CA945167A - 1,4-dihydropyridines and their production - Google Patents

1,4-dihydropyridines and their production

Info

Publication number
CA945167A
CA945167A CA103,180A CA103180A CA945167A CA 945167 A CA945167 A CA 945167A CA 103180 A CA103180 A CA 103180A CA 945167 A CA945167 A CA 945167A
Authority
CA
Canada
Prior art keywords
dihydropyridines
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA103,180A
Inventor
Friedrich Bossert
Wulf Vater
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Application granted granted Critical
Publication of CA945167A publication Critical patent/CA945167A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
CA103,180A 1970-01-24 1971-01-20 1,4-dihydropyridines and their production Expired CA945167A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702003146 DE2003146A1 (en) 1970-01-24 1970-01-24 New 1,4-dihydropyridine derivatives

Publications (1)

Publication Number Publication Date
CA945167A true CA945167A (en) 1974-04-09

Family

ID=5760409

Family Applications (1)

Application Number Title Priority Date Filing Date
CA103,180A Expired CA945167A (en) 1970-01-24 1971-01-20 1,4-dihydropyridines and their production

Country Status (15)

Country Link
US (1) US3775422A (en)
AT (2) AT304552B (en)
BE (1) BE761929A (en)
CA (1) CA945167A (en)
CH (1) CH586200A5 (en)
CS (2) CS163747B2 (en)
DE (1) DE2003146A1 (en)
ES (1) ES387562A1 (en)
FR (1) FR2081452B1 (en)
GB (1) GB1317425A (en)
HU (1) HU162199B (en)
IE (1) IE34890B1 (en)
IL (1) IL35924A (en)
NL (1) NL7100816A (en)
ZA (1) ZA7152B (en)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1430961A (en) * 1972-01-22 1976-04-07 Yamanouchi Pharma Co Ltd 1-substituted-1,4-dihyddrypyridine derivatives
US3985886A (en) * 1972-03-06 1976-10-12 Bayer Aktiengesellschaft 2-Amino-4,5-dihydropyridine derivatives and process for their preparation
US4001258A (en) * 1972-03-06 1977-01-04 Bayer Aktiengesellschaft 2-amino-1,4-dihydropyridine derivatives
US3917622A (en) * 1972-03-06 1975-11-04 Bayer Ag 2-Amino-1,4-dihydropyridine derivatives
DE2210674C3 (en) * 1972-03-06 1981-09-24 Bayer Ag, 5090 Leverkusen 2-Amino-6-methyl-1,4-dihydropyridines, process for their preparation and pharmaceuticals containing them
US3988458A (en) * 1972-03-06 1976-10-26 Bayer Aktiengesellschaft Bicyclic derivatives of 1,4-dihydropyridine 3,5-carboxylic acid esters
US3887558A (en) * 1972-03-06 1975-06-03 Bayer Ag Process for producing 2,6-diamino -1,4- dihydro-3,5-pyridine-dicarboxylates and derivatives thereof
US3935223A (en) * 1972-03-06 1976-01-27 Bayer Aktiengesellschaft 2-Amino-1,4-dihydropyridine derivatives
US3917620A (en) * 1972-03-06 1975-11-04 Bayer Ag 2-Amino-4,5-dihydropyridine derivatives
US3992545A (en) * 1972-03-06 1976-11-16 Bayer Aktiengesellschaft 2-Amino-4,5-dihydropyridine derivatives in pharmaceutical compositions
US3917619A (en) * 1972-03-06 1975-11-04 Bayer Ag 2-Amino-4,5-dihydropyridine derivatives
US3957998A (en) * 1972-03-06 1976-05-18 Bayer Aktiengesellschaft Use of 2,6-diamino-4-substituted-1,4-dihydropyridine-3,5-dicarboxylic acid esters for effecting coronary vessel dilation and treating hypertension
US3857849A (en) * 1973-02-28 1974-12-31 Bayer Ag 2-amino-1,4-dihydropyridine derivatives
DD106832A5 (en) * 1972-03-06 1974-07-05
US3939171A (en) * 1972-03-06 1976-02-17 Bayer Aktiengesellschaft 2-Amino-1,4-dihydropyridine derivatives
US3968117A (en) * 1972-06-10 1976-07-06 Bayer Aktiengesellschaft 1,4-Dihydropyridines
