CA957364A - Preparation of polar-substituted phenyl propanolamines - Google Patents

Preparation of polar-substituted phenyl propanolamines

Info

Publication number
CA957364A
CA957364A CA067,618A CA67618A CA957364A CA 957364 A CA957364 A CA 957364A CA 67618 A CA67618 A CA 67618A CA 957364 A CA957364 A CA 957364A
Authority
CA
Canada
Prior art keywords
propanolamines
polar
preparation
substituted phenyl
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA067,618A
Other languages
English (en)
Inventor
Joachim Augstein
Michael Snarey
Allan L. Ham
Peter R. Leeming
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp
Original Assignee
Pfizer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB28492/69A external-priority patent/GB1245148A/en
Application filed by Pfizer Corp filed Critical Pfizer Corp
Application granted granted Critical
Publication of CA957364A publication Critical patent/CA957364A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/24—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
    • C07C243/38—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D263/06—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA067,618A 1968-11-18 1969-11-17 Preparation of polar-substituted phenyl propanolamines Expired CA957364A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB5453468 1968-11-18
GB28492/69A GB1245148A (en) 1968-11-18 1968-11-18 Propanolamine derivatives

Publications (1)

Publication Number Publication Date
CA957364A true CA957364A (en) 1974-11-05

Family

ID=26259405

Family Applications (1)

Application Number Title Priority Date Filing Date
CA067,618A Expired CA957364A (en) 1968-11-18 1969-11-17 Preparation of polar-substituted phenyl propanolamines

Country Status (9)

