CA2609378A1 - Methodes et compositions destinees a la regulation du developpement de biofilms - Google Patents

Methodes et compositions destinees a la regulation du developpement de biofilms Download PDF

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Publication number
CA2609378A1
CA2609378A1 CA002609378A CA2609378A CA2609378A1 CA 2609378 A1 CA2609378 A1 CA 2609378A1 CA 002609378 A CA002609378 A CA 002609378A CA 2609378 A CA2609378 A CA 2609378A CA 2609378 A1 CA2609378 A1 CA 2609378A1
Authority
CA
Canada
Prior art keywords
biofilm
nitric oxide
spp
composition
microorganisms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002609378A
Other languages
English (en)
Inventor
Nicolas Barraud
Jeremy S. Webb
Scott A. Rice
Staffan Kjelleberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Environmental Biotechnology CRC Pty Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2005902660A external-priority patent/AU2005902660A0/en
Application filed by Individual filed Critical Individual
Publication of CA2609378A1 publication Critical patent/CA2609378A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/40Peroxides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/16Enzymes or microbial cells immobilised on or in a biological cell
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N41/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom
    • A01N41/12Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom not containing sulfur-to-oxygen bonds, e.g. polysulfides
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/06Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings
    • A01N43/08Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings with oxygen as the ring hetero atom
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/501,3-Diazoles; Hydrogenated 1,3-diazoles
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • A01N59/16Heavy metals; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/375Ascorbic acid, i.e. vitamin C; Salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/26Iron; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06Tripeptides
    • A61K38/063Glutathione
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA002609378A 2005-05-24 2006-05-24 Methodes et compositions destinees a la regulation du developpement de biofilms Abandoned CA2609378A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2005902660 2005-05-24
AU2005902660A AU2005902660A0 (en) 2005-05-24 Methods and compositions for regulating biofilm development
PCT/AU2006/000693 WO2006125262A1 (fr) 2005-05-24 2006-05-24 Methodes et compositions destinees a la regulation du developpement de biofilms

Publications (1)

Publication Number Publication Date
CA2609378A1 true CA2609378A1 (fr) 2006-11-30

Family

ID=37451569

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002609378A Abandoned CA2609378A1 (fr) 2005-05-24 2006-05-24 Methodes et compositions destinees a la regulation du developpement de biofilms

Country Status (9)

Country Link
US (3) US8425945B2 (fr)
EP (2) EP1899451B1 (fr)
JP (1) JP2008542208A (fr)
CN (1) CN101213292A (fr)
CA (1) CA2609378A1 (fr)
DK (2) DK2351828T3 (fr)
IL (2) IL187606A (fr)
TW (1) TW200716741A (fr)
WO (1) WO2006125262A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009124379A1 (fr) * 2008-04-09 2009-10-15 Enox Biopharma, Inc. Cathéters et tubulures inhibant la formation de biofilm
WO2011085484A1 (fr) * 2010-01-13 2011-07-21 Nitric Solutions Inc. Compositions d'oxyde nitrique antimicrobiennes

