CA3130439A1 - Methode de traitement de la rosacee chez des patients ages de 65 ans et plus - Google Patents

Methode de traitement de la rosacee chez des patients ages de 65 ans et plus Download PDF

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Publication number
CA3130439A1
CA3130439A1 CA3130439A CA3130439A CA3130439A1 CA 3130439 A1 CA3130439 A1 CA 3130439A1 CA 3130439 A CA3130439 A CA 3130439A CA 3130439 A CA3130439 A CA 3130439A CA 3130439 A1 CA3130439 A1 CA 3130439A1
Authority
CA
Canada
Prior art keywords
regimen
pharmaceutical composition
benzoyl peroxide
treatment
rosacea
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3130439A
Other languages
English (en)
Inventor
Ori NOV
Vered Ram
Ofer Toledano
Ofra Levy-Hacham
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sol Gel Technologies Ltd
Original Assignee
Ram Vered
Sol Gel Technologies Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ram Vered, Sol Gel Technologies Ltd filed Critical Ram Vered
Publication of CA3130439A1 publication Critical patent/CA3130439A1/fr
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/327—Peroxy compounds, e.g. hydroperoxides, peroxides, peroxyacids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/38—Percompounds, e.g. peracids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Birds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne un régime pour le traitement thérapeutique de la rosacée chez des sujets âgés de 65 ans et plus, le régime consistant à appliquer topiquement, sur la peau d'un sujet âgé de 65 ans et plus ayant besoin dudit traitement, une composition pharmaceutique, la composition pharmaceutique comprenant d'environ 1 % en poids/poids à environ 10 % en poids/poids de peroxyde de benzoyle en tant que principe actif, et un véhicule ou excipient pharmaceutiquement acceptable, le peroxyde de benzoyle étant le seul principe actif de ladite composition pharmaceutique, ladite composition pharmaceutique étant appliquée une fois par jour pendant une période d'au moins environ 2 semaines, pour obtenir, dans un groupe de tels sujets, un taux de réussite d'au moins environ 15 %, le taux de réussite étant défini comme le nombre de sujets parvenant à une peau nette ou presque nette sur l'échelle d'évaluation globale de participants (IGA) après traitement avec la composition pharmaceutique.
CA3130439A 2019-02-19 2020-02-19 Methode de traitement de la rosacee chez des patients ages de 65 ans et plus Pending CA3130439A1 (fr)

Applications Claiming Priority (21)

Application Number Priority Date Filing Date Title
US201962807356P 2019-02-19 2019-02-19
US201962807368P 2019-02-19 2019-02-19
US62/807,368 2019-02-19
US62/807,356 2019-02-19
US201962871286P 2019-07-08 2019-07-08
US201962871283P 2019-07-08 2019-07-08
US62/871,283 2019-07-08
US62/871,286 2019-07-08
US201962925258P 2019-10-24 2019-10-24
US62/925,258 2019-10-24
US202062960384P 2020-01-13 2020-01-13
US62/960,384 2020-01-13
US202062972310P 2020-02-10 2020-02-10
US62/972,310 2020-02-10
US202062972896P 2020-02-11 2020-02-11
US62/972,896 2020-02-11
US202062977974P 2020-02-18 2020-02-18
US202062977952P 2020-02-18 2020-02-18
US62/977,974 2020-02-18
US62/977,952 2020-02-18
PCT/IB2020/000121 WO2020170032A2 (fr) 2019-02-19 2020-02-19 Méthode de traitement de la rosacée chez des patients âgés de 65 ans et plus

Publications (1)

Publication Number Publication Date
CA3130439A1 true CA3130439A1 (fr) 2020-08-27

Family

ID=72041117

Family Applications (4)

