CA2576457A1 - Container system - Google Patents

Container system Download PDF

Info

Publication number
CA2576457A1
CA2576457A1 CA002576457A CA2576457A CA2576457A1 CA 2576457 A1 CA2576457 A1 CA 2576457A1 CA 002576457 A CA002576457 A CA 002576457A CA 2576457 A CA2576457 A CA 2576457A CA 2576457 A1 CA2576457 A1 CA 2576457A1
Authority
CA
Canada
Prior art keywords
bottle
tip
container system
neck
nozzle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002576457A
Other languages
French (fr)
Inventor
Scott J. Gerondale
Lon T. Spada
Paul T. Butorac
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allergan Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2576457A1 publication Critical patent/CA2576457A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D1/00Containers having bodies formed in one piece, e.g. by casting metallic material, by moulding plastics, by blowing vitreous material, by throwing ceramic material, by moulding pulped fibrous material, by deep-drawing operations performed on sheet material
    • B65D1/02Bottles or similar containers with necks or like restricted apertures, designed for pouring contents
    • B65D1/0223Bottles or similar containers with necks or like restricted apertures, designed for pouring contents characterised by shape
    • B65D1/023Neck construction
    • B65D1/0246Closure retaining means, e.g. beads, screw-threads
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D47/00Closures with filling and discharging, or with discharging, devices
    • B65D47/04Closures with discharging devices other than pumps
    • B65D47/06Closures with discharging devices other than pumps with pouring spouts or tubes; with discharge nozzles or passages
    • B65D47/18Closures with discharging devices other than pumps with pouring spouts or tubes; with discharge nozzles or passages for discharging drops; Droppers

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Ceramic Engineering (AREA)
  • Closures For Containers (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

A container system includes a squeeze bottle (10) of a specific volume having a neck (14) with an open end (16) and a medicament disposed within the bottle.
A tip (40) is provided which is insertable into the open end of the squeezable bottle and includes an internal tapered nozzle with the nozzle (46) having increased diameter toward a tip opening (50). A cap (80) is provided for removable attachment to the bottleneck for sealing the tip opening and a shoulder (50) formed in the bottle proximate the neck and disposed at an angle is provided in order to enhance bubbless flow of the medicament to the nozzle and facilitate tamper proof sealing of the cap.

Description

CONTAINER SYSTEM

The present invention generally relates to dropper bottles for dispensing of medicaments in droplet form and is more particularly directed to a container system for dispensing medicaments in less than 100 ml volumes with precise and uniform droplets.

Heretofore, dropwise container systems have typically included nozzles that are press fitted or otherwise inserted into a neck portion of a squeeze bottle.

In operation, squeeze bottle is inverted and manually squeezed by a user to dispense one or more drops through the nozzle. When medicament delivery when the medicament is fully dispensed, the container system is typically discarded.

Heretofore, resilient squeeze bottles often have substantial drop-to-drop volume variation when dispensing one or more drops in volumes of less than 100 ml, particularly in the 10 to 50 ml range.

This variation may be due to a bubble formation on interior surfaces of the bottle when the bottle is inverted so that drops, particularly eye drop medicati_on, are dispensed unevenly. Such adhered bubbles may be prevalent in square shoulder bottles and nozzles having areas which promote such bubble formation.

In addition, in view of the popularity of tamper proof bottles, it is desirable to facilitate the installation of such tamper proof systems.

Accordingly, there is a need for an improved container system for providing a uniform dropwise dispensing of medication.

SUMMARY OF THE INVENTION
A container system in accordance with the present invention generally includes a squeeze bottle of a specific volume having a neck with an open end and a medicament disposed within the bottle.

A tip fixable to the open end and includes internal tapered nozzle with the nozzle having increased diameter toward a tip opening.

A cap is provided for removably sealing the tip opening by attachment to the bottleneck.

A shoulder formed into the bottle proximate the neck and disposed at an angle of between about 45 and about 50 to a bottle centerline, is provided in order to both enhance bubbless flow of medicament to the nozzle and facilitate tamper proof sealing of the cap.
More particularly, the container system in accordance with the present invention may include a tip face surrounding the tip opening with a face width to control the uniformity and size of the droplets formed at the tip opening by squeezing of the bottle. In that regard, the face width may be between about 0.015 inches and about 0.060 inches with the specific volume of the bottle of between about 5 ml and about ml.