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ES2731298T3 (es) 2005-05-27 2019-11-14 Univ North Carolina Chapel Hill Partículas de liberación de óxido nítrico para agentes terapéuticos de óxido nítrico y aplicaciones biomédicas
EP2136800A4 (fr) 2007-03-19 2011-10-05 Wisconsin Alumni Res Found Modulation de la détection du quorum bactérien avec des ligands synthétiques
TWI404544B (zh) 2008-08-11 2013-08-11 Colgate Palmolive Co 含珠粒之口腔保健組成物
US11219706B2 (en) 2009-03-11 2022-01-11 Arrow International Llc Enhanced formulations for coating medical devices
US20100233288A1 (en) * 2009-03-11 2010-09-16 Teleflex Medical Incorporated Medical devices containing nitroprusside and antimicrobial agents
DK2467173T3 (da) 2009-08-21 2019-07-29 Novan Inc Sårbandager, fremgangsmåder til anvendelse heraf og fremgangsmåder til dannelse deraf
ES2958410T3 (es) 2009-08-21 2024-02-08 Novan Inc Geles tópicos
US8419899B2 (en) * 2009-09-22 2013-04-16 Sonoco Development Inc. Paperboard containing recycled fibers and method of making the same
KR101275305B1 (ko) * 2010-11-19 2013-06-17 한국생산기술연구원 콜로이달 나노 입자를 이용한 바이오 필름 형성 방지용 기판의 제조방법, 이로부터 제조된 기판 및 상기 기판을 포함하는 수질 검사 센서
GB201020236D0 (en) * 2010-11-30 2011-01-12 Convatec Technologies Inc A composition for detecting biofilms on viable tissues
US8591876B2 (en) 2010-12-15 2013-11-26 Novan, Inc. Methods of decreasing sebum production in the skin
ES2695173T3 (es) 2011-02-28 2019-01-02 Novan Inc Partículas de sílice modificadas con S-nitrosotiol que liberan óxido nítrico y procedimientos de fabricación de las mismas
JP2014506923A (ja) * 2011-03-01 2014-03-20 クオラム イノベーションズ リミテッド ライアビリティ カンパニー 病原性バイオフィルムと関連した状態を治療するための物質および方法
US10085447B2 (en) 2011-03-11 2018-10-02 Ecolab Usa Inc. Acidic biofilm remediation
DK2710016T3 (en) * 2011-05-16 2016-08-15 Newsouth Innovations Pty Ltd REGULATION OF NITROGEN OXIDE RELEASE AND BIOFILM DEVELOPMENT
CA3075772C (fr) 2011-05-31 2022-07-19 Hutchison Biofilm Medical Solutions Limited Dispersion et detachement d'agregats cellulaires
US20150011454A1 (en) * 2011-12-27 2015-01-08 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Stable aqueous nitric oxide solutions, methods of their preparation and uses thereof
WO2013103780A1 (fr) * 2012-01-06 2013-07-11 Trustees Of Boston University Compositions et procédés pour amplifier la production endogène d'espèces réactives de l'oxygène (ros) à partir de bactéries
JPWO2014017233A1 (ja) * 2012-07-27 2016-07-07 住友重機械工業株式会社 微生物用活性調節剤及び微生物の活性を調節する方法
WO2014016979A1 (fr) * 2012-07-27 2014-01-30 住友重機械工業株式会社 Modulateur d'activité microbienne et procédé de modulation d'activité microbienne
JP2015155534A (ja) * 2014-01-17 2015-08-27 住友重機械工業株式会社 バイオフィルム分解剤及びバイオフィルムの分解方法
WO2015130602A2 (fr) 2014-02-28 2015-09-03 Michigan Molecular Institute Composition à libération prolongée utilisant des polyesters hyperramifiés biodégradables d'origine biologique
AU2015243508B2 (en) * 2014-04-09 2019-05-02 Nch Corporation System and method for detecting biofilm growth in water systems
AU2015337804A1 (en) * 2014-10-31 2017-05-25 Ixom Operations Pty Ltd Method and compositions for preventing bacterial corrosion of a substrate
WO2016094591A1 (fr) 2014-12-09 2016-06-16 Miox Corporation Procédés permettant la production électrolytique directe de solutions d'halosulfamate ou d'halosulfonamide aqueuses stables à concentration élevée
CN105084552A (zh) * 2015-07-31 2015-11-25 北京师范大学 利用n-酰基高丝氨酸内酯类强化好氧氨氧化菌聚集的方法
CN105062478B (zh) * 2015-08-10 2017-08-22 中国科学院新疆理化技术研究所 一种制备铁氧体‑铁酸铋复合荧光材料的生物方法
JP2018532710A (ja) * 2015-09-09 2018-11-08 アドバンスド インハラーション セラピーズ(エーアイティー) リミテッド 細気管支炎を有する乳幼児のための一酸化窒素吸入療法
US10172362B2 (en) * 2015-10-26 2019-01-08 The Penn State Research Foundation Biofilms, components and methods of use to reduce biofouling and contamination
EP3318266A1 (fr) * 2016-11-03 2018-05-09 Joachim Riethmüller Composition pharmaceutique destinée à être utilisée dans le traitement d'une maladie respiratoire
AU2017362500A1 (en) * 2016-11-17 2019-06-13 Renovion, Inc. Treatment of Respiratory Tract Diseases and Infections with Ascorbic Acid Compositions
WO2019046958A1 (fr) * 2017-09-08 2019-03-14 Uti Limited Partnership Nitroprussiate de sodium et nitrate pour l'inhibition métabolique de microbes réducteurs de sulfate pour contrôler la production de sulfure
US10526278B2 (en) 2017-10-19 2020-01-07 Wisconsin Alumni Research Foundation Inhibitors of quorum sensing receptor LasR
KR20200089702A (ko) 2017-11-17 2020-07-27 레노비온, 아이엔씨. 안정한 아스코르빈산 조성물 및 그의 사용 방법
WO2019157295A1 (fr) * 2018-02-09 2019-08-15 The Trustees Of Columbia University In The City Of New York Traitement d'infections à l'aide d'un inhibiteur d'oxydases de type cbb3
US10927397B2 (en) 2018-10-16 2021-02-23 Sterilex, Llc Compositions, devices and methods for detecting biofilms
JP2023513750A (ja) * 2020-02-14 2023-04-03 ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル 耐性呼吸細菌における感受性の改善及び抗生物質耐性の低下のための外因性一酸化窒素
US20230270900A1 (en) * 2020-06-04 2023-08-31 Berkshire Holding Corporation Cleaning kit having a solute
US20230321043A1 (en) 2020-08-27 2023-10-12 Københavns Universitet Compounds having pseudomonas anti-biofilm properties

