CA2621436A1 - Methode de regulation de vitesses de sedimentation - Google Patents

Methode de regulation de vitesses de sedimentation Download PDF

Info

Publication number: CA2621436A1
Authority: CA; Canada
Prior art keywords: acd; cells; blood; mls; bone marrow
Prior art date: 2007-02-16
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA002621436A

Other languages

English (en)

Inventor

Sherwin Kevy

May Jacobsen

James R. Ellsworth

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Harvest Technologies Corp

Original Assignee

Harvest Technologies Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-02-16

Filing date

2008-02-15

Publication date

2008-08-16

2008-02-15 Application filed by Harvest Technologies Corp filed Critical Harvest Technologies Corp

2008-08-16 Publication of CA2621436A1 publication Critical patent/CA2621436A1/fr

Status Abandoned legal-status Critical Current

Links

238000004062 sedimentation Methods 0.000 title claims abstract description 20
238000000034 method Methods 0.000 title claims description 15
239000012530 fluid Substances 0.000 claims abstract description 30
239000003146 anticoagulant agent Substances 0.000 claims abstract description 15
229940127219 anticoagulant drug Drugs 0.000 claims abstract description 15
210000004369 blood Anatomy 0.000 claims description 23
239000008280 blood Substances 0.000 claims description 23
210000001185 bone marrow Anatomy 0.000 claims description 14
238000012545 processing Methods 0.000 claims description 12
229960002897 heparin Drugs 0.000 claims description 5
229920000669 heparin Polymers 0.000 claims description 5
239000000463 material Substances 0.000 claims description 5
HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims description 4
238000005194 fractionation Methods 0.000 claims description 3
230000010100 anticoagulation Effects 0.000 claims 2
239000000126 substance Substances 0.000 abstract description 10
210000004027 cell Anatomy 0.000 description 25
210000003743 erythrocyte Anatomy 0.000 description 13
239000000306 component Substances 0.000 description 11
238000005119 centrifugation Methods 0.000 description 8
210000004623 platelet-rich plasma Anatomy 0.000 description 7
210000001772 blood platelet Anatomy 0.000 description 5
239000012141 concentrate Substances 0.000 description 3
230000000694 effects Effects 0.000 description 3
239000000203 mixture Substances 0.000 description 3
210000002381 plasma Anatomy 0.000 description 3
238000000926 separation method Methods 0.000 description 3
OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
229910052791 calcium Inorganic materials 0.000 description 2
239000011575 calcium Substances 0.000 description 2
238000005345 coagulation Methods 0.000 description 2
230000015271 coagulation Effects 0.000 description 2
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
230000005484 gravity Effects 0.000 description 2
238000012986 modification Methods 0.000 description 2
230000004048 modification Effects 0.000 description 2
239000013049 sediment Substances 0.000 description 2
239000006228 supernatant Substances 0.000 description 2
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
208000019838 Blood disease Diseases 0.000 description 1
KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 1
206010053567 Coagulopathies Diseases 0.000 description 1
KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 1
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
108010094028 Prothrombin Proteins 0.000 description 1
102100027378 Prothrombin Human genes 0.000 description 1
108090000190 Thrombin Proteins 0.000 description 1
208000007536 Thrombosis Diseases 0.000 description 1
238000010521 absorption reaction Methods 0.000 description 1
239000012503 blood component Substances 0.000 description 1
230000003833 cell viability Effects 0.000 description 1
210000002421 cell wall Anatomy 0.000 description 1
238000006243 chemical reaction Methods 0.000 description 1
230000035602 clotting Effects 0.000 description 1
238000013461 design Methods 0.000 description 1
239000008121 dextrose Substances 0.000 description 1
238000002405 diagnostic procedure Methods 0.000 description 1
238000005534 hematocrit Methods 0.000 description 1
208000014951 hematologic disease Diseases 0.000 description 1
208000018706 hematopoietic system disease Diseases 0.000 description 1
230000002401 inhibitory effect Effects 0.000 description 1
230000003902 lesion Effects 0.000 description 1
210000000265 leukocyte Anatomy 0.000 description 1
238000004519 manufacturing process Methods 0.000 description 1
230000035764 nutrition Effects 0.000 description 1
235000016709 nutrition Nutrition 0.000 description 1
239000002245 particle Substances 0.000 description 1
239000000106 platelet aggregation inhibitor Substances 0.000 description 1
229940039716 prothrombin Drugs 0.000 description 1
238000011084 recovery Methods 0.000 description 1
230000000717 retained effect Effects 0.000 description 1
239000007787 solid Substances 0.000 description 1
210000000130 stem cell Anatomy 0.000 description 1
239000000725 suspension Substances 0.000 description 1
229960004072 thrombin Drugs 0.000 description 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/38—Diluting, dispersing or mixing samples
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood

Landscapes

General Health & Medical Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
Physics & Mathematics (AREA)
General Physics & Mathematics (AREA)
Immunology (AREA)
Pathology (AREA)
External Artificial Organs (AREA)
Investigating Or Analysing Biological Materials (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

CA002621436A 2007-02-16 2008-02-15 Methode de regulation de vitesses de sedimentation Abandoned CA2621436A1 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US90166007P	2007-02-16	2007-02-16
US60/901,660		2007-02-16

Publications (1)

