CA913077A - Process of preparing n-substituted 14-hydroxydihydronormorphines - Google Patents
Process of preparing n-substituted 14-hydroxydihydronormorphinesInfo
- Publication number
- CA913077A CA913077A CA913077A CA913077DA CA913077A CA 913077 A CA913077 A CA 913077A CA 913077 A CA913077 A CA 913077A CA 913077D A CA913077D A CA 913077DA CA 913077 A CA913077 A CA 913077A
- Authority
- CA
- Canada
- Prior art keywords
- hydroxydihydronormorphines
- substituted
- preparing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA913077T |
Publications (1)
Publication Number | Publication Date |
---|---|
CA913077A true CA913077A (en) | 1972-10-24 |
Family
ID=36420635
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA913077A Expired CA913077A (en) | Process of preparing n-substituted 14-hydroxydihydronormorphines |
Country Status (1)
Country | Link |
---|---|
CA (1) | CA913077A (en) |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4161597A (en) * | 1976-12-20 | 1979-07-17 | Research Corporation | N-alkyl-14-hydroxymorphinans and derivatives |
US4232028A (en) * | 1979-06-18 | 1980-11-04 | Sisa, Incorporated | 17-Cyclobutylmethyl-4,5α-epoxy-3-hydroxy-14-methoxy-8α-methylmorphinan-6-one, and method of treating pain with it |
WO1981000409A1 (en) * | 1979-08-09 | 1981-02-19 | Mallinckrodt Inc | Intermediate compounds for preparation of morphine derivatives |
US4322426A (en) * | 1980-04-28 | 1982-03-30 | E. I. Du Pont De Nemours And Company | 17-Substituted-6-desoxy-7,8-dihydro-6α-methylnoroxymorphone narcotic antagonists |
US4451470A (en) * | 1982-07-06 | 1984-05-29 | E. I. Du Pont De Nemours And Company | Analgesic, antagonist, and/or anorectic 14-fluoromorphinans |
US4667037A (en) * | 1985-06-06 | 1987-05-19 | E. I. Du Pont De Nemours And Company | Dealkylation of opioid ethers |
US4795813A (en) * | 1981-08-17 | 1989-01-03 | The Florida Board Of Regents On Behalf Of The Florida State University | Synthesis of derivatives of codeine and other 3-O-alkylmorphines |
WO1991005768A1 (en) * | 1989-10-16 | 1991-05-02 | The United States Of America, Represented By The Secretary, United States Department Of Commerce | Total synthesis of northebaine, normorphine, noroxymorphone enantiomers and derivatives via n-nor intermediates |
US5668285A (en) * | 1986-10-31 | 1997-09-16 | The United States Of America As Represented By The Department Of Health And Human Services | Total synthesis of northebaine, normophine, noroxymorphone enantiomers and derivatives via N-Nor intermediates |
WO2012151669A1 (en) * | 2011-05-06 | 2012-11-15 | Brock University | Process for the preparation of morphine analogs via metal catalyzed n-demethylation/functionalization and intramolecular group transfer |
-
0
- CA CA913077A patent/CA913077A/en not_active Expired
Cited By (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4161597A (en) * | 1976-12-20 | 1979-07-17 | Research Corporation | N-alkyl-14-hydroxymorphinans and derivatives |
US4232028A (en) * | 1979-06-18 | 1980-11-04 | Sisa, Incorporated | 17-Cyclobutylmethyl-4,5α-epoxy-3-hydroxy-14-methoxy-8α-methylmorphinan-6-one, and method of treating pain with it |
WO1981000409A1 (en) * | 1979-08-09 | 1981-02-19 | Mallinckrodt Inc | Intermediate compounds for preparation of morphine derivatives |
US4322426A (en) * | 1980-04-28 | 1982-03-30 | E. I. Du Pont De Nemours And Company | 17-Substituted-6-desoxy-7,8-dihydro-6α-methylnoroxymorphone narcotic antagonists |
US4795813A (en) * | 1981-08-17 | 1989-01-03 | The Florida Board Of Regents On Behalf Of The Florida State University | Synthesis of derivatives of codeine and other 3-O-alkylmorphines |
US4451470A (en) * | 1982-07-06 | 1984-05-29 | E. I. Du Pont De Nemours And Company | Analgesic, antagonist, and/or anorectic 14-fluoromorphinans |
US4667037A (en) * | 1985-06-06 | 1987-05-19 | E. I. Du Pont De Nemours And Company | Dealkylation of opioid ethers |
US5668285A (en) * | 1986-10-31 | 1997-09-16 | The United States Of America As Represented By The Department Of Health And Human Services | Total synthesis of northebaine, normophine, noroxymorphone enantiomers and derivatives via N-Nor intermediates |
WO1991005768A1 (en) * | 1989-10-16 | 1991-05-02 | The United States Of America, Represented By The Secretary, United States Department Of Commerce | Total synthesis of northebaine, normorphine, noroxymorphone enantiomers and derivatives via n-nor intermediates |
WO2012151669A1 (en) * | 2011-05-06 | 2012-11-15 | Brock University | Process for the preparation of morphine analogs via metal catalyzed n-demethylation/functionalization and intramolecular group transfer |
CN103619847A (en) * | 2011-05-06 | 2014-03-05 | 布鲁克大学 | Process for the preparation of morphine analogs via metal catalyzed N-demethylation/functionalization and intramolecular group transfer |
JP2014514339A (en) * | 2011-05-06 | 2014-06-19 | ブロック ユニバーシティ | Process for the preparation of morphine analogues by metal-catalyzed N-demethylation / functionalization and intramolecular group transfer |
US8946214B2 (en) | 2011-05-06 | 2015-02-03 | Brock University | Process for the preparation of morphine analogs via metal catalyzed N-demethylation/functionalization and intramolecular group transfer |
US9108967B2 (en) | 2011-05-06 | 2015-08-18 | Brock University | Process for the preparation of morphine analogs via metal catalyzed N-demethylation/functionalization and intramolecular group transfer |
US9533993B2 (en) | 2011-05-06 | 2017-01-03 | Brock University | Process for the preparation of morphine analogs via metal catalyzed N-demethylation/functionalization and intramolecular group transfer |
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