CA3102263A1 - Methodes et compositions pour le traitement de c. difficile - Google Patents
Methodes et compositions pour le traitement de c. difficile Download PDFInfo
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- CA3102263A1 CA3102263A1 CA3102263A CA3102263A CA3102263A1 CA 3102263 A1 CA3102263 A1 CA 3102263A1 CA 3102263 A CA3102263 A CA 3102263A CA 3102263 A CA3102263 A CA 3102263A CA 3102263 A1 CA3102263 A1 CA 3102263A1
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- bacterial strain
- nciivib
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
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- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
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- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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Abstract
L'invention concerne des compositions et des méthodes pour prévenir, atténuer ou traiter des infections par Clostridium difficile et/ou réduire la gravité d'un ou plusieurs facteurs de risque, signes ou symptômes associés à des infections par C. difficile . En particulier, la technologie de la présente invention concerne des méthodes d'administration d'une quantité efficace d'une composition comprenant des souches de bactéries Bacillus amyloliquefaciens identifiées comme ART24, ART4 et ART 12, à un sujet souffrant d'infections par C. difficile, ou à risque de contracter celles-ci.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862681774P | 2018-06-07 | 2018-06-07 | |
| US62/681,774 | 2018-06-07 | ||
| PCT/US2019/035740 WO2019236806A1 (fr) | 2018-06-07 | 2019-06-06 | Méthodes et compositions pour le traitement de c. difficile |
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| GB201911925D0 (en) | 2019-08-20 | 2019-10-02 | Sporegen Ltd | Formulations for prevention or reduction of c. difficile infections |
| WO2021116983A1 (fr) * | 2019-12-11 | 2021-06-17 | Artugen Therapeutics, Ltd. | Produits comestibles comprenant des souches bactériennes et procédés d'utilisation |
| KR20240006543A (ko) | 2021-04-08 | 2024-01-15 | 에벨로 바이오사이언시즈, 인크. | 박테리아를 함유하는 약학적 조성물 |
| WO2023037247A1 (fr) * | 2021-09-07 | 2023-03-16 | Artugen Therapeutics Ltd. | Compositions comprenant bacillus amyloliquefaciens pour la prévention et le traitement de la rectocolite hémorragique |
| WO2023049268A1 (fr) | 2021-09-24 | 2023-03-30 | Evelo Biosciences, Inc. | Formes pharmaceutiques solides contenant des bactéries et des vésicules extracellulaires microbiennes |
| WO2023114293A1 (fr) | 2021-12-14 | 2023-06-22 | Evelo Biosciences, Inc. | Dosages de vésicules extracellulaires |
| WO2024047527A1 (fr) * | 2022-09-01 | 2024-03-07 | Artugen Therapeutics Ltd. | Méthodes et compositions pour prévenir et traiter une neuropathie périphérique causée par la chimiothérapie |
| WO2024102226A1 (fr) | 2022-10-14 | 2024-05-16 | Evelo Biosciences, Inc. | Procédés de dosage de substances médicamenteuses et de produits médicamenteux à l'aide de lignées cellulaires comportant des gènes rapporteurs inductibles par nf-kb |
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| EP1796070A1 (fr) | 2005-12-08 | 2007-06-13 | Thomson Licensing | Affichage lumineux et procédé de commande correspondant |
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| EP3486313A1 (fr) | 2012-04-13 | 2019-05-22 | Chr. Hansen A/S | Souches de bacillus sensibles aux antibiotiques ayant un effet antimicrobien contre e. coli et clostridium perfringens et ayant une forte capacité de sporulation |
| RU2509148C1 (ru) * | 2012-08-31 | 2014-03-10 | Общество с ограниченной ответственностью "НОВА" | ШТАММ Bacillus amyloliquefaciens ВКМ В-2714D, ОБЛАДАЮЩИЙ ВЫРАЖЕННЫМ АНТАГОНИЗМОМ ПО ОТНОШЕНИЮ К Salmonella typhi, Staphylococcus aureus, Listeria monocytogenes И РЕЗИСТЕНТНОСТЬЮ К ТЕТРАЦИКЛИНУ И ТРИМЕТОПРИМУ |
| CN110917220A (zh) * | 2013-02-04 | 2020-03-27 | 赛里斯治疗公司 | 治疗组合物及其使用方法 |
| US10716310B2 (en) | 2014-03-13 | 2020-07-21 | Phibro Animal Health Corporation | Strains of bacillus for inhibiting foodborne pathogens |
| CA2956179C (fr) | 2014-07-25 | 2023-12-12 | The University Of Queensland | Compositions probiotiques de bacillus amyloliquefaciens, procedes de production, et methodes d'utilisation |
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| JP6595761B2 (ja) * | 2014-12-19 | 2019-10-23 | 東亜薬品工業株式会社 | バチルスアミロリキファシエンス菌株及び該菌株を含む抗菌組成物 |
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| CN104974950B (zh) | 2015-05-11 | 2018-10-12 | 山东大学（威海） | 一种海洋解淀粉芽孢杆菌及其用途 |
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| KR20160141267A (ko) | 2015-05-29 | 2016-12-08 | 대한민국(농촌진흥청장) | 항균 활성을 나타내는 바실러스 아밀로리퀴페시언스(Bacillus amyloliquefacience) 균주 및 이의 용도 |
| WO2019175782A1 (fr) * | 2018-03-12 | 2019-09-19 | Better Air International Limited | Compositions comportant des souches bactériennes et utilisation de celles-ci dans la surveillance de micro-organismes pathogènes |
| WO2019236806A1 (fr) * | 2018-06-07 | 2019-12-12 | Artugen Therapeutics Ltd. | Méthodes et compositions pour le traitement de c. difficile |
| WO2021116983A1 (fr) * | 2019-12-11 | 2021-06-17 | Artugen Therapeutics, Ltd. | Produits comestibles comprenant des souches bactériennes et procédés d'utilisation |
| KR20240006543A (ko) * | 2021-04-08 | 2024-01-15 | 에벨로 바이오사이언시즈, 인크. | 박테리아를 함유하는 약학적 조성물 |
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