Publication Number	Publication Date
CA2621436A1 true CA2621436A1 (fr)	2008-08-16

Family

ID=39651227

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002621436A Abandoned CA2621436A1 (fr)	2007-02-16	2008-02-15	Methode de regulation de vitesses de sedimentation

Country Status (6)

Country	Link
US (1)	US20080213743A1 (fr)
EP (1)	EP1972380A1 (fr)
JP (1)	JP2008231095A (fr)
CN (1)	CN101513544A (fr)
AU (1)	AU2008200733A1 (fr)
CA (1)	CA2621436A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8984932B2 (en)	2012-07-18	2015-03-24	Theranos, Inc.	Rapid measurement of formed blood component sedimentation rate from small sample volumes
WO2014015177A1 (fr)	2012-07-18	2014-01-23	Theranos, Inc.	Mesure rapide du taux de sédimentation des éléments figurés du sang dans des échantillons de petit volume
CN113588501A (zh) *	2015-12-08	2021-11-02	生物马特里卡公司	降低红细胞沉降速率

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5614106A (en) *	1993-03-12	1997-03-25	Baxter International Inc.	Method and apparatus for collection of platelets
EP1000664B1 (fr) *	1995-04-18	2005-06-15	Gambro, Inc.,	Appareil et procédé de séparation de particules
WO2000061256A1 (fr)	1999-04-12	2000-10-19	Harvest Technologies Corporation	Methode et appareil permettant de produire un plasma riche en plaquettes et/ou un concentre de plaquettes
US8980568B2 (en) *	2001-10-11	2015-03-17	Aviva Biosciences Corporation	Methods and compositions for detecting non-hematopoietic cells from a blood sample
US7291450B2 (en) *	2003-03-28	2007-11-06	Smith & Nephew, Inc.	Preparation of a cell concentrate from a physiological solution

2008
- 2008-02-15 JP JP2008034238A patent/JP2008231095A/ja not_active Abandoned
- 2008-02-15 CA CA002621436A patent/CA2621436A1/fr not_active Abandoned
- 2008-02-15 EP EP08002831A patent/EP1972380A1/fr not_active Withdrawn
- 2008-02-15 AU AU2008200733A patent/AU2008200733A1/en not_active Abandoned
- 2008-02-18 CN CNA2008100807621A patent/CN101513544A/zh active Pending
- 2008-02-19 US US12/071,234 patent/US20080213743A1/en not_active Abandoned

Also Published As

Publication number	Publication date
CN101513544A (zh)	2009-08-26
AU2008200733A1 (en)	2008-09-04
US20080213743A1 (en)	2008-09-04
EP1972380A1 (fr)	2008-09-24
JP2008231095A (ja)	2008-10-02

Legal Events

Date	Code	Title	Description
2008-02-15	EEER	Examination request
2011-03-24	FZDE	Discontinued

Publication	Publication Date	Title
US12011463B2 (en)	2024-06-18	Multilayered blood product
Efeoglu et al.	2004	A modified method for preparing platelet-rich plasma: an experimental study
AU2012202594B2 (en)	2016-04-07	Thrombin isolated from blood and blood fractions
US20080213743A1 (en)	2008-09-04	Method for adjusting sedimentation rates
JP5860736B2 (ja)	2016-02-16	血小板機能を決定するための装置及び方法
Bartels et al.	1996	Intraoperative autotransfusion in aortic surgery: Comparison of whole blood autotransfusion versus cell separation
Reinhart et al.	2014	The passage of a hemodialysis filter affects hemorheology, red cell shape, and platelet aggregation
US20020084221A1 (en)	2002-07-04	Method for precipitating red blood cells
Feuring, A. Gutfleisch, A. Ganschow, E. Richter, H. Eichler, CE Dempfle, HC Tillmann, A. Schultz, M. Wehling	2001	Impact of plasmapheresis on platelet hemostatic capacity in healthy voluntary blood donors detected by the platelet function analyzer PFA-100™
Järemo et al.	1992	Some storage characteristics of buffy coats used for preparation of platelet concentrates
Robert C et al.	1994	In vitro analysis of shed blood from patients undergoing total knee replacement surgery
TWI775179B (zh)	2022-08-21	高濃度血小板血漿分離套組及使用其之方法
Acton	2013	Advances in Blood Research and Application: 2013 Edition
JP2005006821A (ja)	2005-01-13	血液を血漿層／血球層に分離するための採血器具および方法
US20220118441A1 (en)	2022-04-21	Kit for isolation of platelet-rich plasma and the method using the same
Muthu et al.	2022	Standardization and Validation of a High Yield Conventional Platelet-rich Plasma Preparation Protocol
WO2023069027A1 (fr)	2023-04-27	Tube destiné à un procédé avancé d'obtention de fibrine riche en plaquettes
Serrick et al.	2005	Partial bowls using the Haemonetics Cell Saver 5: does it produce a quality product?
Baerlocher et al.	2001	Gel‐filtration of sickle erythrocytes: Separation based on cell deformability
Latza et al.	2000	Platelet function in platelet concentrates during storage: Comparison of two blood cell separators
Persson et al.	1994	A filtrometric study on red blood cells after storage in frozen form
JP2014117347A (ja)	2014-06-30	血清の調製方法及び血清
JPH11192216A (ja)	1999-07-21	血液成分採取用容器