CA956939A - Epipodophyllotoxin compounds - Google Patents

Epipodophyllotoxin compounds

Info

Publication number: CA956939A
Authority: CA; Canada
Prior art keywords: epipodophyllotoxin; compounds; epipodophyllotoxin compounds
Prior art date: 1968-02-27
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA043,890A

Other versions

CA43890S (en

Inventor

Max Kuhn

Camilla Keller-Juslen

Jany Renz

Albert Von Wartburg

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Sandoz Patent Ltd

Original Assignee

Sandoz Patent Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1968-02-27

Filing date

1969-02-25

Publication date

1974-10-29

1969-02-25 Application filed by Sandoz Patent Ltd filed Critical Sandoz Patent Ltd

1974-10-29 Application granted granted Critical

1974-10-29 Publication of CA956939A publication Critical patent/CA956939A/en

Status Expired legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/54—Preparation of carboxylic acid anhydrides
- C07C51/56—Preparation of carboxylic acid anhydrides from organic acids, their salts, their esters or their halides, e.g. by carboxylation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

CA043,890A 1968-02-27 1969-02-25 Epipodophyllotoxin compounds Expired CA956939A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH284568A CH514578A (en)	1968-02-27	1968-02-27	Process for the production of glucosides

Publications (1)

Publication Number	Publication Date
CA956939A true CA956939A (en)	1974-10-29

Family

ID=4242875

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA043,890A Expired CA956939A (en)	1968-02-27	1969-02-25	Epipodophyllotoxin compounds

Country Status (9)

Country	Link
AT (2)	AT319971B (en)
BR (1)	BR6906655D0 (en)
CA (1)	CA956939A (en)
CH (2)	CH514578A (en)
CS (2)	CS153033B2 (en)
DK (2)	DK123715B (en)
FI (1)	FI48924C (en)
NL (1)	NL166028C (en)
SU (1)	SU406346A3 (en)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4935504A (en) *	1987-12-18	1990-06-19	Bristol-Myers Company	Epipodophyllotoxin glucoside 4'-acyl derivatives
US5036055A (en) *	1989-06-07	1991-07-30	Bristol-Myers Company	Acylated derivatives of etoposide
US5066645A (en) *	1989-09-01	1991-11-19	Bristol-Myers Company	Epipodophyllotoxin altroside derivatives
US5463040A (en) *	1994-06-28	1995-10-31	Teva Pharmaceutical Industries, Ltd.	Method of preparing etoposide
US8551973B2 (en)	2008-12-23	2013-10-08	Gilead Pharmasset Llc	Nucleoside analogs
US8716263B2 (en)	2008-12-23	2014-05-06	Gilead Pharmasset Llc	Synthesis of purine nucleosides
US8716262B2 (en)	2008-12-23	2014-05-06	Gilead Pharmasset Llc	Nucleoside phosphoramidates
US8759510B2 (en)	2008-06-11	2014-06-24	Gilead Pharmasset Llc	Nucleoside cyclicphosphates
US8859756B2 (en)	2010-03-31	2014-10-14	Gilead Pharmasset Llc	Stereoselective synthesis of phosphorus containing actives
US10265279B2 (en)	2016-03-15	2019-04-23	Oryzon Genomics, S.A.	Combinations of LSD1 inhibitors for use in the treatment of solid tumors

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0111058B1 (en) *	1982-11-26	1987-11-04	Nippon Kayaku Kabushiki Kaisha	Process for producing 4'-demethyl-epipodophyllotoxin-beta-d-ethylidene-glucoside and acyl-derivative thereof
JPS61189230A (en) *	1985-02-19	1986-08-22	Nippon Kayaku Co Ltd	Etoposide preparation
IL77334A (en) *	1985-12-16	1991-04-15	Univ Bar Ilan	Synthesis of 9-epipodophyllotoxin glucoside derivatives and some novel intermediates therefor
US4904768A (en) *	1987-08-04	1990-02-27	Bristol-Myers Company	Epipodophyllotoxin glucoside 4'-phosphate derivatives

1968
- 1968-02-27 CH CH284568A patent/CH514578A/en not_active IP Right Cessation
1969
- 1969-01-31 NL NL6901619.A patent/NL166028C/en not_active IP Right Cessation
- 1969-02-06 DK DK64169AA patent/DK123715B/en not_active IP Right Cessation
- 1969-02-06 FI FI690368A patent/FI48924C/en active
- 1969-02-25 AT AT128571A patent/AT319971B/en not_active IP Right Cessation
- 1969-02-25 CS CS526269*A patent/CS153033B2/cs unknown
- 1969-02-25 SU SU1306929A patent/SU406346A3/ru active
- 1969-02-25 CA CA043,890A patent/CA956939A/en not_active Expired
- 1969-02-25 CS CS132569A patent/CS153032B2/cs unknown
- 1969-02-25 AT AT188969A patent/AT303270B/en not_active IP Right Cessation
- 1969-02-26 BR BR206655/69A patent/BR6906655D0/en unknown
1970
- 1970-10-08 CH CH1489370A patent/CH518927A/en not_active IP Right Cessation
1971
- 1971-06-01 DK DK266771AA patent/DK128563B/en not_active IP Right Cessation

