CH495322A - Verfahren zur Herstellung neuartiger 3-Indenyl-aliphatischer-Amine - Google Patents
Verfahren zur Herstellung neuartiger 3-Indenyl-aliphatischer-AmineInfo
- Publication number
- CH495322A CH495322A CH1871866A CH1871866A CH495322A CH 495322 A CH495322 A CH 495322A CH 1871866 A CH1871866 A CH 1871866A CH 1871866 A CH1871866 A CH 1871866A CH 495322 A CH495322 A CH 495322A
- Authority
- CH
- Switzerland
- Prior art keywords
- indenyl
- novel
- preparation
- aliphatic amines
- amines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/657—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings
- C07C49/665—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings a keto group being part of a condensed ring system
- C07C49/67—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings a keto group being part of a condensed ring system having two rings, e.g. tetralones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/687—Unsaturated compounds containing a keto groups being part of a ring containing halogen
- C07C49/697—Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/747—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
- C07C49/755—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups a keto group being part of a condensed ring system with two or three rings, at least one ring being a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
- C07C57/60—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings having unsaturation outside the rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/72—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings and other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US51784165A | 1965-12-30 | 1965-12-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
CH495322A true CH495322A (de) | 1970-08-31 |
Family
ID=24061448
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH1871866A CH495322A (de) | 1965-12-30 | 1966-12-29 | Verfahren zur Herstellung neuartiger 3-Indenyl-aliphatischer-Amine |
Country Status (7)
Country | Link |
---|---|
US (1) | US3532752A (de) |
BR (1) | BR6685475D0 (de) |
CH (1) | CH495322A (de) |
DE (1) | DE1593133A1 (de) |
FR (2) | FR1505112A (de) |
GB (1) | GB1154506A (de) |
NL (1) | NL6618446A (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3642785A (en) * | 1969-08-11 | 1972-02-15 | Merck & Co Inc | Indenyl-3-aliphatic amines |
US3759987A (en) * | 1970-05-01 | 1973-09-18 | Merck & Co Inc | Preparation of 5-fluoro-2-methyl-1-(p-methylsulfinylbenzylidene)-3-indenyl acetic acid |
JPS5623982B2 (de) * | 1972-12-07 | 1981-06-03 | ||
US4007225A (en) * | 1973-08-11 | 1977-02-08 | Takeda Chemical Industries, Ltd. | 4-Benzoylindan-1-carboxamide and derivatives thereof |
US3998875A (en) * | 1974-10-02 | 1976-12-21 | Merck & Co., Inc. | Process of preparing 5-fluoro-2-methyl-1-(paramethylsulfinylbenzylidene)-indenyl-3-acetic acid |
JPS5740132B2 (de) * | 1975-02-19 | 1982-08-25 | ||
DE2861735D1 (en) * | 1977-08-05 | 1982-05-27 | Kabi Ab | Geminally disubstituted indene derivatives, processes for their preparation and pharmaceutical compositions containing them |
US4656190A (en) * | 1983-11-14 | 1987-04-07 | Merck & Co., Inc. | Indene derivatives and their use as PAF-antagonists |
US5001255A (en) * | 1984-12-04 | 1991-03-19 | Sandoz Pharm. Corp. | Idene analogs of mevalonolactone and derivatives thereof |
US5245028A (en) * | 1990-08-09 | 1993-09-14 | Warner-Lambert Company | Process for preparing tetracyclic amines useful as cerebrovascular agents |
US5292736A (en) * | 1993-02-26 | 1994-03-08 | Sterling Winthrop Inc. | Morpholinoalkylindenes as antiglaucoma agents |
US6214876B1 (en) * | 1994-07-21 | 2001-04-10 | Eli Lilly And Company | Indene-1-acetamide sPLA2 inhibitors |
US5998477A (en) * | 1996-06-13 | 1999-12-07 | Cell Pathways Inc. | Substituted methoxy benzylidene indenyl-acetic and propionic acids for treating patients with precancerous lesions |
US6063818A (en) * | 1996-06-13 | 2000-05-16 | Cell Pathways Inc. | Substituted benzylidene indenyl formamides, acetamides and propionamides |
US5965619A (en) * | 1996-06-13 | 1999-10-12 | Cell Pathways Inc. | Method for treating patients having precancerous lesions with substituted indene derivatives |
US6121321A (en) * | 1996-06-13 | 2000-09-19 | Cell Pathways, Inc. | Substituted methoxy benzylidene indenyl acetic and propionic acids for treating patients with precancerous lesions |
US5948779A (en) * | 1997-12-12 | 1999-09-07 | Cell Pathways, Inc. | Substituted condensation products of n-benzyl-3-indenyl acetamides with heterocyclic aldehydes |
US6028116A (en) * | 1998-04-03 | 2000-02-22 | Cell Pathways, Inc. | Substituted condensation products of 1H-indenyl-hydroxyalkanes with aldehydes for neoplasia |
ES2277828T3 (es) * | 1999-01-29 | 2007-08-01 | Osi Pharmaceuticals, Inc. | Un metodo para tratar pacientes con acne, administrando un inhibidor de pde de gmp ciclico. |
US6479493B1 (en) | 2001-08-23 | 2002-11-12 | Cell Pathways, Inc. | Methods for treatment of type I diabetes |
BR112013024525A2 (pt) * | 2011-04-01 | 2017-04-18 | Southern Res Inst | compostos, composição farmacêutica e métodos para tratar condição pré-cancerosa ou câncer em mamífero, pacientes com doença inflamatória crônica ou doença neurodegenerativa e para preparar compostos e usos de compostos e de composição farmacêutica |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2798888A (en) * | 1952-08-12 | 1957-07-09 | Ciba Pharm Prod Inc | Indene and indane compounds and their production |
US2886589A (en) * | 1957-08-05 | 1959-05-12 | Merck & Co Inc | 8-methyl-5-oxyphenyl hexahydroindan compounds |
US3072716A (en) * | 1959-03-18 | 1963-01-08 | Ciba Geigy Corp | Substituted indenes |
US3164607A (en) * | 1961-01-10 | 1965-01-05 | Upjohn Co | 2-phenyl-3-(tertiary amino alkoxy) phenyl-indenes |
NL282517A (de) * | 1961-08-31 | |||
DE1470055A1 (de) * | 1963-12-07 | 1969-07-17 | Merck Ag E | Verfahren zur Herstellung von Piperidinderivaten |
-
1965
- 1965-12-30 US US517841A patent/US3532752A/en not_active Expired - Lifetime
-
1966
- 1966-12-15 FR FR87619A patent/FR1505112A/fr not_active Expired
- 1966-12-19 BR BR185475/66A patent/BR6685475D0/pt unknown
- 1966-12-28 GB GB57942/66A patent/GB1154506A/en not_active Expired
- 1966-12-29 CH CH1871866A patent/CH495322A/de not_active IP Right Cessation
- 1966-12-29 DE DE19661593133 patent/DE1593133A1/de active Pending
- 1966-12-30 NL NL6618446A patent/NL6618446A/xx unknown
-
1967
- 1967-03-14 FR FR98737A patent/FR7139M/fr not_active Expired
Also Published As
Publication number | Publication date |
---|---|
GB1154506A (en) | 1969-06-11 |
NL6618446A (de) | 1967-07-03 |
US3532752A (en) | 1970-10-06 |
DE1593133A1 (de) | 1970-07-16 |
BR6685475D0 (pt) | 1973-12-27 |
FR7139M (de) | 1969-07-28 |
FR1505112A (fr) | 1967-12-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PL | Patent ceased |