CH406224A - Process for the preparation of trialkoxylated derivatives of benzyl-1-piperazine - Google Patents

Process for the preparation of trialkoxylated derivatives of benzyl-1-piperazine

Info

Publication number
CH406224A
CH406224A CH697061A CH697061A CH406224A CH 406224 A CH406224 A CH 406224A CH 697061 A CH697061 A CH 697061A CH 697061 A CH697061 A CH 697061A CH 406224 A CH406224 A CH 406224A
Authority
CH
Switzerland
Prior art keywords
trialkoxylated
piperazine
benzyl
derivatives
preparation
Prior art date
Application number
CH697061A
Other languages
French (fr)
Inventor
Servier Jacques
Regnier Gilbert
Canevari Roger
Original Assignee
Science Union & Cie Societe Fr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Science Union & Cie Societe Fr filed Critical Science Union & Cie Societe Fr
Publication of CH406224A publication Critical patent/CH406224A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
CH697061A 1960-06-30 1961-06-14 Process for the preparation of trialkoxylated derivatives of benzyl-1-piperazine CH406224A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR831847A FR805M (en) 1960-06-30 1960-06-30

Publications (1)

Publication Number Publication Date
CH406224A true CH406224A (en) 1966-01-31

Family

ID=8734718

Family Applications (1)

Application Number Title Priority Date Filing Date
CH697061A CH406224A (en) 1960-06-30 1961-06-14 Process for the preparation of trialkoxylated derivatives of benzyl-1-piperazine

Country Status (5)

Country Link
BE (1) BE604839A (en)
CH (1) CH406224A (en)
ES (1) ES268523A1 (en)
FR (1) FR805M (en)
GB (1) GB929252A (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2490963B1 (en) * 1980-09-30 1986-04-18 Science Union & Cie NOVEL THERAPEUTIC COMPOSITION WITH ANTI-ISCHEMIC ACTION CONTAINING TRIMETHOXY 2, 3, 4-BENZYL 1-PIPERAZINE
JPS61161272A (en) * 1985-01-11 1986-07-21 Kanebo Ltd Novel piperazine derivative and pharmaceutical composition containing said compound as active component
FR2661176B1 (en) * 1990-04-20 1992-06-12 Adir NEW PROCESS FOR THE PREPARATION OF 1- (2,3,4-TRIMETHOXYBENZYL) PIPERAZINE IN REDUCTIVE AMINATION.
FR2703048B1 (en) * 1993-03-24 1996-01-05 Adir NOVEL N-BENZYLPIPERAZINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
FR2723944B1 (en) * 1994-08-25 1996-09-20 Adir NEW TRIMETAZIDINE SALTS AND THEIR USE IN THERAPEUTICS
FR2757164B1 (en) * 1996-12-16 1999-01-22 Adir NOVEL N-BENZYLPIPERAZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FR2805463B1 (en) * 2000-02-25 2003-01-24 Adir USE OF TRIMETAZIDINE FOR THE PRODUCTION OF PHARMACEUTICAL COMPOSITIONS FOR INHIBITING ACYL-CoA ACETYLTRANSFERASE
DE60042972D1 (en) * 2000-10-05 2009-10-29 Usv Ltd Delayed-release drug-containing trimetazidine and method of preparation
CN100413854C (en) * 2004-06-29 2008-08-27 北京德众万全药物技术开发有限公司 Simple process for preparing trimetazidine and its medicinal salts

Also Published As

Publication number Publication date
DE1445138A1 (en) 1969-02-20
BE604839A (en) 1961-10-02
FR805M (en) 1961-09-01
GB929252A (en) 1963-06-19
ES268523A1 (en) 1961-10-16

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