CA2696486C - Procede pour ameliorer la differenciation des cellules souches mesenchymateuses a l'aide d'un implant tissulaire a double structure - Google Patents

Procede pour ameliorer la differenciation des cellules souches mesenchymateuses a l'aide d'un implant tissulaire a double structure Download PDF

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Publication number
CA2696486C
CA2696486C CA2696486A CA2696486A CA2696486C CA 2696486 C CA2696486 C CA 2696486C CA 2696486 A CA2696486 A CA 2696486A CA 2696486 A CA2696486 A CA 2696486A CA 2696486 C CA2696486 C CA 2696486C
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CA
Canada
Prior art keywords
collagen
dsti
implant
cells
stem cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2696486A
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English (en)
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CA2696486A1 (fr
Inventor
Sonya Shortkroff
Joseph Khoury
Laurence J. B. Tarrant
Hans P. I. Claesson
Robert Lane Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ocugen Inc
Original Assignee
Histogenics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/984,124 external-priority patent/US20090124440A1/en
Application filed by Histogenics Corp filed Critical Histogenics Corp
Priority claimed from PCT/US2008/073762 external-priority patent/WO2009026392A1/fr
Publication of CA2696486A1 publication Critical patent/CA2696486A1/fr
Application granted granted Critical
Publication of CA2696486C publication Critical patent/CA2696486C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Vascular Medicine (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Materials For Medical Uses (AREA)

Abstract

La présente invention concerne un implant tissulaire à double structure (DSTI) et un procédé destiné de préparation et d'utilisation de celui-ci permettant son implantation dans des lésions tissulaires. L'implant tissulaire à double structure est destiné à la différenciation, la croissance et la transformation de cellules, de cellules souches, de cellules souches mésenchymateuses et de cellules souches de la moelle osseuse. Le DSTI comprend un support principal et un support secondaire comprenant une solution de collagène soluble combinée à un agent de surface non ionique généré et positionné dans le support principal.
CA2696486A 2007-08-20 2008-08-20 Procede pour ameliorer la differenciation des cellules souches mesenchymateuses a l'aide d'un implant tissulaire a double structure Active CA2696486C (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US11/984,124 2007-08-20
US96788607P 2007-09-06 2007-09-06
US60/967,886 2007-09-06
US11/984,124 US20090124440A1 (en) 2007-11-14 2007-11-14 Gear changing mechanism for chain drive
PCT/US2008/073762 WO2009026392A1 (fr) 2007-08-20 2008-08-20 Procédé pour améliorer la différenciation des cellules souches mésenchymateuses à l'aide d'un implant tissulaire à double structure

Publications (2)

Publication Number Publication Date
CA2696486A1 CA2696486A1 (fr) 2009-02-26
CA2696486C true CA2696486C (fr) 2016-03-29

Family

ID=42122764

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2696486A Active CA2696486C (fr) 2007-08-20 2008-08-20 Procede pour ameliorer la differenciation des cellules souches mesenchymateuses a l'aide d'un implant tissulaire a double structure

Country Status (2)

Country Link
AU (1) AU2008288882B2 (fr)
CA (1) CA2696486C (fr)

Also Published As

Publication number Publication date
AU2008288882A1 (en) 2009-02-26
CA2696486A1 (fr) 2009-02-26
AU2008288882B2 (en) 2014-01-09

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Legal Events

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EEER Examination request

Effective date: 20130710