH742376A priority patent/CH589067A5/en
Priority to CH1099573A priority patent/CH598231A5/xx
Priority to CH741976A priority patent/CH589064A5/en
Priority to DK374174AA priority patent/DK135374B/en
Priority to ZA00744512A priority patent/ZA744512B/en
Priority to US05/489,050 priority patent/US3931181A/en
Priority to FR7425210A priority patent/FR2238496B1/fr
Priority to AU71488/74A priority patent/AU482930B2/en
Priority to DE2435934A priority patent/DE2435934A1/en
Priority to GB456176A priority patent/GB1455739A/en
Priority to GB456076A priority patent/GB1455738A/en
Priority to GB3316974A priority patent/GB1455736A/en
Priority to GB455976A priority patent/GB1455737A/en
Priority to GB456276A priority patent/GB1455740A/en
Priority to JP49085239A priority patent/JPS5041876A/ja
Priority to NL7410100A priority patent/NL7410100A/en
Priority to SE7409733A priority patent/SE415975B/en
Priority to BE146980A priority patent/BE818131A/en
Priority to CA205,706A priority patent/CA1026759A/en
Priority to DK374175A priority patent/DK134549B/en
Priority to DK188376A priority patent/DK188376A/en
Publication of CH598231A5 publication Critical patent/CH598231A5/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • C07D239/49Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/38Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C07C45/515Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an acetalised, ketalised hemi-acetalised, or hemi-ketalised hydroxyl group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/281,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/301,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
CH1099573A 1973-07-27 1973-07-27 CH598231A5 (en)

Priority Applications (23)

Application Number Priority Date Filing Date Title
CH742176A CH589065A5 (en) 1973-07-27 1973-07-27 Anti-bacterial benzyl-pyrimidines - esp powerful in combination with sulphonamides
CH742276A CH589066A5 (en) 1973-07-27 1973-07-27 Anti-bacterial benzyl-pyrimidines - esp powerful in combination with sulphonamides
CH742376A CH589067A5 (en) 1973-07-27 1973-07-27 Anti-bacterial benzyl-pyrimidines - esp powerful in combination with sulphonamides
CH1099573A CH598231A5 (en) 1973-07-27 1973-07-27
CH741976A CH589064A5 (en) 1973-07-27 1974-06-21 Anti-bacterial benzyl-pyrimidines - esp powerful in combination with sulphonamides
DK374174AA DK135374B (en) 1973-07-27 1974-07-11 Analogous process for the preparation of 2,4-diamino-5-benzylpyrimidines or acid addition salts thereof.
ZA00744512A ZA744512B (en) 1973-07-27 1974-07-15 Novel benzyl pyrimidines
US05/489,050 US3931181A (en) 1973-07-27 1974-07-16 2,4-Diamino-5-benzylpyrimidines
FR7425210A FR2238496B1 (en) 1973-07-27 1974-07-19
AU71488/74A AU482930B2 (en) 1973-07-27 1974-07-22 Novel benzyl pyrimidines
DE2435934A DE2435934A1 (en) 1973-07-27 1974-07-25 NEW BENZYL PYRIMIDINE
GB456176A GB1455739A (en) 1973-07-27 1974-07-26 Acid amides
GB456076A GB1455738A (en) 1973-07-27 1974-07-26 Unsaturated nitriles
GB3316974A GB1455736A (en) 1973-07-27 1974-07-26 Benzylpyrimidine derivatives
GB455976A GB1455737A (en) 1973-07-27 1974-07-26 Acetals
GB456276A GB1455740A (en) 1973-07-27 1974-07-26 Benzylpyrimidine derivatives
JP49085239A JPS5041876A (en) 1973-07-27 1974-07-26
NL7410100A NL7410100A (en) 1973-07-27 1974-07-26 NEW BENZYLPYRIMIDINES.
SE7409733A SE415975B (en) 1973-07-27 1974-07-26 PROCEDURE FOR THE PREPARATION OF NEW BENZYLPYRIMIDINES
BE146980A BE818131A (en) 1973-07-27 1974-07-26 NEW BENZYLPYRIMIDINES
CA205,706A CA1026759A (en) 1973-07-27 1974-07-26 Benzyl pyrimidines
DK374175A DK134549B (en) 1973-07-27 1975-08-19 Analogous process for the preparation of 2,4-diamino-5-benzylpyrimidines or acid addition salts thereof.
DK188376A DK188376A (en) 1973-07-27 1976-04-27 2,4-DIAMINO-5-BENZYLPYRIMIDINES AND PREPARATIONS CONTAINING THESE COMPOUNDS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1099573A CH598231A5 (en) 1973-07-27 1973-07-27

Publications (1)

Publication Number Publication Date
CH598231A5 true CH598231A5 (en) 1978-04-28

Family

ID=4368954

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1099573A CH598231A5 (en) 1973-07-27 1973-07-27

Country Status (11)

Country Link
JP (1) JPS5041876A (en)
BE (1) BE818131A (en)
CA (1) CA1026759A (en)
CH (1) CH598231A5 (en)
DE (1) DE2435934A1 (en)
DK (1) DK135374B (en)
FR (1) FR2238496B1 (en)
GB (5) GB1455740A (en)
NL (1) NL7410100A (en)
SE (1) SE415975B (en)
ZA (1) ZA744512B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1084498A (en) 1977-05-05 1980-08-26 Alexander E. Wick Benzylpyrimidines and process for the preparation thereof
HU188588B (en) * 1982-08-13 1986-04-28 Egyt Gyogyszervegyeszeti Gyar Process for the production of 2,4-diamino-5-benzyl-pyrimidine-derivatives
EP1893603B1 (en) 2005-06-02 2009-10-14 F. Hoffmann-La Roche AG Piperidin-4-yl-amide derivatives and their use as sst receptor subtype 5 antagonists
US7855194B2 (en) 2006-03-27 2010-12-21 Hoffmann-La Roche Inc. Pyrimidine, quinazoline, pteridine and triazine derivatives

Also Published As

Publication number Publication date
DE2435934A1 (en) 1975-02-13
CA1026759A (en) 1978-02-21
FR2238496B1 (en) 1977-09-09
DK135374C (en) 1977-10-03
DK135374B (en) 1977-04-18
GB1455737A (en) 1976-11-17
BE818131A (en) 1975-01-27
NL7410100A (en) 1975-01-29
SE7409733L (en) 1975-01-28
AU7148874A (en) 1976-01-22
JPS5041876A (en) 1975-04-16
GB1455739A (en) 1976-11-17
FR2238496A1 (en) 1975-02-21
ZA744512B (en) 1975-09-24
GB1455736A (en) 1976-11-17
SE415975B (en) 1980-11-17
GB1455738A (en) 1976-11-17
DK374174A (en) 1975-04-01
GB1455740A (en) 1976-11-17

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Legal Events

Date Code Title Description
PL Patent ceased