Application Number Title Priority Date Filing Date
CA3130441A Pending CA3130441A1 (fr) 2019-02-19 2020-02-19 Methode de traitement de symptomes d'erytheme modere a severe chez des patients atteints de rosacee
CA3130362A Pending CA3130362A1 (fr) 2019-02-19 2020-02-19 Procede permettant de fournir un debut d'action precoce dans le traitement de la rosacee
CA3130437A Pending CA3130437A1 (fr) 2019-02-19 2020-02-19 Methode de traitement de la rosacee
CA3130439A Pending CA3130439A1 (fr) 2019-02-19 2020-02-19 Methode de traitement de la rosacee chez des patients ages de 65 ans et plus

Family Applications Before (3)

Application Number Title Priority Date Filing Date
CA3130441A Pending CA3130441A1 (fr) 2019-02-19 2020-02-19 Methode de traitement de symptomes d'erytheme modere a severe chez des patients atteints de rosacee
CA3130362A Pending CA3130362A1 (fr) 2019-02-19 2020-02-19 Procede permettant de fournir un debut d'action precoce dans le traitement de la rosacee
CA3130437A Pending CA3130437A1 (fr) 2019-02-19 2020-02-19 Methode de traitement de la rosacee

Country Status (3)

Country Link
US (15) US10945987B2 (fr)
CA (4) CA3130441A1 (fr)
WO (8) WO2020170030A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10945987B2 (en) * 2019-02-19 2021-03-16 Sol-Gel Technologies Ltd. Method for providing early onset of action in the treatment of rosacea
US20210361583A1 (en) * 2020-05-22 2021-11-25 Sol-Gel Technologies Ltd. Stabilized microcapsules, method of their preparation and uses thereof
WO2023021493A1 (fr) * 2021-08-20 2023-02-23 Sol-Gel Technologies Ltd. Méthode de traitement de la rosacée chez des patients âgés de 35-64 ans

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040171561A1 (en) * 2002-09-03 2004-09-02 Popp Karl F. Topical formulations for treatment of rosacea
US7439241B2 (en) 2003-05-27 2008-10-21 Galderma Laboratories, Inc. Compounds, formulations, and methods for treating or preventing rosacea
FR2886850B1 (fr) 2005-06-10 2007-10-05 Galderma Sa Composition a base d'une avermectine et de peroxyde de benzoyle notamment pour le traitement de la rosacee
US9107844B2 (en) 2006-02-03 2015-08-18 Stiefel Laboratories Inc. Topical skin treating compositions
US10278917B2 (en) 2006-04-14 2019-05-07 Perrigo Israel Pharmaceuticals Ltd. Pharmaceutical compositions comprising silica microspheres
WO2008057411A1 (fr) * 2006-11-02 2008-05-15 Stiefel Laboratories, Inc. Trousses comprenant des tampons de peroxyde de benzoyle et une autre composition de traitement de l'acné, et préparations et méthodes d'utilisation associées
FR2909000B1 (fr) 2006-11-28 2009-02-06 Galderma Res & Dev S N C Snc Compositions comprenant du peroxyde de benzoyle, au moins un derive de l'acide naphtoique et au moins un compose de type polymeres de polyurethane ou des derives de celui-ci, et leurs utilisations.
US20100047357A1 (en) 2007-02-01 2010-02-25 Sol-Gel Technologies Ltd. Compositions for topical application comprising a peroxide and retinoid
KR20090121291A (ko) 2007-02-01 2009-11-25 솔-겔 테크놀로지스 리미티드 산화금속 코팅을 포함한 입자의 제조방법 및 산화금속 코팅을 포함한 입자
WO2009069006A2 (fr) 2007-11-30 2009-06-04 Foamix Ltd. Peroxyde de benzoyle contenant de la mousse
JP5677693B2 (ja) * 2008-06-05 2015-02-25 ドウ ファーマシューティカル サイエンシーズ、インク． 水及び水混和性有機溶媒中に懸濁する低濃度過酸化ベンゾイルを含む局所用医薬品製剤
AU2010203166A1 (en) * 2009-01-05 2010-07-08 Sol-Gel Technologies Ltd. Topical compositions containing coated active agents
US20140121188A1 (en) 2009-10-02 2014-05-01 Foamix Ltd. Compositions for the improved treatment of acne and related disorders
WO2011049547A1 (fr) * 2009-10-21 2011-04-28 Dow Pharmaceutical Sciences, Inc. Procédé pour mouillage d'une poudre contenant du peroxyde de benzoyle
US11071878B2 (en) 2009-12-31 2021-07-27 Sol-Gel Technologies Ltd. Core stabilized microcapsules, method of their preparation and uses thereof
US10653899B2 (en) 2009-12-31 2020-05-19 Sol-Gel Technologies Ltd. Core stabilized microcapsules, method of their preparation and uses thereof
WO2011101868A2 (fr) * 2010-02-18 2011-08-25 Helios Pharmaceuticals Private Limited Préparations pharmaceutiquement stables contenant de la clindamycine et du peroxyde de benzoyle, et méthode associée
US20120064135A1 (en) 2010-09-15 2012-03-15 Norac Pharma Benzoyl Peroxide Composition, Methods for Making Same, and Pharmaceutical or Cosmetic Formulations Comprising Same, and Uses Thereof
DE202011100767U1 (de) * 2011-05-17 2011-12-19 Walter Dubiel Benzoylperoxid 5% Gel als Mittel zur Anwendung gegen Rosazea
ES2786103T3 (es) 2011-06-29 2020-10-08 Sol Gel Tech Ltd Formulaciones tópicas estabilizadas que contienen microcápsulas de núcleo-cubierta
CN108159425A (zh) * 2012-11-27 2018-06-15 索尔-格尔科技有限公司 用于治疗红斑痤疮的组合物
US9687465B2 (en) 2012-11-27 2017-06-27 Sol-Gel Technologies Ltd. Compositions for the treatment of rosacea
US10945987B2 (en) * 2019-02-19 2021-03-16 Sol-Gel Technologies Ltd. Method for providing early onset of action in the treatment of rosacea