10 Preferably, the container system in accordance with the present invention provides droplet sizes between about 10 ml and about 50 ml.

BRIEF DESCRIPTION OF THE DRAWINGS
The advantages and features of the present invention will be better understood by the following description when considered in conjunction with the accompanying drawings in which:

Figure 1 is a side view of a 5 ml bottle in accordance with the present invention generally showing a neck with an open end and a shoulder formed into the bottle proximate the neck having an angle of between about 45 and 50 to a bottle centerline;

Figure 2 is a top view of the bottle shown in Figure 1;
Figure 3 is a cross sectional view of the bottle shown in Figure 2 taken along the line 3-3;

Figure 4 is an enlarged view of the bottleneck shown in Figures 1 and 3;

Figure 5 is a side view of a 10 ml bottle in accordance with the present invention;

Figure 6 is a top view of the bottle shown in Figure 5;
Figure 7 is a cross sectional view of the bottle shown in Figure 6 taken along the line 7-7;

Figure 8 is a side view of a 15 ml bottle in accordance with the present invention;

Figure 9 is a top view of the bottle shown in Figure 8;

Figure 10 is a cross sectional view taken along the line 10-10 of Figure 9;

Figure 11 is a side view of a tip in accordance with the present invention for insertion into the neck of the bottle of the present invention;

Figure 12 is a top view of the tip shown in Figure 11;
Figure 13 is a bottom view of the tip shown in Figure 11;
Figure 14 is a cross sectional view of the tip shown in Figure 13 taken along the line 14-14 and showing an internal nozzle and a face surrounding a tip opening;

Figure 15 is a side view of another tip in accordance with the present invention;

Figure 16 is a top view of the tip shown in Figure 15;
Figure 17 is a bottom view of the tip shown in Figure 15;
Figure 18 is a cross sectional view taken along the line 18-18 of Figure 17 showing a larger face surrounding a tip opening and an internal nozzle;

Figure 19 is a side view of a cap suitable for closure of the tips and bottles of the present invention;

Figure 20 is a top view of the cap shown in Figure 19;
Figure 21 is a bottom view of the cap shown in Figure 19;
Figure 22 is a cross sectional view of the cap taken along the line 20-22 of Figure 21; and Figure 23 is a side view of an assembled bottle and cap along with a taper proof seal.
DETAILED DESCRIPTION

With reference to Figures 1-3, there is shown a squeeze bottle 10 in accordance with the present invention having a neck 14 with an open end 16, see also Figure 4, which is an enlarged view of the neck 14 of the bottle 10 in accordance with the.present invention...

The bottle 10 may be formed from a suitable material, such as, for example, low-density polyethylene. The bottle 10 has a specific volume of 5 ml for containing a medicament 20 suitable for installation into an eye, not shown, by droplet formation, as will be hereinafter discussed in greater detail.

Figures 5-7 illustrate a bottle 24 in accordance with the present invention similar to that shown in Figures 1-3 with the bottle 24 having a specific volume of 10 ml and a neck 26 with an opening 28 therein.

Figures 8-10 illustrate a bottle 32 in accordance with the present invention which has a specific volume of 15 ml along with a neck 34, an opening 36.

As illustrated in Figures 12-14, a tip 40 in accordance with the present invention includes a base 42 sized for insertion into the bottleneck opening 16 and includes an internal tapered nozzle 46 having increased diameter toward a tip opening 50.
With reference again to Figures 1, 3, 5, 7, 8, and 10 each of the bottles 10, 24, 32 include shoulders 50, 52, 54 proximate necks 14, 26, 34 and disposed at an angle of between about 450 and about 500 to bottle centerlines 58, 60, 62, with an angle of 470 in 30 seconds being shown as a specific example.

This shoulder angle enhances bubbless flow of medicament 20 to the nozzle 46.

Figures 15-18 illustrate another nozzle 66 in accordance with the present invention including a base 68 sized for insertion into openings 16, 28, 34 and including an internal nozzle 70 similar to the nozzle 46 of the tip 40.