DE2228363A1 (en) * 1972-06-10 1974-01-03 Bayer Ag 1,4-DIHYDROPYRIDINE, METHOD FOR MANUFACTURING AND USE AS A MEDICINAL PRODUCT
DE2242786A1 (en) * 1972-08-31 1974-03-14 Bayer Ag PROCESS FOR THE MANUFACTURING OF NEW 2-AMINO-1,4-DIHYDROPYRIDINES WITH A CARBONYL FUNCTION AND THEIR USE AS A MEDICINAL PRODUCT
DE2242787C2 (en) * 1972-08-31 1982-01-21 Bayer Ag, 5090 Leverkusen 4-Phenyl-6-amino-3,4-dihydropyridon- (2) -3,5-dicarboxylic acid diethyl ester derivatives, a process for their preparation and pharmaceuticals containing them
US3989708A (en) * 1972-08-31 1976-11-02 Bayer Aktiengesellschaft 2-Amino-1,4-dihydropyridine derivatives
GB1409865A (en) * 1973-02-13 1975-10-15 Science Union & Cie Dihydropyridines derivatives their preparation and pharmaceu tical compositions containing them
US4002762A (en) * 1973-03-03 1977-01-11 Bayer Aktiengesellschaft 2-Amino-3,4-dihydropyridines used to effect coronary vessel dilation and treat hypertension
FR2320750A1 (en) * 1975-08-12 1977-03-11 Hexachimie 1,4-DIHYDRO PYRIDINES AND THEIR THERAPEUTIC APPLICATION
DE3021958A1 (en) * 1980-06-12 1981-12-24 Bayer Ag, 5090 Leverkusen 1,4-DIHYDROPYRIDINE, METHOD FOR THE PRODUCTION THEREOF AND THE MEDICINAL PRODUCTS CONTAINING THEM
US4497808A (en) * 1981-12-30 1985-02-05 Ciba-Geigy Corporation N-Oxide compounds useful in the treatment of cardiovascular ailments
US4529733A (en) * 1983-04-06 1985-07-16 Merrell Dow Pharmaceuticals Inc. Antihypertensive 3-furoyl-1,4-dihydropyridines
IE57810B1 (en) * 1984-03-27 1993-04-21 Delagrange Lab 1,4-dihydropyridine derivatives,their preparation and their use
US4994476A (en) * 1984-10-31 1991-02-19 Bristol-Myers Company Dihydropyridin-3,5-dicarboxylates incorporating aryloxypropanolamine moieties
JPS6289662A (en) * 1985-06-14 1987-04-24 Sankyo Co Ltd 1,4-dihydropyridine derivative
US4772596A (en) * 1986-10-09 1988-09-20 Sankyo Company Limited Dihydropyridine derivatives, their preparation and their use
DE4118707A1 (en) * 1991-06-07 1992-12-10 Bayer Ag PHARMACEUTICAL USE OF 3-FORMYL-1,4-DIHYDROPYRIDINES, NEW COMPOUNDS AND METHOD OF PREPARING THEM
DE102005034264A1 (en) 2005-07-22 2007-02-01 Bayer Healthcare Ag 4-Chromenonyl-1,4-dihydropyridinecarbonitriles and their use
DE102005034267A1 (en) 2005-07-22 2007-01-25 Bayer Healthcare Ag New 4-chromenonyl-1,4-dihydropyridine derivatives, useful for treatment of e.g. aldosteronism, hypertension and cardiac insufficiency, are antagonists of the mineralcorticoid receptor
WO2013178821A1 (en) * 2012-06-01 2013-12-05 Leibniz-Institut für Altersforschung - Fritz-Lipmann-Institut e.V. (FLI) Inhibitors of the notch signalling pathway and secretion for use in medicine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3455939A (en) * 1967-06-07 1969-07-15 Smithkline Corp 4-(4-chloro-3-sulfamoylphenyl)-1,4-dihydropyridines

Also Published As

Publication number Publication date
AT306720B (en) 1973-04-25
IL35924A (en) 1974-09-10
CH586200A5 (en) 1977-03-31
AT304552B (en) 1973-01-10
ZA7152B (en) 1971-10-27
NL7100816A (en) 1971-07-27
US3775422A (en) 1973-11-27
IL35924A0 (en) 1971-02-25
FR2081452A1 (en) 1971-12-03
HU162199B (en) 1973-01-29
SU383290A3 (en) 1973-05-25
BE761929A (en) 1971-07-22
IE34890L (en) 1971-07-24
DE2003146A1 (en) 1971-07-29
FR2081452B1 (en) 1974-08-23
IE34890B1 (en) 1975-09-17
ES387562A1 (en) 1974-01-01
CS163747B2 (en) 1975-11-07
GB1317425A (en) 1973-05-16
CS163748B2 (en) 1975-11-07
SU379091A3 (en) 1973-04-18

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