CA2608271C - Facteur viii de croissance epidermique de globule de matiere grasse de lait et sepsis - Google Patents
Facteur viii de croissance epidermique de globule de matiere grasse de lait et sepsis Download PDFInfo
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- CA2608271C CA2608271C CA2608271A CA2608271A CA2608271C CA 2608271 C CA2608271 C CA 2608271C CA 2608271 A CA2608271 A CA 2608271A CA 2608271 A CA2608271 A CA 2608271A CA 2608271 C CA2608271 C CA 2608271C
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- 235000012431 wafers Nutrition 0.000 description 1
- 239000008215 water for injection Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
La présente invention concerne un procédé de traitement d'un mammifère atteint de sepsis ou présentant un risque de sepsis. Cette invention concerne aussi des procédés de prévention ou de traitement d'effet physiologique de sepsis chez un mammifère. Cette invention concerne aussi l'utilisation de facteur VIII (MFG- E8) de facteur croissance épidermique de globule de matière grasse de lait permettant la fabrication d'un médicament destiné à prévention ou au traitement d'un effet physiologique de sepsis chez un mammifère et, l'utilisation de facteur VIII (MFG-E8) de facteur de croissance de matière grasse de lait dans le traitement d'un mammifère atteint de sepsis ou présentant un risque de sepsis.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68062805P | 2005-05-13 | 2005-05-13 | |
US60/680,628 | 2005-05-13 | ||
PCT/US2006/018774 WO2006122327A2 (fr) | 2005-05-13 | 2006-05-12 | Facteur viii de croissance epidermique de globule de matiere grasse de lait et sepsis |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2608271A1 CA2608271A1 (fr) | 2006-11-16 |
CA2608271C true CA2608271C (fr) | 2016-01-19 |
Family
ID=37397353
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2608271A Active CA2608271C (fr) | 2005-05-13 | 2006-05-12 | Facteur viii de croissance epidermique de globule de matiere grasse de lait et sepsis |
Country Status (6)
Country | Link |
---|---|
US (1) | US9321822B2 (fr) |
EP (1) | EP1888096B1 (fr) |
CN (1) | CN101203234B (fr) |
AU (1) | AU2006243905B2 (fr) |
CA (1) | CA2608271C (fr) |
WO (1) | WO2006122327A2 (fr) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2005231395B2 (en) | 2004-03-31 | 2011-06-16 | The Fernstein Institute For Medical Research | Adrenomedullin and adrenomedullin binding protein for ischemia/reperfusion treatment |
US8703693B2 (en) * | 2004-03-31 | 2014-04-22 | The Feinstein Institute For Medical Research | Adrenomedullin and adrenomedullin binding protein for ischemia/reperfusion treatment |
ES2880460T3 (es) * | 2006-03-09 | 2021-11-24 | Aethlon Medical Inc | Eliminación extracorpórea de partículas microvesiculares |
EP2215264B1 (fr) * | 2007-11-15 | 2015-04-01 | The Feinstein Institute for Medical Research | Prévention et traitement d'inflammation et de lésion d'organe après ischémie/reperfusion en utilisant mfg-e8 |
CN101705288B (zh) * | 2009-11-17 | 2011-12-28 | 西北农林科技大学 | 奶山羊mfg-e8基因的单核苷酸多态性及其检测方法 |
CN101705290B (zh) * | 2009-11-17 | 2011-12-28 | 西北农林科技大学 | 奶山羊scd基因的单核苷酸多态性及其检测方法 |
WO2012149254A2 (fr) * | 2011-04-28 | 2012-11-01 | The Feinstein Institute For Medical Research | Mfg-e8 et ses utilisations |
DK2808028T3 (da) * | 2011-11-21 | 2019-10-07 | Univ Tsukuba | Aktivitetsmodulator, medicinsk middel omfattende samme, anvendelse af mus med cd300a-gen-mangel og anti-cd300a antistof |
WO2014073529A1 (fr) | 2012-11-07 | 2014-05-15 | 国立大学法人筑波大学 | MÉDICAMENT COMPRENANT UN MODULATEUR DE L'ACTIVITÉ D'UNE CELLULE EXPRIMANT LE CD300a ASSOCIÉE À UNE MALADIE ALLERGIQUE, SOURIS PRÉSENTANT UNE INACTIVATION DU GÈNE CD300a, ET UTILISATION DU MODULATEUR DE L'ACTIVITÉ DE LA CELLULE EXPRIMANT LE CD300a |
US9669070B2 (en) | 2013-09-17 | 2017-06-06 | The Feinstein Institute For Medical Research | Treatment and prevention of radiation injury using MFG-E8 |
WO2016179417A2 (fr) * | 2015-05-06 | 2016-11-10 | The University Of Utah Research Foundation | Administration d'exosomes de micro-arn |
EP4025237A1 (fr) | 2019-09-06 | 2022-07-13 | Novartis AG | Protéines de fusion thérapeutiques |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1004664A1 (fr) | 1998-11-24 | 2000-05-31 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Compositions et procédés utilisant la lactadhérine ou des dérivés de celle-ci |
EP1417229B1 (fr) * | 2001-08-17 | 2011-06-15 | Exothera L.L.C. | Procedes et composes pour le ciblage de proteines vers des exosomes |
JP4160292B2 (ja) * | 2001-11-20 | 2008-10-01 | 独立行政法人科学技術振興機構 | 生体内のアポトーシス細胞の除去促進剤及び除去阻害剤 |
US7354897B2 (en) * | 2002-06-07 | 2008-04-08 | Brigham & Women's Hospital, Inc. | Method and composition for inhibiting or slowing blood coagulation |
EP2215264B1 (fr) | 2007-11-15 | 2015-04-01 | The Feinstein Institute for Medical Research | Prévention et traitement d'inflammation et de lésion d'organe après ischémie/reperfusion en utilisant mfg-e8 |
WO2012149254A2 (fr) | 2011-04-28 | 2012-11-01 | The Feinstein Institute For Medical Research | Mfg-e8 et ses utilisations |
-
2006
- 2006-05-12 AU AU2006243905A patent/AU2006243905B2/en not_active Ceased
- 2006-05-12 CN CN2006800223836A patent/CN101203234B/zh not_active Expired - Fee Related
- 2006-05-12 WO PCT/US2006/018774 patent/WO2006122327A2/fr active Application Filing
- 2006-05-12 EP EP06784414.2A patent/EP1888096B1/fr not_active Not-in-force
- 2006-05-12 US US11/920,304 patent/US9321822B2/en not_active Expired - Fee Related
- 2006-05-12 CA CA2608271A patent/CA2608271C/fr active Active
Also Published As
Publication number | Publication date |
---|---|
WO2006122327A8 (fr) | 2007-05-24 |
US9321822B2 (en) | 2016-04-26 |
EP1888096B1 (fr) | 2017-12-27 |
AU2006243905A1 (en) | 2006-11-16 |
EP1888096A2 (fr) | 2008-02-20 |
CA2608271A1 (fr) | 2006-11-16 |
AU2006243905B2 (en) | 2011-09-01 |
US20090297498A1 (en) | 2009-12-03 |
WO2006122327A2 (fr) | 2006-11-16 |
EP1888096A4 (fr) | 2009-08-26 |
CN101203234B (zh) | 2012-10-10 |
WO2006122327A3 (fr) | 2007-12-13 |
CN101203234A (zh) | 2008-06-18 |
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