In comparing the tip 46 and 68, it can be seen that each include tip faces 72, 74 respectively surrounding openings 50, 80 respectively and having different surface areas, or face widths.

In the case of tip 40, the face width is about 0.015 inches while with the tip 66 the face width is about 0.060 inches. While only two tips 40, 66 being shown, it should be appreciated that similar tips having different tip face width dimensions are to be considered within the scope of the present invention and taken in combination with various bottle sizes, such as, for example, 5 ml, 10 ml, and 15 ml illustrated by the bottles 10, 24, 32 enable the control dropwise dispensing of medicament 20 with droplet sizes between less than l0p1 and about 50u1, preferably between about 8-12 pl. A greater face area provides for a larger droplet size.

With reference to Figures 19-22, there is shown a cap 80, formed from a suitable material having internal threads 82 for engaging a neck threads 84, see Figures 1 and 3 for example, and sealing the tip opening 50 with a convex surface 88.

An assembled container system 92 is shown in Figure 23 along with a tamper proof seal 96. Importantly, the sloped shoulder 50 facilitates the application of the seal 96 and enables a larger surface of the bottle 10 upper surface 100 to be sealed along with the cap 80 in order to provide a more secure tamper proof seal 96.

Although there has been hereinabove described a specific container system in accordance with the present invention for the purpose of illustrating the manner in which the invention may be used to advantage, it should be appreciated that the invention is not limited thereto. That is, the present invention may suitably comprise, consist of, or consist essentially of the recited elements. Further, the invention illustratively disclosed herein suitably may be practiced in the absence of any element which is not specifically disclosed herein. Accordingly, any and all modifications, variations or equivalent arrangements which may occur to those skilled in the art, should be considered to be within the scope of the present invention as defined in the appended claims.

Claims (8)

1. A container system comprising:
a squeeze bottle of a specific volume having a neck with an open end;
a medicament disposed in the bottle;
a tip insertable into said open end and having an internal tapered nozzle, the nozzle having increased diameter toward a tip opening;
a cap for removable attachment to the bottle neck for sealing said tip opening;
a shoulder formed into the bottle proximate said neck and disposed at an angle of between about 45° and about 50° to a bottle centerline in order to enhance bubbless flow of medicament to the nozzle and facilitate tamper proof sealing of said cap.
2. The container system according to claim 1 further comprises a tip face surrounding said tip opening with a face width to control uniformity and size of medicament droplets formed at said tip opening by squeezing of the bottle.
3. The container system according to claim 2 wherein said face width is between about 0.015 inches and about 0.060 inches and the specific volume is between about 5 ml and about 15 ml.
4. The container system according to claim 3 wherein the droplet size is between about 10µl and about 50µl.
5. A container system comprising:
a squeeze bottle of a specific volume having a neck with an open end;
a medicament disposed in the bottle;
a tip insertable into said open end and having an internal tapered nozzle, the nozzle having increased diameter toward a tip opening, said tip including a face surrounding said tip opening with a face width to control uniformity and size of medicament droplets formed at said tip opening by squeezing of the bottle; and a threaded cap for removable attachment to the bottleneck for sealing said tip opening.
6. The container system according to claim 5 wherein said face width is between about 0.015 inches and about 0.060 inches and the specific volume is between about 5 ml about 15 ml.
7. The container system according to claim 6 wherein the droplet size is between about 10µl and about 50µl.
8. The container system according to claim 5 further comprising a shoulder formed into the bottle proximate said neck and disposed at an angle of between about 45° and about 50° to a bottle centerline in order to enhance bubbless flow of medicament to the nozzle and facilitate tamper proof sealing of said cap to said neck.
CA002576457A 2004-08-11 2005-08-05 Container system Abandoned CA2576457A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/916,067 2004-08-11
US10/916,067 US20060032873A1 (en) 2004-08-11 2004-08-11 Container system
PCT/US2005/027872 WO2006020509A1 (en) 2004-08-11 2005-08-05 Container system

Publications (1)

Publication Number Publication Date
CA2576457A1 true CA2576457A1 (en) 2006-02-23

Family

ID=35447809

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002576457A Abandoned CA2576457A1 (en) 2004-08-11 2005-08-05 Container system

