CH433275A - Verfahren zur Herstellung von 19-Alkylsteroiden - Google Patents

Verfahren zur Herstellung von 19-Alkylsteroiden

Info

Publication number
CH433275A
CH433275A CH851363A CH851363A CH433275A CH 433275 A CH433275 A CH 433275A CH 851363 A CH851363 A CH 851363A CH 851363 A CH851363 A CH 851363A CH 433275 A CH433275 A CH 433275A
Authority
CH
Switzerland
Prior art keywords
preparation
alkyl steroids
steroids
alkyl
Prior art date
Application number
CH851363A
Other languages
English (en)
Inventor
Andor Dr Fuerst
Gerhard Dr Herzog Ernst
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority to CH851363A priority Critical patent/CH433275A/de
Priority to DE1468035A priority patent/DE1468035C3/de
Priority to NL6406879A priority patent/NL6406879A/xx
Priority to SE7677/64A priority patent/SE312554B/xx
Priority to US379709A priority patent/US3309387A/en
Priority to BR160648/64A priority patent/BR6460648D0/pt
Priority to ES301833A priority patent/ES301833A1/es
Priority to BE650260D priority patent/BE650260A/xx
Priority to FR981030A priority patent/FR1411079A/fr
Priority to DK344764AA priority patent/DK115400B/da
Priority to GB28370/64A priority patent/GB1040554A/en
Publication of CH433275A publication Critical patent/CH433275A/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
CH851363A 1963-07-09 1963-07-09 Verfahren zur Herstellung von 19-Alkylsteroiden CH433275A (de)

Priority Applications (11)

Application Number Priority Date Filing Date Title
CH851363A CH433275A (de) 1963-07-09 1963-07-09 Verfahren zur Herstellung von 19-Alkylsteroiden
DE1468035A DE1468035C3 (de) 1963-07-09 1964-06-02 Verfahren zur Herstellung von 19äthylsteroiden und die Verbindung 19äthyl-5alpha-androstan-3beta, 17betadioL
NL6406879A NL6406879A (de) 1963-07-09 1964-06-17
SE7677/64A SE312554B (de) 1963-07-09 1964-06-24
US379709A US3309387A (en) 1963-07-09 1964-07-01 19-lower alkyl androstanes and pregnanes
BR160648/64A BR6460648D0 (pt) 1963-07-09 1964-07-07 Processo para a preparacao de 19-alcoil-esteroides
ES301833A ES301833A1 (es) 1963-07-09 1964-07-08 Un procedimiento para la prepación de 19-alkil-esteroides
BE650260D BE650260A (de) 1963-07-09 1964-07-08
FR981030A FR1411079A (fr) 1963-07-09 1964-07-08 Procédé pour la préparation de 19-alcoyl-stéroïdes
DK344764AA DK115400B (da) 1963-07-09 1964-07-09 Fremgangsmåde til fremstilling af terapeutisk virksomme 3-keto-19-alkyl-androstaner.
GB28370/64A GB1040554A (en) 1963-07-09 1964-07-09 The manufacture of 3-keto-19-alkyl-steroids

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH851363A CH433275A (de) 1963-07-09 1963-07-09 Verfahren zur Herstellung von 19-Alkylsteroiden

Publications (1)

Publication Number Publication Date
CH433275A true CH433275A (de) 1967-04-15

Family

ID=4341402

Family Applications (1)

Application Number Title Priority Date Filing Date
CH851363A CH433275A (de) 1963-07-09 1963-07-09 Verfahren zur Herstellung von 19-Alkylsteroiden

Country Status (10)