Country Link
US (1) US3723524A (de)
JP (1) JPS501012B1 (de)
BE (1) BE741762A (de)
CA (1) CA957364A (de)
CH (1) CH522588A (de)
DE (1) DE1957706C3 (de)
ES (1) ES373606A1 (de)
FR (1) FR2023556B1 (de)
SE (1) SE368197B (de)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4086272A (en) * 1970-07-18 1978-04-25 Pfizer Inc. Phenyl-alkanolamine, alkylamine and alpha-aminoalkyl ketone derivatives as heart stimulants
LU66207A1 (de) * 1972-09-29 1974-04-02
GB1398738A (en) * 1972-12-05 1975-06-25 Pfizer Ltd Propanolamine derivatives
DE2309887C2 (de) * 1973-02-28 1983-11-10 C.H. Boehringer Sohn, 6507 Ingelheim 1-Aryloxy-2-hydroxy-3-alkinylaminopropan-Derivate und deren physiologisch verträgliche Säureadditionssalze, pharmazeutische Präparate und Herstellungsverfahren für die Verbindungen
US4041074A (en) * 1973-07-19 1977-08-09 Imperial Chemical Industries Limited 1-Hydroxyaryl-2-amidoalkylaminoethanol derivatives
GB1413911A (en) * 1973-08-18 1975-11-12 Pfizer Ltd Preparation of propanolamine derivatives
US4041075A (en) * 1973-12-12 1977-08-09 Imperial Chemical Industries Limited Phenoxy-alkanolamine derivatives
HU169464B (de) * 1974-02-20 1976-11-28
US3911007A (en) * 1974-08-08 1975-10-07 Searle & Co N-substituted N-benzyloxy-2-methyl-2-(4-halophenoxy)propionamides
FR2285859A1 (fr) * 1974-09-30 1976-04-23 Lafon Labor Phenylsulfinyl-amidines et derives
US4165384A (en) * 1974-11-01 1979-08-21 Aktiebolaget Hassle Amide substituted phenoxy propanol amines
US4152446A (en) * 1974-11-16 1979-05-01 Boehringer Mannheim Gmbh Aminopropanol compounds and compositions for the treatment of cardiac and circulatory diseases
US4151297A (en) * 1977-10-31 1979-04-24 Syntex (U.S.A.) Inc. Bicyclo [3.1.0] hexyl-substituted ethylamino carbonyl phenoxy cardiovascular agents
US4145443A (en) * 1977-10-31 1979-03-20 Syntex (U.S.A.) Inc. Bicyclo 3.1.0!hexylethylaminocarbonyl-substituted naphthyloxy cardiovascular agents
DD146749A3 (de) 1977-12-01 1981-03-04 Dieter Lehmann Verfahren zur herstellung von phenoxyalkanolamin-derivaten
US4163053A (en) * 1977-12-27 1979-07-31 Schering Corporation Anti-hypertensive 5-[2-(substituted anilinoalkylamino)-1-hydroxyalkyl]salicylamides
DE2805404A1 (de) * 1978-02-09 1979-08-16 Merck Patent Gmbh 1-aryloxy-3-nitratoalkylamino-2-propanole und verfahren zu ihrer herstellung
US4391826A (en) * 1978-07-03 1983-07-05 Eli Lilly And Company Phenethanolamines, compositions containing the same, and method for effecting weight control
US4845127A (en) * 1978-07-03 1989-07-04 Eli Lilly And Company Phenethanolamines, compositions containing the same and method for effecting weight control
DD150456A5 (de) * 1979-03-01 1981-09-02 Ciba Geigy Ag Verfahren zur herstellung von derivaten des 3-amino-1,2-propandiols
EP0028105B1 (de) * 1979-10-25 1983-01-19 Beecham Group Plc Sekundäre Amine, ihre Herstellung und Verwendung in pharmazeutischen Zusammensetzungen
US4558156A (en) * 1980-02-08 1985-12-10 Yamanouchi Pharmaceutical Co., Ltd. Sulfamoyl-substituted phenethylamine derivatives
JPS56110665A (en) * 1980-02-08 1981-09-01 Yamanouchi Pharmaceut Co Ltd Sulfamoyl-substituted phenetylamine derivative and its preparation
DE3162756D1 (en) * 1980-05-22 1984-04-26 Beecham Group Plc Arylethanolamine derivatives, their preparation and use in pharmaceutical compositions
US4410548A (en) * 1980-07-09 1983-10-18 Reckitt & Colman Products Limited Propanolamine derivatives
DE3125870C2 (de) * 1980-07-09 1994-09-15 William John Louis 3-Aminopropoxyphenyl Derivate, ihre Herstellung und sie enthaltende Arzneimittel
DE3048487A1 (de) * 1980-12-22 1982-07-29 Cassella Ag, 6000 Frankfurt Basisch substituierte pyridazine, ihre herstellung und ihre verwendung
US4554282A (en) * 1981-02-26 1985-11-19 Warner-Lambert Company Substituted 2,2-dimethyl-5-phenoxypentanoic acid benzamides as anti-arteriosclerotic agents and method
EP0097000B1 (de) * 1982-06-10 1987-09-09 Beecham Wuelfing GmbH & Co KG Amine-Derivate, diese enthaltende Zusammenstellungen und Verfahren zu ihrer Herstellung
US4599333A (en) * 1982-06-14 1986-07-08 Teikoku Hormone Mfg. Co., Ltd. Hydrazinopyridazine compound, process for production thereof, and use thereof as medicament
US4556668A (en) * 1983-07-15 1985-12-03 American Hospital Supply Corporation Ethylenediamine derivatives of aryloxypropanolamine aryl esters having various medicinal properties
US5166218A (en) * 1983-10-19 1992-11-24 Hoffmann-La Roche Inc. Phenoxypropanolamines and pharmaceutical compositions thereof
CA1262729A (en) * 1983-10-19 1989-11-07 Leo Alig Phenoxypropanolamines
EP0151513A1 (de) * 1984-01-12 1985-08-14 Eli Lilly And Company Inotropische Mittel
DE3428525A1 (de) * 1984-08-02 1986-02-13 Boehringer Mannheim Gmbh, 6800 Mannheim Verwendung von alkylendiamin-derivaten zur behandlung von durchblutungsstoerungen sowie arzneimittel, die diese verbindung enthalten
GB8519154D0 (en) * 1985-07-30 1985-09-04 Ici Plc Aromatic ethers
JPS6341451A (ja) * 1986-08-06 1988-02-22 Nippon Kayaku Co Ltd エ−テル誘導体およびそれを有効成分とする殺ダニ、殺虫組成物
DE3866984D1 (en) * 1987-07-21 1992-01-30 Hoffmann La Roche Phenoxypropanolamine.
GB8925032D0 (en) * 1989-11-06 1989-12-28 Ici Plc Chemical compounds
US5491134A (en) * 1994-09-16 1996-02-13 Bristol-Myers Squibb Company Sulfonic, phosphonic or phosphiniic acid β3 agonist derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB902617A (en) * 1959-04-22 1962-08-01 Pfizer Ltd Improvements in or relating to therapeutically-active alkylamines
NL301580A (de) * 1962-12-11
GB1128052A (en) * 1965-06-08 1968-09-25 Ici Ltd Alkanolamine derivatives
GB1078852A (en) * 1964-09-30 1967-08-09 Ici Ltd Alkanolamine derivatives
GB1199632A (en) * 1967-09-07 1970-07-22 Ici Ltd Alkanolamine Derivatives
GB1200886A (en) * 1966-09-23 1970-08-05 Allen & Hanburys Ltd Phenylaminoethanol derivatives
GB1285038A (en) * 1969-02-21 1972-08-09 Ici Ltd Alkanolamine derivatives

Also Published As

Publication number Publication date
JPS501012B1 (de) 1975-01-14
DE1957706C3 (de) 1978-06-29
DE1957706B2 (de) 1977-11-03
ES373606A1 (es) 1972-06-01
CH522588A (fr) 1972-06-30
FR2023556A1 (de) 1970-08-21
US3723524A (en) 1973-03-27
DE1957706A1 (de) 1970-05-27
BE741762A (de) 1970-05-19
FR2023556B1 (de) 1974-05-24
SE368197B (de) 1974-06-24

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