Country Status (7)

Country Link
US (1) US20060032873A1 (en)
EP (1) EP1776279A1 (en)
JP (1) JP2008509852A (en)
AU (1) AU2005273992A1 (en)
BR (1) BRPI0514302A (en)
CA (1) CA2576457A1 (en)
WO (1) WO2006020509A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8485378B2 (en) * 2009-04-08 2013-07-16 General Mills, Inc. Multi-container packages for dispensing liquid and dry food
WO2011143093A2 (en) * 2010-05-10 2011-11-17 Dr. Reddy's Laboratories Ltd. Ophthalmic dispensing device
CN106029513B (en) * 2014-02-13 2020-04-07 奥布里斯特封闭瑞士有限公司 Tamper evident closure
JP6305911B2 (en) * 2014-12-12 2018-04-04 株式会社無有 Perfume container
PE20160759A1 (en) 2015-06-09 2016-07-28 Gonzalez Sierra Andres Fernando IMPROVED DOSING SYSTEM
JP2020123597A (en) * 2017-05-30 2020-08-13 シャープ株式会社 Semiconductor device and manufacturing method of semiconductor device
US10723526B1 (en) 2019-03-29 2020-07-28 Chubby Gorilla, Inc. Bottle and cap arrangement

Family Cites Families (18)

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Publication number Priority date Publication date Assignee Title
US541314A (en) * 1895-06-18 carey
US2734665A (en) * 1956-02-14 Device for discharging liquids from
US3788528A (en) * 1971-08-23 1974-01-29 Ims Ltd Mini dropper
DE2355057A1 (en) * 1973-11-03 1975-05-07 Pfizer Gmbh Bottle dropper insert - has passage tapering outwards towards outlet for drop dispension of e.g. therapeutic fluids
US4584823A (en) * 1983-06-06 1986-04-29 Heinz Plastic Mold Co. Improved method and apparatus for blow molding in a single blow molding operation a controlled drop bottle
FR2622795B1 (en) * 1987-11-05 1994-03-25 Kerplas Snc DRIP DISPENSER
US4927062A (en) * 1988-09-22 1990-05-22 Walsh James W Precision micro-liter drop dispenser
FR2655623A1 (en) * 1989-12-08 1991-06-14 Merck Sharp & Dohme BOTTLE TIP FOR BOTTLE, PERMITTING THE INSTILLATION OF A LIQUID PRODUCT, ESPECIALLY A COLLAYER.
US5105993A (en) * 1989-12-29 1992-04-21 La Haye Laboratories, Inc. Disposable medical dispenser with a filtering dispenser nozzle
FR2696997B1 (en) * 1992-10-21 1995-01-06 Kerplas Snc Drip tip for bottle, and bottle equipped with such a tip.
JP2916097B2 (en) * 1995-02-13 1999-07-05 大東産業株式会社 Bottle sealing device for carbonated beverage bottles
JP3547939B2 (en) * 1997-06-10 2004-07-28 靜甲株式会社 Mounting method of cover of container cap
US6076709A (en) * 1998-05-04 2000-06-20 Dentsply Detrey G.M.B.H. Dental adhesive container dropping system
US6129248A (en) * 1998-09-18 2000-10-10 Hagele; James Precision release tip for medicinal liquid dropper
US6632202B1 (en) * 1999-03-16 2003-10-14 James Hagele Precision release eye dropper bottle
JP2002308307A (en) * 2001-04-18 2002-10-23 Yoshino Kogyosho Co Ltd Inside plug of container
JP2003221052A (en) * 2002-01-29 2003-08-05 Daipura Kk Liquid container
US8403176B2 (en) * 2003-01-22 2013-03-26 Allergan, Inc. Controlled drop dispensing container

Also Published As

Publication number Publication date
EP1776279A1 (en) 2007-04-25
BRPI0514302A (en) 2008-06-10
WO2006020509A1 (en) 2006-02-23
US20060032873A1 (en) 2006-02-16
AU2005273992A1 (en) 2006-02-23
JP2008509852A (en) 2008-04-03

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Legal Events

Date Code Title Description
FZDE Discontinued