CH505116A - 1-p-chlorobenzhydril-4-2-2-haloethoxy ethyl piperazines - Google Patents

1-p-chlorobenzhydril-4-2-2-haloethoxy ethyl piperazines

Info

Publication number
CH505116A
CH505116A CH1663166A CH1663166A CH505116A CH 505116 A CH505116 A CH 505116A CH 1663166 A CH1663166 A CH 1663166A CH 1663166 A CH1663166 A CH 1663166A CH 505116 A CH505116 A CH 505116A
Authority
CH
Switzerland
Prior art keywords
chlorobenzhydril
haloethoxy
cpds
mixt
esp
Prior art date
Application number
CH1663166A
Other languages
Italian (it)
Inventor
Roemer Elvetio Dr Pharm
Original Assignee
Crc Ricerca Chim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crc Ricerca Chim filed Critical Crc Ricerca Chim
Priority to CH1663166A priority Critical patent/CH505116A/en
Priority to ES337123A priority patent/ES337123A1/en
Priority to JP42011378A priority patent/JPS4942517B1/ja
Priority to GB870467A priority patent/GB1174819A/en
Publication of CH505116A publication Critical patent/CH505116A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

(A) Cpds. (I) X = Halogen esp. Cl. (B) Process for prepgn. cpds. (I X=OH) by hydrolysis of (I X= Halogen) with HCONH2, HCOOH and H2O mixt. esp. a 10:2:100 mixt. at reflux. (I)are psychotonic, antiallergic and antihistaminic agents. 150 g. (III Y = Cl) refluxed 18 hrs. with 10 g. (II), evapd., the residue taken up in H2O, adjusted to pH 8-9 with K2CO3 and extd. with benzene or CHCl3 gave 15.3 g. (I, X = Cl) bo.2 = 182 deg.C.
CH1663166A 1966-11-21 1966-11-21 1-p-chlorobenzhydril-4-2-2-haloethoxy ethyl piperazines CH505116A (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CH1663166A CH505116A (en) 1966-11-21 1966-11-21 1-p-chlorobenzhydril-4-2-2-haloethoxy ethyl piperazines
ES337123A ES337123A1 (en) 1966-11-21 1967-02-21 Novel Derivatives of Piperazine and Method of Preparing the same
JP42011378A JPS4942517B1 (en) 1966-11-21 1967-02-22
GB870467A GB1174819A (en) 1966-11-21 1967-02-23 Novel Derivatives of Piperazine and Method of Preparing the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1663166A CH505116A (en) 1966-11-21 1966-11-21 1-p-chlorobenzhydril-4-2-2-haloethoxy ethyl piperazines

Publications (1)

Publication Number Publication Date
CH505116A true CH505116A (en) 1971-03-31

Family

ID=4418900

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1663166A CH505116A (en) 1966-11-21 1966-11-21 1-p-chlorobenzhydril-4-2-2-haloethoxy ethyl piperazines

Country Status (4)

Country Link
JP (1) JPS4942517B1 (en)
CH (1) CH505116A (en)
ES (1) ES337123A1 (en)
GB (1) GB1174819A (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE1010095A3 (en) * 1996-04-10 1997-12-02 Ucb Sa METHOD OF PREPARATION OF ACID 2- [2- [4 - [(4-Chlorophenyl) phenylmethyl] -1-PIPERAZINYL] ETHOXY] acetic acid AND ITS SALTS.
BE1010094A3 (en) * 1996-04-10 1997-12-02 Ucb Sa NEW [2- (1-piperazinyl) ethoxy] SUBSTITUTED.
EP0919550A1 (en) * 1997-11-26 1999-06-02 Ucb, S.A. Pseudopolymorphic forms of 2-2-4-bis(4-fluorophenyl)methyl-1-piperazinyl-ethoxy acetic acid dihydrochloride

Also Published As

Publication number Publication date
JPS4942517B1 (en) 1974-11-15
GB1174819A (en) 1969-12-17
ES337123A1 (en) 1968-01-16

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Legal Events

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