CA3233741A1 - Marqueurs microsatellites - Google Patents

Marqueurs microsatellites Download PDF

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Publication number
CA3233741A1
CA3233741A1 CA3233741A CA3233741A CA3233741A1 CA 3233741 A1 CA3233741 A1 CA 3233741A1 CA 3233741 A CA3233741 A CA 3233741A CA 3233741 A CA3233741 A CA 3233741A CA 3233741 A1 CA3233741 A1 CA 3233741A1
Authority
CA
Canada
Prior art keywords
snp1
markers
microsatellite
msi
marker
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3233741A
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English (en)
Inventor
John Burn
Michael Stewart JACKSON
Francisco Mauro SANTIBANEZ-KOREF
Richard GALLON
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cancer Research Technology Ltd
Original Assignee
Cancer Research Technology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cancer Research Technology Ltd filed Critical Cancer Research Technology Ltd
Publication of CA3233741A1 publication Critical patent/CA3233741A1/fr
Pending legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne de nouveaux procédés pour évaluer des niveaux d'instabilité de microsatellite dans un échantillon et pour évaluer l'importance biologique de variations de séquence identifiées dans un échantillon au cours du séquençage. L'invention concerne en outre l'utilisation de nouveaux marqueurs d'instabilité de microsatellite pour évaluer des niveaux d'instabilité de microsatellite dans un échantillon et pour évaluer l'importance biologique de variations de séquence identifiées dans un échantillon pendant le séquençage. Des kits correspondants sont également décrits.
CA3233741A 2021-10-01 2022-10-03 Marqueurs microsatellites Pending CA3233741A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB2114136.1A GB202114136D0 (en) 2021-10-01 2021-10-01 Microsatellite markers
GB2114136.1 2021-10-01
PCT/GB2022/052500 WO2023052795A1 (fr) 2021-10-01 2022-10-03 Marqueurs microsatellites

Publications (1)

Publication Number Publication Date
CA3233741A1 true CA3233741A1 (fr) 2023-04-06

Family

ID=78497788

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3233741A Pending CA3233741A1 (fr) 2021-10-01 2022-10-03 Marqueurs microsatellites

Country Status (6)

Country Link
KR (1) KR20240095538A (fr)
CN (1) CN118043483A (fr)
AU (1) AU2022357505A1 (fr)
CA (1) CA3233741A1 (fr)
GB (1) GB202114136D0 (fr)
WO (1) WO2023052795A1 (fr)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201614474D0 (en) 2016-08-24 2016-10-05 Univ Of Newcastle Upon Tyne The Methods of identifying microsatellite instability
EP4400601A2 (fr) * 2017-07-12 2024-07-17 Institut Curie Procédé de détection d'une mutation dans une séquence microsatellite
CA3132219A1 (fr) * 2019-03-06 2020-09-10 Inserm (Institut National De La Sante Et De La Recherche Medicale) Procede de diagnostic du syndrome cmmrd
WO2021019197A1 (fr) 2019-07-31 2021-02-04 University Of Newcastle Upon Tyne Procédés d'identification d'instabilité de micro-satellite

Also Published As

Publication number Publication date
GB202114136D0 (en) 2021-11-17
AU2022357505A1 (en) 2024-05-02
CN118043483A (zh) 2024-05-14
KR20240095538A (ko) 2024-06-25
WO2023052795A1 (fr) 2023-04-06

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