CA2609985A1 - Modulation des dysfonctionnements de la barriere cellulaire - Google Patents
Modulation des dysfonctionnements de la barriere cellulaire Download PDFInfo
- Publication number
- CA2609985A1 CA2609985A1 CA002609985A CA2609985A CA2609985A1 CA 2609985 A1 CA2609985 A1 CA 2609985A1 CA 002609985 A CA002609985 A CA 002609985A CA 2609985 A CA2609985 A CA 2609985A CA 2609985 A1 CA2609985 A1 CA 2609985A1
- Authority
- CA
- Canada
- Prior art keywords
- opioid receptor
- opioid
- aeruginosa
- receptor antagonist
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68756805P | 2005-06-03 | 2005-06-03 | |
US60/687,568 | 2005-06-03 | ||
US73100905P | 2005-10-28 | 2005-10-28 | |
US60/731,009 | 2005-10-28 | ||
US76085106P | 2006-01-20 | 2006-01-20 | |
US60/760,851 | 2006-01-20 | ||
USPCT/US2006/07892 | 2006-03-07 | ||
PCT/US2006/007892 WO2006096626A2 (fr) | 2005-03-07 | 2006-03-07 | Utilisation d'antagonistes opioides pour l'attenuation de la proliferation et de la migration des cellules endotheliales |
PCT/US2006/021604 WO2007053194A2 (fr) | 2005-06-03 | 2006-06-05 | Modulation des dysfonctionnements de la barriere cellulaire |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2609985A1 true CA2609985A1 (fr) | 2007-05-10 |
Family
ID=38006351
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002609985A Abandoned CA2609985A1 (fr) | 2005-06-03 | 2006-06-05 | Modulation des dysfonctionnements de la barriere cellulaire |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP1901742A2 (fr) |
CA (1) | CA2609985A1 (fr) |
WO (1) | WO2007053194A2 (fr) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT1615646E (pt) | 2003-04-08 | 2015-02-12 | Progenics Pharm Inc | Formulações farmacêuticas com metilnaltrexona |
US9662390B2 (en) | 2005-03-07 | 2017-05-30 | The University Of Chicago | Use of opioid antagonists to attenuate endothelial cell proliferation and migration |
US8518962B2 (en) | 2005-03-07 | 2013-08-27 | The University Of Chicago | Use of opioid antagonists |
US8524731B2 (en) | 2005-03-07 | 2013-09-03 | The University Of Chicago | Use of opioid antagonists to attenuate endothelial cell proliferation and migration |
US9662325B2 (en) | 2005-03-07 | 2017-05-30 | The University Of Chicago | Use of opioid antagonists to attenuate endothelial cell proliferation and migration |
AR057035A1 (es) | 2005-05-25 | 2007-11-14 | Progenics Pharm Inc | SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS |
AR057325A1 (es) | 2005-05-25 | 2007-11-28 | Progenics Pharm Inc | Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos |
JP2009534384A (ja) * | 2006-04-19 | 2009-09-24 | ジル・ピー・スミス | オピオイドアンタゴニストによる炎症性および潰瘍性腸疾患の治療 |
EP2134718A2 (fr) | 2007-03-29 | 2009-12-23 | Progenics Pharmaceuticals, Inc. | Formes cristallines, et leurs utilisations |
EP2137191B8 (fr) | 2007-03-29 | 2016-06-08 | Progenics Pharmaceuticals, Inc. | Antagonistes de récepteurs opioïdes périphériques, et leurs utilisations |
DK2565195T3 (en) | 2007-03-29 | 2015-06-29 | Wyeth Llc | PERIPHERAL OPIOID RECEPTOR AND ANTAGONISTS AND USES THEREOF |
RU2440117C1 (ru) * | 2007-10-05 | 2012-01-20 | Торэй Индастриз, Инк. | Терапевтическое средство для улучшения свойств кожи, включающее в качестве действующего ингредиента производное морфинана или любую из его фармакологически приемлемых кислотно-аддитивных солей |
JP5358587B2 (ja) | 2008-02-06 | 2013-12-04 | プロジェニックス・ファーマシューティカルス・インコーポレイテッド | (r),(r)−2,2’−ビス−メチルナルトレキソンの製造及び用途 |
JP5647098B2 (ja) | 2008-03-21 | 2014-12-24 | ザ ユニヴァーシティー オヴ シカゴ | オピオイド拮抗薬とmTOR阻害薬を用いた治療 |
EP2306829B1 (fr) | 2008-07-01 | 2017-01-04 | University of Chicago | Particules contenant un antagoniste périphérique de récepteur d'opioïde |
CA2676881C (fr) | 2008-09-30 | 2017-04-25 | Wyeth | Antagonistes de recepteurs opioides peripheriques, et leurs utilisations |
ES2951828T3 (es) | 2010-09-23 | 2023-10-25 | Leading Biosciences Inc | Administración de inhibidores de serina proteasa al estómago |
US10485798B2 (en) | 2012-08-22 | 2019-11-26 | Aptapharma Inc. | Methylnaltrexone nasal formulations, methods of making, and use thereof |
CN112641771B (zh) | 2014-03-25 | 2022-04-15 | 恒翼生物医药科技(上海)有限公司 | 用于治疗自身消化的组合物 |
CN117940554A (zh) * | 2022-06-30 | 2024-04-26 | 上海羽冠生物技术有限公司 | 假单胞菌属的活细菌菌株 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4863928A (en) * | 1989-01-04 | 1989-09-05 | Baker Cummins Pharmaceuticals, Inc. | Method of treatment for arthritic and inflammatory diseases |
US20040024006A1 (en) * | 1996-05-06 | 2004-02-05 | Simon David Lew | Opioid pharmaceutical compositions |
US6194382B1 (en) * | 1999-03-03 | 2001-02-27 | Albert Einstein College Of Medicine Of Yeshiva University | Method and composition for treating irritable bowel syndrome using low doses of opioid receptor antagonists |
US6384044B1 (en) * | 1999-11-29 | 2002-05-07 | Bernard Bihari | Method of treating cancer of the prostate |
MX2007015262A (es) * | 2005-06-03 | 2008-02-22 | Univ Chicago | Modulacion de interacciones de celulas huesped de patogenos microbianos. |
-
2006
- 2006-06-05 WO PCT/US2006/021604 patent/WO2007053194A2/fr active Application Filing
- 2006-06-05 EP EP06844131A patent/EP1901742A2/fr not_active Withdrawn
- 2006-06-05 CA CA002609985A patent/CA2609985A1/fr not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1901742A2 (fr) | 2008-03-26 |
WO2007053194A2 (fr) | 2007-05-10 |
WO2007053194A3 (fr) | 2007-08-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Dead |