CA3163429A1 - Methodes et dispositifs pour un capuchon nerveux forme in situ avec liberation rapide - Google Patents
Methodes et dispositifs pour un capuchon nerveux forme in situ avec liberation rapide Download PDFInfo
- Publication number
- CA3163429A1 CA3163429A1 CA3163429A CA3163429A CA3163429A1 CA 3163429 A1 CA3163429 A1 CA 3163429A1 CA 3163429 A CA3163429 A CA 3163429A CA 3163429 A CA3163429 A CA 3163429A CA 3163429 A1 CA3163429 A1 CA 3163429A1
- Authority
- CA
- Canada
- Prior art keywords
- nerve
- hydrogel
- growth
- cavity
- peg
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/11—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
- A61B17/1128—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis of nerves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00491—Surgical glue applicators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/28—Surgical forceps
- A61B17/285—Surgical forceps combined with cutting implements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/52—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/11—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
- A61B17/1146—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis of tendons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00004—(bio)absorbable, (bio)resorbable, resorptive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00491—Surgical glue applicators
- A61B2017/00495—Surgical glue applicators for two-component glue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/00893—Material properties pharmaceutically effective
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/00898—Material properties expandable upon contact with fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/11—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
- A61B2017/1125—Forceps, specially adapted for performing or assisting anastomosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/11—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
- A61B2017/1132—End-to-end connections
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/32—Materials or treatment for tissue regeneration for nerve reconstruction
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Surgery (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Neurology (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
Abstract
L'invention concerne des méthodes, des dispositifs et des matériaux pour la formation in situ d'un implant pour le traitement d'un nerf. Un site de traitement est positionné à l'intérieur d'une cavité définie par une forme. Un support transformable est introduit dans la cavité pour entourer le site de traitement. Le support subit une transformation et passe d'un état relativement fluide à un état relativement non fluide pour former une barrière protectrice entourant le site de traitement. Le milieu hydrophile coopère avec la surface hydrophobe de la cavité pour faciliter la libération rapide de l'implant de la cavité après la transformation. L'implant peut être un capuchon de nerf inhibant la croissance pour inhiber la formation de névromes suite à une lésion nerveuse planifiée ou traumatique, un conduit permettant la croissance pour faciliter la reconnexion d'un nerf sectionné, ou un ancrage pour stabiliser une électrode de gestion de la douleur par rapport à un nerf. L'accès au site de traitement des nerfs peut être un accès chirurgical ouvert ou par voie percutanée.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202062960564P | 2020-01-13 | 2020-01-13 | |
US62/960,564 | 2020-01-13 | ||
PCT/US2021/013296 WO2021146330A1 (fr) | 2020-01-13 | 2021-01-13 | Méthodes et dispositifs pour un capuchon nerveux formé in situ avec libération rapide |
Publications (1)
Publication Number | Publication Date |
---|---|
CA3163429A1 true CA3163429A1 (fr) | 2021-07-22 |
Family
ID=76864195
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA3163429A Pending CA3163429A1 (fr) | 2020-01-13 | 2021-01-13 | Methodes et dispositifs pour un capuchon nerveux forme in situ avec liberation rapide |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP4090261A4 (fr) |
CN (1) | CN115361912A (fr) |
AU (1) | AU2021207853A1 (fr) |
CA (1) | CA3163429A1 (fr) |
WO (1) | WO2021146330A1 (fr) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11246879B2 (en) | 2016-02-09 | 2022-02-15 | Tulai Therapeutics, Inc. | Methods, agents, and devices for local neuromodulation of autonomic nerves |
AU2017290353B2 (en) | 2016-06-29 | 2023-05-18 | Tulavi Therapeutics, Inc. | Treatment of sepsis and related inflammatory conditions by local neuromodulation of the autonomic nervous system |
CA3105343A1 (fr) | 2018-07-02 | 2020-01-09 | Corinne Bright | Procedes et dispositifs pour un capuchon nerveux forme in situ |
EP4370038A1 (fr) * | 2021-07-14 | 2024-05-22 | Tulavi Therapeutics, Inc. | Procédés et dispositifs de régénération nerveuse |
WO2023183148A1 (fr) * | 2022-03-22 | 2023-09-28 | Vascudyne, Inc. | Enveloppe de nerf effectué à l'aide d'un tissu construit |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE0301974D0 (sv) * | 2003-07-03 | 2003-07-03 | Astra Tech Ab | A device for promoting regeneration of an injured nerve, a kit and a biodegredable sheet for preparing such a device |
JP5702515B2 (ja) * | 2007-12-28 | 2015-04-15 | 東洋紡株式会社 | 神経再生誘導管 |
WO2009094225A2 (fr) * | 2008-01-25 | 2009-07-30 | The Johns Hopkins University | Guides nerveux biodégradables |
CN102264408B (zh) * | 2008-12-31 | 2013-08-14 | 凯希特许有限公司 | 用于向神经组织提供流体流的*** |
CN107427533A (zh) * | 2014-11-15 | 2017-12-01 | 蒂舒金公司 | 用于诱导细胞活动和修饰的装置 |
US20210205501A1 (en) * | 2018-03-15 | 2021-07-08 | Tulavi Therapeutics, Inc. | Systems and methods for gel-based neuromodulation |
CA3105343A1 (fr) * | 2018-07-02 | 2020-01-09 | Corinne Bright | Procedes et dispositifs pour un capuchon nerveux forme in situ |
-
2021
- 2021-01-13 EP EP21741461.4A patent/EP4090261A4/fr active Pending
- 2021-01-13 WO PCT/US2021/013296 patent/WO2021146330A1/fr unknown
- 2021-01-13 CA CA3163429A patent/CA3163429A1/fr active Pending
- 2021-01-13 AU AU2021207853A patent/AU2021207853A1/en active Pending
- 2021-01-13 CN CN202180020944.3A patent/CN115361912A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
CN115361912A (zh) | 2022-11-18 |
EP4090261A1 (fr) | 2022-11-23 |
EP4090261A4 (fr) | 2024-05-15 |
AU2021207853A1 (en) | 2022-08-25 |
WO2021146330A1 (fr) | 2021-07-22 |
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