CA3045110A1 - Derives de tyrosine et compositions les comprenant - Google Patents
Derives de tyrosine et compositions les comprenant Download PDFInfo
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- CA3045110A1 CA3045110A1 CA3045110A CA3045110A CA3045110A1 CA 3045110 A1 CA3045110 A1 CA 3045110A1 CA 3045110 A CA3045110 A CA 3045110A CA 3045110 A CA3045110 A CA 3045110A CA 3045110 A1 CA3045110 A1 CA 3045110A1
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- CA
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- Prior art keywords
- cancer
- tyrosine
- methyl
- composition
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
L'invention concerne des compositions et des kits comprenant un inhibiteur de la tyrosine hydroxylase et un agent anticancéreux qui est chimiquement lié à, ou physiquement associé à, l'inhibiteur de la tyrosine hydroxylase. L'invention concerne également des procédés de réduction de la prolifération cellulaire chez un sujet comprenant l'administration à un sujet qui en a besoin d'une composition comprenant un inhibiteur de la tyrosine hydroxylase et un agent anticancéreux qui est lié chimiquement à, ou physiquement associé à, l'inhibiteur de la tyrosine hydroxylase.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15/365,120 | 2016-11-30 | ||
| US15/365,120 US20170080093A1 (en) | 2013-10-22 | 2016-11-30 | Tyrosine Derivatives And Compositions Comprising Them |
| PCT/US2017/063865 WO2018102506A1 (fr) | 2016-11-30 | 2017-11-30 | Dérivés de tyrosine et compositions les comprenant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3045110A1 true CA3045110A1 (fr) | 2018-06-07 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3045110A Pending CA3045110A1 (fr) | 2016-11-30 | 2017-11-30 | Derives de tyrosine et compositions les comprenant |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP3548086A1 (fr) |
| JP (2) | JP2019536783A (fr) |
| KR (1) | KR20190089191A (fr) |
| CN (1) | CN110062633A (fr) |
| AU (1) | AU2017368135A1 (fr) |
| BR (1) | BR112019011033A2 (fr) |
| CA (1) | CA3045110A1 (fr) |
| EA (1) | EA201991305A1 (fr) |
| IL (1) | IL266840A (fr) |
| MX (1) | MX2019006326A (fr) |
| PH (1) | PH12019501186A1 (fr) |
| WO (1) | WO2018102506A1 (fr) |
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| CN111743887A (zh) * | 2019-03-26 | 2020-10-09 | 深圳先进技术研究院 | α-甲基酪氨酸或其衍生物的用途 |
| MX2021013901A (es) | 2019-05-14 | 2022-04-12 | Tyme Inc | Composiciones y métodos para el tratamiento del cáncer. |
| CA3167918A1 (fr) * | 2020-01-17 | 2021-07-22 | Tyme, Inc. | Compositions et methodes de modulation du cancer |
| US10905698B1 (en) | 2020-05-14 | 2021-02-02 | Tyme, Inc. | Methods of treating SARS-COV-2 infections |
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| TWI323662B (en) * | 2002-11-15 | 2010-04-21 | Telik Inc | Combination cancer therapy with a gst-activated anticancer compound and another anticancer therapy |
| EP3075247B1 (fr) * | 2004-02-02 | 2022-10-12 | BioSight Ltd. | Remedes conjugues de therapie et diagnostic du cancer |
| CN101516899B (zh) * | 2006-04-19 | 2016-07-06 | 得克萨斯大学体系董事会 | 细胞成像和治疗的组合物和方法 |
| PL2200431T3 (pl) * | 2007-09-10 | 2017-01-31 | Boston Biomedical Inc | Nowe kompozycje i metody służące leczeniu raka |
| PL2804599T3 (pl) * | 2012-01-17 | 2019-06-28 | Tyme, Inc. | Terapia skojarzona do leczenia nowotworu złośliwego |
| US9585841B2 (en) * | 2013-10-22 | 2017-03-07 | Tyme, Inc. | Tyrosine derivatives and compositions comprising them |
-
2017
- 2017-11-30 EP EP17817552.7A patent/EP3548086A1/fr active Pending
- 2017-11-30 AU AU2017368135A patent/AU2017368135A1/en not_active Abandoned
- 2017-11-30 KR KR1020197018473A patent/KR20190089191A/ko not_active IP Right Cessation
- 2017-11-30 BR BR112019011033A patent/BR112019011033A2/pt unknown
- 2017-11-30 WO PCT/US2017/063865 patent/WO2018102506A1/fr unknown
- 2017-11-30 MX MX2019006326A patent/MX2019006326A/es unknown
- 2017-11-30 EA EA201991305A patent/EA201991305A1/ru unknown
- 2017-11-30 CN CN201780074235.7A patent/CN110062633A/zh active Pending
- 2017-11-30 CA CA3045110A patent/CA3045110A1/fr active Pending
- 2017-11-30 JP JP2019528632A patent/JP2019536783A/ja active Pending
-
2019
- 2019-05-23 IL IL266840A patent/IL266840A/en unknown
- 2019-05-29 PH PH12019501186A patent/PH12019501186A1/en unknown
-
2022
- 2022-08-01 JP JP2022122538A patent/JP2022153587A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| MX2019006326A (es) | 2019-07-12 |
| KR20190089191A (ko) | 2019-07-30 |
| CN110062633A (zh) | 2019-07-26 |
| EP3548086A1 (fr) | 2019-10-09 |
| WO2018102506A1 (fr) | 2018-06-07 |
| JP2019536783A (ja) | 2019-12-19 |
| BR112019011033A2 (pt) | 2019-10-15 |
| JP2022153587A (ja) | 2022-10-12 |
| EA201991305A1 (ru) | 2019-10-31 |
| IL266840A (en) | 2019-07-31 |
| PH12019501186A1 (en) | 2020-02-10 |
| AU2017368135A1 (en) | 2019-06-13 |
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