CA2648243C - Nanoparticule et formes polymeres d'analogues et d'antagonistes de l'hormone thyroidienne et leurs formulations - Google Patents

Nanoparticule et formes polymeres d'analogues et d'antagonistes de l'hormone thyroidienne et leurs formulations Download PDF

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Publication number
CA2648243C
CA2648243C CA2648243A CA2648243A CA2648243C CA 2648243 C CA2648243 C CA 2648243C CA 2648243 A CA2648243 A CA 2648243A CA 2648243 A CA2648243 A CA 2648243A CA 2648243 C CA2648243 C CA 2648243C
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Prior art keywords
thyroid hormone
tetrac
angiogenesis
analogs
polymer
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Expired - Fee Related
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CA2648243A
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CA2648243A1 (fr
Inventor
Shaker A. Mousa
Faith B. Davis
Paul J. Davis
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NanoPharmaceuticals LLC
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NanoPharmaceuticals LLC
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
    • A61K47/6927—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores
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    • A61P9/00—Drugs for disorders of the cardiovascular system
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Abstract

L'invention concerne des procédés de traitement de sujets souffrant de maladies associées à l'angiogenèse, lesdits procédés comprenant l'administration d'une quantité efficace d'une forme nanoparticule polymère d'un agoniste, d'un agoniste partiel ou d'un antagoniste de l'hormone thyroïdienne afin de favoriser ou d'inhiber l'angiogenèse chez le sujet. L'invention concerne également des formes polymères de l'hormone thyroïdienne ou d'analogues de l'hormone thyroïdienne.
CA2648243A 2006-04-11 2007-04-11 Nanoparticule et formes polymeres d'analogues et d'antagonistes de l'hormone thyroidienne et leurs formulations Expired - Fee Related CA2648243C (fr)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US79123506P 2006-04-11 2006-04-11
US60/791,235 2006-04-11
US83174006P 2006-07-17 2006-07-17
US60/831,740 2006-07-17
US85645006P 2006-11-02 2006-11-02
US60/856,450 2006-11-02
US66304707A 2007-03-15 2007-03-15
US11/663,047 2007-03-15
PCT/US2007/009026 WO2008051291A2 (fr) 2006-04-11 2007-04-11 Nanoparticule et formes polymères d'analogues et d'antagonistes de l'hormone thyroïdienne et leurs formulations

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