Family Cites Families (10)

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US5906987A (en) * 1997-03-10 1999-05-25 Schering Aktiengesellschaft And Board Of Regents Treatment of male climacteric disorders with nitric oxide synthase substrates and/or donors, in combination with androgens and/or aromatase inhibitors
US6610282B1 (en) 1998-05-05 2003-08-26 Rohm And Haas Company Polymeric controlled release compositions
US20040151785A1 (en) * 1998-10-06 2004-08-05 Diamedica Inc. Method for treating insulin resistance through hepatic nitric oxide
US20040220265A1 (en) * 2002-07-25 2004-11-04 Celluar Sciences, Inc. Method for treating pulmonary disease states in mammals by altering indigenous in vivo levels of nitric oxide
JP4047116B2 (ja) * 2002-09-19 2008-02-13 キヤノン株式会社 画像形成システム
US7485324B2 (en) * 2003-09-29 2009-02-03 Pulmonox Technologies Corporation Use of exogenous gaseous nitric oxide in the treatment and disinfection of biofilms
CA2549544A1 (fr) 2003-12-15 2005-06-23 Nitricare Hb Dispositif et procede d'administration d'agents therapeutiques
US7829553B2 (en) * 2004-02-09 2010-11-09 Amulet Pharmaceuticals, Inc. Nitric oxide-releasing polymers
WO2005117545A2 (fr) 2004-05-27 2005-12-15 Children's Hospital Medical Center Inhibiteurs de la dioxygenase de monoxyde d'azote
US20070154570A1 (en) * 2004-09-29 2007-07-05 Miller Christopher C Use of nitric oxide in the treatment and disinfection of biofilms

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009124379A1 (fr) * 2008-04-09 2009-10-15 Enox Biopharma, Inc. Cathéters et tubulures inhibant la formation de biofilm
WO2011085484A1 (fr) * 2010-01-13 2011-07-21 Nitric Solutions Inc. Compositions d'oxyde nitrique antimicrobiennes

Also Published As

Publication number Publication date
IL187606A0 (en) 2008-03-20
IL187606A (en) 2012-07-31
IL210816A0 (en) 2011-04-28
EP1899451A4 (fr) 2008-11-26
TW200716741A (en) 2007-05-01
EP1899451A1 (fr) 2008-03-19
US20160089396A1 (en) 2016-03-31
US20130230606A1 (en) 2013-09-05
DK1899451T3 (en) 2017-01-23
JP2008542208A (ja) 2008-11-27
CN101213292A (zh) 2008-07-02
US8425945B2 (en) 2013-04-23
DK2351828T3 (en) 2018-01-22
US20090214674A1 (en) 2009-08-27
EP1899451B1 (fr) 2016-10-12
EP2351828A1 (fr) 2011-08-03
WO2006125262A1 (fr) 2006-11-30
EP2351828B1 (fr) 2017-10-18

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