CA970368A - Benzodiazepine derivatives - Google Patents

Benzodiazepine derivatives

Info

Publication number: CA970368A
Authority: CA; Canada
Prior art keywords: benzodiazepine derivatives; benzodiazepine; derivatives
Prior art date: 1970-02-03
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA104,284A

Other versions

CA104284S (en

Inventor

Yoshiharu Kume

Toshiyuki Hirohashi

Mitsuhiro Akatsu

Isamu Maruyama

Kazuo Mori

Takahiro Izumi

Hisao Yamamoto

Shigeho Inaba

Kikuo Ishizumi

Michihiro Yamamoto

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Sumitomo Chemical Co Ltd

Original Assignee

Sumitomo Chemical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1970-02-03

Filing date

1971-02-02

Publication date

1975-07-01

1970-02-03 Priority claimed from JP969170A external-priority patent/JPS4910954B1/ja

1970-02-05 Priority claimed from JP1053370A external-priority patent/JPS4834600B1/ja

1970-06-24 Priority claimed from JP5553070A external-priority patent/JPS4831119B1/ja

1970-06-24 Priority claimed from JP5552970A external-priority patent/JPS4831118B1/ja

1971-02-02 Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd

1975-07-01 Application granted granted Critical

1975-07-01 Publication of CA970368A publication Critical patent/CA970368A/en

Status Expired legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
- C07D243/26—Preparation from compounds already containing the benzodiazepine skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
- C07D243/28—Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
- C07D243/30—Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
- C07D243/30—Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings
- C07D243/36—Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings containing an indole or hydrogenated indole ring system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

CA104,284A 1970-02-03 1971-02-02 Benzodiazepine derivatives Expired CA970368A (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date
JP969170A JPS4910954B1 (en)	1970-02-03	1970-02-03
JP1053370A JPS4834600B1 (en)	1970-02-05	1970-02-05
JP5553070A JPS4831119B1 (en)	1970-06-24	1970-06-24
JP5552970A JPS4831118B1 (en)	1970-06-24	1970-06-24

Publications (1)

Publication Number	Publication Date
CA970368A true CA970368A (en)	1975-07-01

Family

ID=27455232

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA104,284A Expired CA970368A (en)	1970-02-03	1971-02-02	Benzodiazepine derivatives

Country Status (13)

Country	Link
BE (1)	BE762404A (en)
CA (1)	CA970368A (en)
CH (3)	CH549033A (en)
DE (1)	DE2166473A1 (en)
DK (1)	DK134018B (en)
FI (1)	FI52081C (en)
FR (1)	FR2081482B1 (en)
GB (1)	GB1309948A (en)
IL (1)	IL36121A (en)
NL (1)	NL169072C (en)
NO (1)	NO131031C (en)
PL (1)	PL70900B1 (en)
SE (1)	SE364714B (en)

1971
- 1971-01-06 CH CH1648473A patent/CH549033A/en not_active IP Right Cessation
- 1971-01-27 DK DK35571AA patent/DK134018B/en not_active IP Right Cessation
- 1971-01-28 NO NO300/71A patent/NO131031C/no unknown
- 1971-01-28 FI FI710234A patent/FI52081C/en active
- 1971-01-29 FR FR7103060A patent/FR2081482B1/fr not_active Expired
- 1971-02-01 DE DE19712166473 patent/DE2166473A1/en active Pending
- 1971-02-01 CH CH144371A patent/CH578543A5/xx not_active IP Right Cessation
- 1971-02-01 CH CH1089574A patent/CH581632A5/xx not_active IP Right Cessation
- 1971-02-02 IL IL36121A patent/IL36121A/en unknown
- 1971-02-02 SE SE01297/71A patent/SE364714B/xx unknown
- 1971-02-02 PL PL1971145964A patent/PL70900B1/en unknown
- 1971-02-02 BE BE762404A patent/BE762404A/en not_active IP Right Cessation
- 1971-02-02 CA CA104,284A patent/CA970368A/en not_active Expired
- 1971-02-02 NL NLAANVRAGE7101382,A patent/NL169072C/en not_active IP Right Cessation
- 1971-04-19 GB GB2082771A patent/GB1309948A/en not_active Expired

Also Published As

Publication number	Publication date
DK134018B (en)	1976-08-30
NO131031C (en)	1975-03-25
CH549033A (en)	1974-05-15
NO131031B (en)	1974-12-16
CH578543A5 (en)	1976-08-13
FR2081482B1 (en)	1975-10-10
NL7101382A (en)	1971-08-05
NL169072C (en)	1982-06-01
FI52081B (en)	1977-02-28
GB1309948A (en)	1973-03-14
IL36121A0 (en)	1971-04-28
DE2104571A1 (en)	1971-08-05
SE364714B (en)	1974-03-04
CH581632A5 (en)	1976-11-15
FR2081482A1 (en)	1971-12-03
BE762404A (en)	1971-07-16
FI52081C (en)	1977-06-10
NL169072B (en)	1982-01-04
DE2166473A1 (en)	1974-02-21
IL36121A (en)	1975-08-31
DE2104571B2 (en)	1976-03-04
DK134018C (en)	1977-01-31
PL70900B1 (en)	1974-04-30

Publication	Publication Date	Title
AU462319B2 (en)	1975-06-19	Azepine derivatives
CA972754A (en)	1975-08-12	Benzodiazepine derivatives
CA922317A (en)	1973-03-06	Benzodiazepine derivatives
CA933520A (en)	1973-09-11	Benzodiazepine derivatives
MY7400128A (en)	1974-12-31	Benzodiazepine derivatives
CA955250A (en)	1974-09-24	Benzodiazepine derivatives
AU461577B2 (en)	1975-05-29	Benzodiazepine derivatives
AU458983B2 (en)	1975-03-13	Benzodiazepine derivatives
CA952905A (en)	1974-08-13	Benzodiazepine derivatives
AU3286971A (en)	1973-03-08	Benzodiazepine derivatives
AU448106B2 (en)	1972-08-17	Benzodiazepine derivatives
CA970368A (en)	1975-07-01	Benzodiazepine derivatives
AU458903B2 (en)	1975-02-19	Benzodiazepine derivatives
AU458358B2 (en)	1972-10-12	Benzodiazepine derivatives
AU458359B2 (en)	1972-10-12	Benzodiazepine derivatives
AU456904B2 (en)	1972-05-25	Benzodiazepine derivatives
AU456741B2 (en)	1972-07-27	Benzodiazepine derivatives
AU452522B2 (en)	1974-08-22	Benzodiazepine derivatives
CA946385A (en)	1974-04-30	Benzodiazepine derivatives
CA947289A (en)	1974-05-14	Benzodiazepine derivatives
CA975772A (en)	1975-10-07	Benzodiazepine derivatives
CA948190A (en)	1974-05-28	Benzodiazepine derivatives
CA954513A (en)	1974-09-10	Benzodiazepine derivatives
AU463907B2 (en)	1975-08-07	Benzodiazepines
AU448959B2 (en)	1972-08-03	Novel benzodiazepine derivatives