CA2667816A1 - Inhibiteurs de proteases de type cathepsines - Google Patents
Inhibiteurs de proteases de type cathepsines Download PDFInfo
- Publication number
- CA2667816A1 CA2667816A1 CA002667816A CA2667816A CA2667816A1 CA 2667816 A1 CA2667816 A1 CA 2667816A1 CA 002667816 A CA002667816 A CA 002667816A CA 2667816 A CA2667816 A CA 2667816A CA 2667816 A1 CA2667816 A1 CA 2667816A1
- Authority
- CA
- Canada
- Prior art keywords
- compound
- optionally substituted
- cathepsin
- compounds
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/08—Bridged systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Transplantation (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US86250006P | 2006-10-23 | 2006-10-23 | |
US60/862,500 | 2006-10-23 | ||
PCT/US2007/081635 WO2008051763A1 (fr) | 2006-10-23 | 2007-10-17 | Inhibiteurs de protéases de type cathepsines |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2667816A1 true CA2667816A1 (fr) | 2008-05-02 |
Family
ID=39091868
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002667816A Abandoned CA2667816A1 (fr) | 2006-10-23 | 2007-10-17 | Inhibiteurs de proteases de type cathepsines |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP2078027A1 (fr) |
JP (1) | JP2010507681A (fr) |
KR (1) | KR20090064463A (fr) |
CN (1) | CN101589047A (fr) |
AU (1) | AU2007309195A1 (fr) |
BR (1) | BRPI0717348A2 (fr) |
CA (1) | CA2667816A1 (fr) |
MX (1) | MX2009004290A (fr) |
WO (1) | WO2008051763A1 (fr) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2744987C (fr) | 2008-12-02 | 2018-01-16 | Chiralgen, Ltd. | Procede pour la synthese d'acides nucleiques modifies par des atomes de phosphore |
EP2451461A4 (fr) | 2009-07-06 | 2013-05-29 | Ontorii Inc | Nouveaux précurseurs d'acide nucléique et leurs méthodes d'utilisation |
EP2620428B1 (fr) * | 2010-09-24 | 2019-05-22 | Wave Life Sciences Ltd. | Groupe auxiliaire asymétrique |
ES2626488T3 (es) | 2011-07-19 | 2017-07-25 | Wave Life Sciences Pte. Ltd. | Procedimientos para la síntesis de ácidos nucleicos funcionalizados |
US9598458B2 (en) | 2012-07-13 | 2017-03-21 | Wave Life Sciences Japan, Inc. | Asymmetric auxiliary group |
KR102213609B1 (ko) | 2012-07-13 | 2021-02-08 | 웨이브 라이프 사이언시스 리미티드 | 키랄 제어 |
US10149905B2 (en) | 2014-01-15 | 2018-12-11 | Shin Nippon Biomedical Laboratories, Ltd. | Chiral nucleic acid adjuvant having antitumor effect and antitumor agent |
EP3095461A4 (fr) | 2014-01-15 | 2017-08-23 | Shin Nippon Biomedical Laboratories, Ltd. | Adjuvant d'acide nucléique chiral possédant une activité d'induction d'immunité, et activateur d'induction d'immunité |
MY193116A (en) | 2014-01-16 | 2022-09-26 | Wave Life Sciences Ltd | Chiral design |
WO2016014522A1 (fr) | 2014-07-21 | 2016-01-28 | Brandeis University | Inhibiteurs de protéases de désubiquitination |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2812635B1 (fr) * | 2000-08-01 | 2002-10-11 | Aventis Pharma Sa | Nouveaux composes heterocycliques, preparation et utilisation comme medicaments notamment comme anti- bacteriens |
FR2835186B1 (fr) * | 2002-01-28 | 2006-10-20 | Aventis Pharma Sa | Nouveaux composes heterocycliques, actifs comme inhibiteurs de beta-lactamases |
US7297714B2 (en) * | 2003-10-21 | 2007-11-20 | Irm Llc | Inhibitors of cathepsin S |
-
2007
- 2007-10-17 EP EP07844341A patent/EP2078027A1/fr not_active Withdrawn
- 2007-10-17 CN CNA2007800394622A patent/CN101589047A/zh active Pending
- 2007-10-17 BR BRPI0717348-2A2A patent/BRPI0717348A2/pt not_active Application Discontinuation
- 2007-10-17 CA CA002667816A patent/CA2667816A1/fr not_active Abandoned
- 2007-10-17 KR KR1020097008318A patent/KR20090064463A/ko not_active Application Discontinuation
- 2007-10-17 JP JP2009534774A patent/JP2010507681A/ja active Pending
- 2007-10-17 AU AU2007309195A patent/AU2007309195A1/en not_active Abandoned
- 2007-10-17 WO PCT/US2007/081635 patent/WO2008051763A1/fr active Application Filing
- 2007-10-17 MX MX2009004290A patent/MX2009004290A/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2008051763A1 (fr) | 2008-05-02 |
BRPI0717348A2 (pt) | 2013-10-15 |
KR20090064463A (ko) | 2009-06-18 |
JP2010507681A (ja) | 2010-03-11 |
EP2078027A1 (fr) | 2009-07-15 |
AU2007309195A1 (en) | 2008-05-02 |
CN101589047A (zh) | 2009-11-25 |
MX2009004290A (es) | 2009-07-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Dead |