Country Link
US (1) US3309387A (de)
BE (1) BE650260A (de)
BR (1) BR6460648D0 (de)
CH (1) CH433275A (de)
DE (1) DE1468035C3 (de)
DK (1) DK115400B (de)
ES (1) ES301833A1 (de)
GB (1) GB1040554A (de)
NL (1) NL6406879A (de)
SE (1) SE312554B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH464189A (de) * 1966-04-20 1968-10-31 Hoffmann La Roche Verfahren zur Herstellung von 19-Alkenylsteroiden
US3859272A (en) * 1968-07-23 1975-01-07 Hoechst Ag 19-alkylene-14- ' -hydroxy-cardenolide derivatives and process for preparing them
US4139617A (en) * 1974-05-13 1979-02-13 Richardson-Merrell Inc. 19-Oxygenated-androst-5-enes for the enhancement of libido
WO2005020928A2 (en) * 2003-08-29 2005-03-10 The Regents Of The University Of California Agents and methods for enhancing bone formation by oxysterols in combination with bone morphogenic proteins
AU2004292555A1 (en) * 2003-11-24 2005-06-09 Merck & Co., Inc. Estrogen receptor modulators
CA2569152A1 (en) * 2004-06-10 2005-12-29 Merck & Co., Inc. Estrogen receptor modulators
AU2005267210A1 (en) * 2004-06-30 2006-02-02 Merck & Co., Inc. Estrogen receptor modulators
EP1993558B1 (de) * 2006-02-27 2014-07-30 The Regents of The University of California Oxysterolverbindungen und hedgehog-weg
WO2009073186A1 (en) * 2007-12-03 2009-06-11 The Regents Of The University Of California Oxsterols for activation of hedgehog signaling, osteoinduction, antiadipogenesis, and wnt signaling
WO2013169399A1 (en) 2012-05-07 2013-11-14 The Regents Of The University Of California Oxysterol analogue oxy133 induces osteogenesis and hedgehog signaling and inhibits adipogenesis
EP2991652A4 (de) 2013-05-02 2016-12-07 Univ California Gegen knochen gerichtete knochenselektive osteogene oxysterol-wirkstoffe

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2844603A (en) * 1955-07-05 1958-07-22 Searle & Co Process for oxidation of steroids with peroxytrifluoroacetic acid
NL286295A (de) * 1961-12-04
NL292848A (de) * 1962-05-16
US3102127A (en) * 1962-06-12 1963-08-27 Syntex Corp 19-methylene-androstane derivatives
US3206458A (en) * 1962-06-12 1965-09-14 Syntex Corp 19-substituted pregnenes

Also Published As

Publication number Publication date
BR6460648D0 (pt) 1973-12-26
DK115400B (da) 1969-10-06
DE1468035A1 (de) 1968-12-12
GB1040554A (en) 1966-09-01
DE1468035C3 (de) 1974-03-21
BE650260A (de) 1965-01-08
US3309387A (en) 1967-03-14
SE312554B (de) 1969-07-21
DE1468035B2 (de) 1973-08-02
ES301833A1 (es) 1962-12-16
NL6406879A (de) 1965-01-11

Similar Documents

Publication Publication Date Title
CH463787A (de) Verfahren zur Herstellung von Polyiminolactonen
CH479595A (de) Verfahren zur Herstellung von 1-Peracylglycosyl-5-azacytosinen
CH444868A (de) Verfahren zur Herstellung von Fluoracylaziridinen
CH433275A (de) Verfahren zur Herstellung von 19-Alkylsteroiden
CH471134A (de) Verfahren zur Herstellung von Pyrazinoylbenzamidinen
CH466300A (de) Verfahren zur Herstellung von Dihydrotriazinen
CH469696A (de) Verfahren zur Herstellung von 2-Guanidino-alkylchromanen
CH488680A (de) Verfahren zur Herstellung von 16-Methylsteroiden
CH449623A (de) Verfahren zur Herstellung von 4-Alkyl-5-cyan-oxazolen
CH438286A (de) Verfahren zur Herstellung von Dibenzocycloheptadien-ketoxim-O-äthern
AT244338B (de) Verfahren zur Herstellung von 3-Amino-isoxazolen
CH440240A (de) Verfahren zur Herstellung von Fluorjodalkanen
CH466272A (de) Verfahren zur Herstellung von Cycloalkylmethylaminobenzophenonen
CH426836A (de) Verfahren zur Herstellung von Naphthindolizinchinonen
CH430716A (de) Verfahren zur Herstellung von trans-2-Phenyl-3-methylmorpholin
CH450378A (de) Verfahren zur Herstellung von B-Hydroxyäthylthiocelestosaminid
CH447211A (de) Verfahren zur Herstellung von Diaminodihydroxy-anthrachinonen
CH416106A (de) Verfahren zur Herstellung von Polydodecalactam
CH470376A (de) Verfahren zur Herstellung von 17a-Äthinyl-19-nor-testosteron
CH425809A (de) Verfahren zur Herstellung von Pyridazoniminen
CH479570A (de) Verfahren zur Herstellung von 7a-Alkyl-19-nor-steroiden
CH459973A (de) Verfahren zur Herstellung von Acetylacetamiden
CH432536A (de) Verfahren zur Herstellung von Diamino-monoazidotriazinen
AT252475B (de) Verfahren zur Herstellung von Pregnan-Derivaten
CH482664A (de) Verfahren zur Herstellung von 6-Methyl- 14-pregnenen