CA2664548A1 - Packaging for 1-(2-methylpropyl)-1h-imidazo[4,5-c]quinolin-4-amine-containing formulation - Google Patents

Packaging for 1-(2-methylpropyl)-1h-imidazo[4,5-c]quinolin-4-amine-containing formulation Download PDF

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Publication number
CA2664548A1
CA2664548A1 CA002664548A CA2664548A CA2664548A1 CA 2664548 A1 CA2664548 A1 CA 2664548A1 CA 002664548 A CA002664548 A CA 002664548A CA 2664548 A CA2664548 A CA 2664548A CA 2664548 A1 CA2664548 A1 CA 2664548A1
Authority
CA
Canada
Prior art keywords
packaged composition
acid
fatty acid
formulation
moisture barrier
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002664548A
Other languages
French (fr)
Other versions
CA2664548C (en
Inventor
Alexis S. Statham
Julie M. Henderson
Kevin G. Lundquist
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medicis Pharmaceutical Corp
Original Assignee
Graceway Pharmaceuticals, Llc
Alexis S. Statham
Julie M. Henderson
Kevin G. Lundquist
3M Innovative Properties Company
Medicis Pharmaceutical Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Graceway Pharmaceuticals, Llc, Alexis S. Statham, Julie M. Henderson, Kevin G. Lundquist, 3M Innovative Properties Company, Medicis Pharmaceutical Corporation filed Critical Graceway Pharmaceuticals, Llc
Publication of CA2664548A1 publication Critical patent/CA2664548A1/en
Application granted granted Critical
Publication of CA2664548C publication Critical patent/CA2664548C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators

Abstract

A packaged composition 1-(2-methylpropyl)-1-H-imidazo[4,5-c]quinolin-4-amine dissolved in a fatty acid formulation and contained in a laminated packaging material having a contact layer that includes an acrylonitrile-methyl acrylate copolymer; an outer layer; and a moisture barrier layer disposed between the contact layer and outer layer.

Claims (23)

1. A packaged composition comprising:
a durable laminated packaging material comprising:
a contact layer comprising an acrylonitrile-methyl acrylate copolymer;
an outer layer; and a moisture barrier layer disposed between the contact layer and outer layer;
and a formulation enclosed within the durable laminated packaging material comprising:
2-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine; and a fatty acid.

2. The packaged composition of claim 1 wherein an adhesive is disposed between the contact layer and the moisture barrier layer.
3. The packaged composition of claim 1 wherein the outer layer and the moisture barrier layer are bonded together by extrusion bonding with a polymer tie layer.
4. The packaged composition of claim 3, wherein the tie layer is polyethylene.
5. The packaged composition of claim 1 wherein the contact layer is 25 microns to 80 microns thick.
6. The packaged composition of claim 1 wherein the moisture barrier layer is 5 microns to 15 microns thick.
7. The packaged composition of claim 1 wherein the outer layer is 5 millimeters to 20 millimeters thick.
8. The packaged composition of claim 1 wherein the moisture barrier layer comprises a metal foil.
9. The packaged composition of claim 1 wherein the moisture barrier layer comprises aluminum.
10. The packaged composition of claim 1 wherein the outer layer comprises an organic polymer.
11. The packaged composition of claim 1 wherein the outer layer comprises polyethylene terephthalate.
12. The packaged composition of claim 1 wherein the fatty acid is selected from the group consisting of isostearic acid, oleic acid, myristic acid, palmitic acid, palmitoleic acid, margaric acid, stearic acid, linoleic acid, linolenic acid, and mixtures thereof.
13. The packaged composition of claim 12 wherein the fatty acid is isostearic acid, oleic acid, or mixtures thereof.
14. The packaged composition of claim 1 wherein the fatty acid is present in an amount of at least 15% by weight based on the total weight of the formulation.
15. The packaged composition of claim 1 wherein the fatty acid is present in an amount of at least 20% by weight based on the total weight of the formulation.
16. The packaged composition of claim 1 wherein the fatty acid is present in an amount of about 25% by weight based on the total weight of the formulation.
17. The packaged composition of claim 14 wherein the fatty acid is selected from the group consisting of isostearic acid, oleic acid, or mixtures thereof.
18. The packaged composition of claim 17, wherein 1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine is present in an amount of 5% by weight of the formulation.
19. The packaged composition of claim 18, wherein the fatty acid is isostearic acid.
20. The packaged composition of claim 18, wherein the fatty acid is oleic acid.
21. The packaged composition of claim 1 wherein the 1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine-containing formulation further comprises a preservative.
22. The packaged composition of claim 21 wherein the preservative is selected from the group consisting of methylparaben, propylparaben, benzyl alcohol, and mixtures thereof.
23. The packaged composition of claim 1 wherein the 1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine formulation further comprises an emollient, an emulsifier, a thickener, a solubilizing agent, or mixtures thereof.
CA2664548A 2006-12-29 2006-12-29 Packaging for 1-(2-methylpropyl)-1h-imidazo[4,5-c]quinolin-4-amine-containing formulation Expired - Fee Related CA2664548C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2006/049518 WO2008082382A1 (en) 2006-12-29 2006-12-29 Packaging for 1-(2-methylpropyl)-1h-imidazo[4,5-c]quinolin-4-amine containing formulation

Publications (2)

Publication Number Publication Date
CA2664548A1 true CA2664548A1 (en) 2008-07-10
CA2664548C CA2664548C (en) 2014-04-08

Family

ID=39588894

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2664548A Expired - Fee Related CA2664548C (en) 2006-12-29 2006-12-29 Packaging for 1-(2-methylpropyl)-1h-imidazo[4,5-c]quinolin-4-amine-containing formulation

Country Status (2)

Country Link
CA (1) CA2664548C (en)
WO (1) WO2008082382A1 (en)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4686125A (en) * 1984-09-28 1987-08-11 Baxter Travenol Laboratories, Inc. Film laminate for sterile flexible containers
US5008110A (en) * 1988-11-10 1991-04-16 The Procter & Gamble Company Storage-stable transdermal patch
CA2134320C (en) * 1993-10-26 2001-01-09 Toshiyuki Hirose Polyolefin multilayer laminate and use thereof
AU2002363954B2 (en) * 2001-11-29 2008-04-03 3M Innovative Properties Company Pharmaceutical formulations comprising an immune response modifier

Also Published As

Publication number Publication date
WO2008082382A1 (en) 2008-07-10
CA2664548C (en) 2014-04-08

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MKLA Lapsed

Effective date: 20161229