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4935504A (en) *	1987-12-18	1990-06-19	Bristol-Myers Company	Epipodophyllotoxin glucoside 4'-acyl derivatives
US5036055A (en) *	1989-06-07	1991-07-30	Bristol-Myers Company	Acylated derivatives of etoposide
US5066645A (en) *	1989-09-01	1991-11-19	Bristol-Myers Company	Epipodophyllotoxin altroside derivatives
US5463040A (en) *	1994-06-28	1995-10-31	Teva Pharmaceutical Industries, Ltd.	Method of preparing etoposide
US8759510B2 (en)	2008-06-11	2014-06-24	Gilead Pharmasset Llc	Nucleoside cyclicphosphates
US8551973B2 (en)	2008-12-23	2013-10-08	Gilead Pharmasset Llc	Nucleoside analogs
US8716263B2 (en)	2008-12-23	2014-05-06	Gilead Pharmasset Llc	Synthesis of purine nucleosides
US8716262B2 (en)	2008-12-23	2014-05-06	Gilead Pharmasset Llc	Nucleoside phosphoramidates
US8957045B2 (en)	2008-12-23	2015-02-17	Gilead Pharmasset Llc	Nucleoside phosphoramidates
US9045520B2 (en)	2008-12-23	2015-06-02	Gilead Pharmasset Llc	Synthesis of purine nucleosides
US8859756B2 (en)	2010-03-31	2014-10-14	Gilead Pharmasset Llc	Stereoselective synthesis of phosphorus containing actives
US10265279B2 (en)	2016-03-15	2019-04-23	Oryzon Genomics, S.A.	Combinations of LSD1 inhibitors for use in the treatment of solid tumors

Also Published As

Publication number	Publication date
NL166028B (en)	1981-01-15
DK128563B (en)	1974-05-27
SU406346A3 (en)	1973-11-05
CS153033B2 (en)	1974-02-22
BR6906655D0 (en)	1973-01-09
CH518927A (en)	1972-02-15
DK123715B (en)	1972-07-24
AT303270B (en)	1972-11-27
FI48924B (en)	1974-10-31
FI48924C (en)	1975-02-10
AT319971B (en)	1975-01-27
NL166028C (en)	1981-06-15
CS153032B2 (en)	1974-02-22
NL6901619A (en)	1969-08-29
CH514578A (en)	1971-10-31
SU447886A3 (en)	1974-10-25

Publication	Publication Date	Title
CA956939A (en)	1974-10-29	Epipodophyllotoxin compounds
CA948971A (en)	1974-06-11	Complex compounds
AU423886B2 (en)	1972-05-05	Croplifter
CA797586A (en)	1968-10-29	Roues de vehicules
CA787938A (en)	1968-06-18	Aminoalkyliminodibenzyl compounds
CA790076A (en)	1968-07-16	Phenylalanine-type compounds
CA798362A (en)	1968-11-05	Propanepolyphosphonate compounds
CA797850A (en)	1968-10-29	N-allyl-4-phenyl-piperidine compounds
CA776707A (en)	1968-01-23	Phosphato-phosphorus compounds
CA790075A (en)	1968-07-16	Phenylalanine-type compounds
CA789551A (en)	1968-07-09	Quinolylbenzothiazole compounds
CA781926A (en)	1968-04-02	Azolyl-thiophene compounds
CA971966A (en)	1975-07-29	N-arylaminoethyl-4-pyridine compounds
CA778399A (en)	1968-02-13	Vinyllead compounds
CA921034A (en)	1973-02-13	Dithiobisheterocyclic compounds
CA799975A (en)	1968-11-26	Nitrothenylideneamino compounds
CA789048A (en)	1968-07-02	Vinylphosphorus compounds
CA802240A (en)	1968-12-24	Polycycloalkene compounds
CA802906A (en)	1968-12-31	1-cyclopropylmethyl-4-phenylpiperidine compounds
CA786353A (en)	1968-05-28	Phenylalanine-type compounds
CA790936A (en)	1968-07-30	Enveloppes de pneumatiques
CA790384A (en)	1968-07-23	Enveloppes de pneumatiques
CA793624A (en)	1968-09-03	Enveloppes de pneumatiques
AU441680B2 (en)	1973-10-18	Improved cork-wire
CA938298A (en)	1973-12-11	Epithio compounds