CA2536069C - Utilisation de prophyrines vertes pour le diagnostic et la therapie oculaire - Google Patents
Utilisation de prophyrines vertes pour le diagnostic et la therapie oculaire Download PDFInfo
- Publication number
- CA2536069C CA2536069C CA002536069A CA2536069A CA2536069C CA 2536069 C CA2536069 C CA 2536069C CA 002536069 A CA002536069 A CA 002536069A CA 2536069 A CA2536069 A CA 2536069A CA 2536069 C CA2536069 C CA 2536069C
- Authority
- CA
- Canada
- Prior art keywords
- green
- light
- porphyrin
- choroidal
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
- A61K49/0036—Porphyrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/409—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Ophthalmology & Optometry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1994/002639 WO1995024930A1 (fr) | 1994-03-14 | 1994-03-14 | Utilisation de prophyrines vertes pour le diagnostic et la therapie oculaire |
| CA2185644A CA2185644C (fr) | 1994-03-14 | 1994-03-14 | Utilisation de prophyrines vertes pour le diagnostic et la therapie oculaire |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2185644A Division CA2185644C (fr) | 1994-03-14 | 1994-03-14 | Utilisation de prophyrines vertes pour le diagnostic et la therapie oculaire |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2536069A1 CA2536069A1 (fr) | 1995-09-21 |
| CA2536069C true CA2536069C (fr) | 2008-06-03 |
Family
ID=22242340
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2185644A Expired - Lifetime CA2185644C (fr) | 1994-03-14 | 1994-03-14 | Utilisation de prophyrines vertes pour le diagnostic et la therapie oculaire |
| CA002536069A Expired - Lifetime CA2536069C (fr) | 1994-03-14 | 1994-03-14 | Utilisation de prophyrines vertes pour le diagnostic et la therapie oculaire |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2185644A Expired - Lifetime CA2185644C (fr) | 1994-03-14 | 1994-03-14 | Utilisation de prophyrines vertes pour le diagnostic et la therapie oculaire |
Country Status (3)
| Country | Link |
|---|---|
| AU (1) | AU6813694A (fr) |
| CA (2) | CA2185644C (fr) |
| WO (1) | WO1995024930A1 (fr) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5770592A (en) * | 1991-11-22 | 1998-06-23 | Alcon Laboratories, Inc. | Prevention and treatment of ocular neovascularization using angiostatic steroids |
| JP3845469B2 (ja) | 1996-02-21 | 2006-11-15 | 明治製菓株式会社 | 眼底の新生血管の閉塞に用いる投与剤 |
| US5756541A (en) | 1996-03-11 | 1998-05-26 | Qlt Phototherapeutics Inc | Vision through photodynamic therapy of the eye |
| NZ331977A (en) * | 1996-03-26 | 2000-07-28 | Pharmacyclics Inc | Texaphyrin in photodynamic therapy of pigment-related lesions |
| US6043237A (en) * | 1996-12-10 | 2000-03-28 | Qlt Phototherapeutics, Inc. | Use of photodynamic therapy for prevention of secondary cataracts |
| US6270749B1 (en) | 1996-12-11 | 2001-08-07 | Pharmacyclics, Inc. | Use of Texaphyrin in ocular diagnosis and therapy |
| IL130246A0 (en) * | 1996-12-11 | 2000-06-01 | Pharmacyclics Inc | Use of a texaphyrin in the preparation of a medicament for use in ocular diagnosis and therapy |
| US6022526A (en) * | 1997-07-30 | 2000-02-08 | Pharmacyclics, Inc. | Use of texaphyrins in detection of melanin and melanin metabolites diagnostic of melanotic melanoma |
| US6117862A (en) * | 1998-10-09 | 2000-09-12 | Qlt, Inc. | Model and method for angiogenesis inhibition |
| IL126953A0 (en) | 1998-11-08 | 1999-09-22 | Yeda Res & Dev | Pharmaceutical compositions comprising porphyrins and some novel porphyrin derivatives |
| US6351663B1 (en) | 1999-09-10 | 2002-02-26 | Akorn, Inc. | Methods for diagnosing and treating conditions associated with abnormal vasculature using fluorescent dye angiography and dye-enhanced photocoagulation |
| US6944493B2 (en) | 1999-09-10 | 2005-09-13 | Akora, Inc. | Indocyanine green (ICG) compositions and related methods of use |
| AU7106400A (en) * | 1999-09-10 | 2001-04-10 | Akorn, Inc. | Fluorescent dye angiography and dye-enhanced photocoagulation |
| US6443976B1 (en) * | 1999-11-30 | 2002-09-03 | Akorn, Inc. | Methods for treating conditions and illnesses associated with abnormal vasculature |
| US20020049247A1 (en) * | 2000-01-12 | 2002-04-25 | Chen James C. | Novel treatment for eye disease |
| AU2001234979B2 (en) * | 2000-02-10 | 2006-07-27 | Massachusetts Eye And Ear Infirmary | Methods and compositions for treating conditions of the eye |
| AU2006203034B2 (en) * | 2000-02-10 | 2006-09-07 | Massachusetts Eye And Ear Infirmary | Methods and compositions for treating conditions of the eye |
| US7753943B2 (en) | 2001-02-06 | 2010-07-13 | Qlt Inc. | Reduced fluence rate PDT |
| CA2437557C (fr) * | 2001-02-06 | 2012-07-24 | Qlt Inc. | Therapie photodynamique a debit de fluence reduit permettant de traiter la neovascularisation choroidienne due a l'amd |
| IL161327A0 (en) * | 2001-11-09 | 2004-09-27 | Eyetech Pharmaceuticals | Methods for treating ocular neovascular diseases |
| US6723750B2 (en) | 2002-03-15 | 2004-04-20 | Allergan, Inc. | Photodynamic therapy for pre-melanomas |
| CA2500877A1 (fr) | 2002-10-03 | 2004-04-15 | Light Sciences Corporation | Systeme et procede d'excitation d'elements photosensibles des tissus de l'oeil |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5171749A (en) * | 1987-01-20 | 1992-12-15 | University Of British Columbia | Wavelength-specific cytotoxic agents |
| US5214036A (en) * | 1990-03-08 | 1993-05-25 | University Of British Columbia | Benzoporphyrin derivatives for photodynamic therapy |
-
1994
- 1994-03-14 CA CA2185644A patent/CA2185644C/fr not_active Expired - Lifetime
- 1994-03-14 WO PCT/US1994/002639 patent/WO1995024930A1/fr active Application Filing
- 1994-03-14 AU AU68136/94A patent/AU6813694A/en not_active Abandoned
- 1994-03-14 CA CA002536069A patent/CA2536069C/fr not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU6813694A (en) | 1995-10-03 |
| CA2185644A1 (fr) | 1995-09-21 |
| WO1995024930A1 (fr) | 1995-09-21 |
| CA2185644C (fr) | 2011-04-12 |
| CA2536069A1 (fr) | 1995-09-21 |
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| Date | Code | Title | Description |
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| EEER | Examination request | ||
| MKEX | Expiry |
Effective date: 20140314 |