CA2993423C - Anticorps de liaison a l'il-8 et leurs utilisations - Google Patents
Anticorps de liaison a l'il-8 et leurs utilisations Download PDFInfo
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- CA2993423C CA2993423C CA2993423A CA2993423A CA2993423C CA 2993423 C CA2993423 C CA 2993423C CA 2993423 A CA2993423 A CA 2993423A CA 2993423 A CA2993423 A CA 2993423A CA 2993423 C CA2993423 C CA 2993423C
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Classifications
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
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- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/565—Complementarity determining region [CDR]
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Abstract
Un aspect non exclusif de l'invention concerne de nouveaux anticorps anti-IL-8 qui sont supérieurs à titre de produits pharmaceutiques.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2015185254 | 2015-09-18 | ||
JP2015-185254 | 2015-09-18 | ||
PCT/JP2016/003616 WO2017046994A1 (fr) | 2015-09-18 | 2016-08-05 | Anticorps de liaison à l'il-8 et leurs utilisations |
Publications (2)
Publication Number | Publication Date |
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CA2993423A1 CA2993423A1 (fr) | 2017-03-23 |
CA2993423C true CA2993423C (fr) | 2024-03-12 |
Family
ID=56738152
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CA2993423A Active CA2993423C (fr) | 2015-09-18 | 2016-08-05 | Anticorps de liaison a l'il-8 et leurs utilisations |
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EP (1) | EP3350202A1 (fr) |
JP (4) | JP6266164B2 (fr) |
KR (3) | KR101920175B1 (fr) |
CN (2) | CN113372443A (fr) |
AR (1) | AR105634A1 (fr) |
AU (1) | AU2016323088B2 (fr) |
BR (1) | BR112018002432A2 (fr) |
CA (1) | CA2993423C (fr) |
CL (1) | CL2018000699A1 (fr) |
CO (1) | CO2018004056A2 (fr) |
CR (1) | CR20180217A (fr) |
HK (1) | HK1252615A1 (fr) |
IL (2) | IL258088B2 (fr) |
MA (1) | MA42808A (fr) |
MX (2) | MX2018003005A (fr) |
PE (1) | PE20181336A1 (fr) |
PH (1) | PH12018500386A1 (fr) |
RU (1) | RU2728430C2 (fr) |
TW (4) | TW202342532A (fr) |
UA (1) | UA120981C2 (fr) |
WO (1) | WO2017046994A1 (fr) |
ZA (1) | ZA201800536B (fr) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2006381B1 (fr) | 2006-03-31 | 2016-02-03 | Chugai Seiyaku Kabushiki Kaisha | Procédé de régulation de la pharmacocinétique sanguine des anticorps |
PL2202245T3 (pl) | 2007-09-26 | 2017-02-28 | Chugai Seiyaku Kabushiki Kaisha | Sposób modyfikowania punktu izoelektrycznego przeciwciała poprzez podstawienie aminokwasu w cdr |
ES2563483T3 (es) | 2008-04-11 | 2016-03-15 | Chugai Seiyaku Kabushiki Kaisha | Molécula de unión a antígeno capaz de unirse repetidamente a dos o más moléculas de antígeno |
US20140234340A1 (en) | 2010-11-30 | 2014-08-21 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly |
CN107964042B (zh) | 2012-05-30 | 2022-04-19 | 中外制药株式会社 | 靶组织特异性抗原结合分子 |
WO2014030750A1 (fr) | 2012-08-24 | 2014-02-27 | 中外製薬株式会社 | ANTICORPS Fc SPÉCIFIQUE À FcyRII DE SOURIS |
CA2882272C (fr) | 2012-08-24 | 2023-08-29 | Chugai Seiyaku Kabushiki Kaisha | Variant de la region fc specifique a fc.gamma.riib |
EP2982689B1 (fr) | 2013-04-02 | 2020-08-26 | Chugai Seiyaku Kabushiki Kaisha | Variant de région fc |
KR102284503B1 (ko) | 2013-12-04 | 2021-07-30 | 추가이 세이야쿠 가부시키가이샤 | 화합물의 농도에 따라 항원 결합능이 변화되는 항원 결합 분자 및 그의 라이브러리 |
SG11201700841QA (en) | 2014-12-19 | 2017-03-30 | Chugai Pharmaceutical Co Ltd | Anti-myostatin antibodies, polypeptides containing variant fc regions, and methods of use |
CN107108729A (zh) | 2015-02-05 | 2017-08-29 | 中外制药株式会社 | 包含离子浓度依赖性的抗原结合结构域的抗体,fc区变体,il‑8‑结合抗体,及其应用 |
TW202342532A (zh) * | 2015-09-18 | 2023-11-01 | 日商中外製藥股份有限公司 | Il-8結合抗體及其用途 |
JP7141336B2 (ja) | 2015-12-25 | 2022-09-22 | 中外製薬株式会社 | 抗ミオスタチン抗体および使用方法 |
CA3026050A1 (fr) * | 2016-08-05 | 2018-02-08 | Chugai Seiyaku Kabushiki Kaisha | Composition pour la prophylaxie ou le traitement de maladies liees a il-8 |
SG10201607778XA (en) | 2016-09-16 | 2018-04-27 | Chugai Pharmaceutical Co Ltd | Anti-Dengue Virus Antibodies, Polypeptides Containing Variant Fc Regions, And Methods Of Use |
EP3634994A4 (fr) * | 2017-06-05 | 2021-06-30 | Janssen Biotech, Inc. | Procédés d'ingénierie de charge de surface pour la production d'un anticorps bispécifique |
CA3093729A1 (fr) | 2018-03-15 | 2019-09-19 | Chugai Seiyaku Kabushiki Kaisha | Anticorps diriges contre le virus de la dengue presentant une reactivite croisee au virus zika et procedes d'utilisation |
CN112839960A (zh) | 2018-08-10 | 2021-05-25 | 中外制药株式会社 | 抗cd137抗原结合分子及其应用 |
CN113544157A (zh) * | 2019-04-19 | 2021-10-22 | 中外制药株式会社 | 用于检测或捕获样品中的多肽的抗体和组合物,以及用于检测或捕获样品中的多肽的方法 |
KR20220113791A (ko) | 2019-12-18 | 2022-08-16 | 에프. 호프만-라 로슈 아게 | 이중특이적 항-ccl2 항체 |
IL295175A (en) | 2020-01-31 | 2022-09-01 | Chugai Pharmaceutical Co Ltd | A method for preparing a preparation containing a polypeptide with suppressed staining |
TW202144395A (zh) | 2020-02-12 | 2021-12-01 | 日商中外製藥股份有限公司 | 用於癌症之治療的抗cd137抗原結合分子 |
GB2595299B (en) * | 2020-05-21 | 2022-08-03 | Mabsolve Ltd | Modified immunoglobulin FC regions |
MX2023000854A (es) * | 2020-07-28 | 2023-02-15 | Chugai Pharmaceutical Co Ltd | Formulacion de jeringa precargada con aguja con protector de aguja que contiene nuevo anticuerpo modificado. |
WO2022244838A1 (fr) | 2021-05-19 | 2022-11-24 | 中外製薬株式会社 | Procédé de prédiction de la pharmacocinétique in vivo d'une molécule |
KR20240021859A (ko) | 2021-06-18 | 2024-02-19 | 에프. 호프만-라 로슈 아게 | 이중특이적 항-ccl2 항체 |
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US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US4676980A (en) | 1985-09-23 | 1987-06-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Target specific cross-linked heteroantibodies |
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