Also Published As

Publication number Publication date
US11628155B2 (en) 2023-04-18
CA3130437A1 (fr) 2020-08-27
US11986456B2 (en) 2024-05-21
WO2020170032A3 (fr) 2020-12-03
US20200261402A1 (en) 2020-08-20
US20200261401A1 (en) 2020-08-20
CA3130362A1 (fr) 2020-08-27
US20200261400A1 (en) 2020-08-20
US20210145790A1 (en) 2021-05-20
WO2020170030A3 (fr) 2020-12-03
WO2020170032A2 (fr) 2020-08-27
US20220362204A1 (en) 2022-11-17
WO2020170035A3 (fr) 2020-09-24
WO2020170030A2 (fr) 2020-08-27
US20230364050A1 (en) 2023-11-16
US10933046B2 (en) 2021-03-02
US20230248687A1 (en) 2023-08-10
US11877997B2 (en) 2024-01-23
US20200261395A1 (en) 2020-08-20
WO2020170029A3 (fr) 2020-09-24
WO2020170031A2 (fr) 2020-08-27
WO2020170035A2 (fr) 2020-08-27
US20200261398A1 (en) 2020-08-20
WO2020170031A3 (fr) 2020-10-22
US11426378B2 (en) 2022-08-30
US11541026B2 (en) 2023-01-03
WO2020170033A3 (fr) 2020-09-24
US20220133678A1 (en) 2022-05-05
WO2020170033A2 (fr) 2020-08-27
US20200261399A1 (en) 2020-08-20
WO2020170029A2 (fr) 2020-08-27
CA3130441A1 (fr) 2020-08-27
US20230106220A1 (en) 2023-04-06
US20210169841A1 (en) 2021-06-10
WO2020170033A8 (fr) 2022-06-02
WO2020170034A1 (fr) 2020-08-27
WO2020172333A1 (fr) 2020-08-27
US10945987B2 (en) 2021-03-16
US20200261396A1 (en) 2020-08-20
US20200261397A1 (en) 2020-08-20
US11865100B2 (en) 2024-01-09

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