CA2525550A1 - Acridone-derived compounds useful as antiretroviral agents - Google Patents

Acridone-derived compounds useful as antiretroviral agents Download PDF

Info

Publication number
CA2525550A1
CA2525550A1 CA002525550A CA2525550A CA2525550A1 CA 2525550 A1 CA2525550 A1 CA 2525550A1 CA 002525550 A CA002525550 A CA 002525550A CA 2525550 A CA2525550 A CA 2525550A CA 2525550 A1 CA2525550 A1 CA 2525550A1
Authority
CA
Canada
Prior art keywords
acridone
compounds useful
bond
double
derived compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002525550A
Other languages
French (fr)
Other versions
CA2525550C (en
Inventor
Christopher J. Michejda
Marek W. Cholody
William G. Rice
James A. Turpin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GOVERNMENT OF United States, REPRESENTED BY SECRE
Original Assignee
US Department of Health and Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Department of Health and Human Services filed Critical US Department of Health and Human Services
Priority claimed from CA002250863A external-priority patent/CA2250863C/en
Publication of CA2525550A1 publication Critical patent/CA2525550A1/en
Application granted granted Critical
Publication of CA2525550C publication Critical patent/CA2525550C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Viral replication inhibiting compounds of the general formula (II): (see formula I) wherein R is H, C1-C8 alkyl or a grouping which makes the composition function as a prodrug; R1 and R2 are independently -H, -OH, amino, C1-C8 alkylamino, C1-C8 dialkylamino, C1-C8 alkoxy, C1-C8 alkyl, C1-C8 haloalkyl or a halogen atom; n is 2 to 6; X and X' are independently -N or -NO2; Y and Y' are independently -N, -CH or -H; and each double dash represents a double bond or no bond, such that when X or X' is -N and Y or Y' is -CH or -N, the double dash is a double bond, and when X or X' is -N02 and Y or Y' is -H, the double dash is no bond.
CA002525550A 1996-04-12 1997-04-09 Acridone-derived compounds useful as antiretroviral agents Expired - Fee Related CA2525550C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US1532696P 1996-04-12 1996-04-12
US60/015,326 1996-04-12
US3505097P 1997-01-22 1997-01-22
US60/035,050 1997-01-22
CA002250863A CA2250863C (en) 1996-04-12 1997-04-09 Acridone-derived compounds useful as antineoplastic and antiretroviral agents

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA002250863A Division CA2250863C (en) 1996-04-12 1997-04-09 Acridone-derived compounds useful as antineoplastic and antiretroviral agents

Publications (2)

Publication Number Publication Date
CA2525550A1 true CA2525550A1 (en) 1997-10-23
CA2525550C CA2525550C (en) 2008-11-04

Family

ID=35589289

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002525550A Expired - Fee Related CA2525550C (en) 1996-04-12 1997-04-09 Acridone-derived compounds useful as antiretroviral agents

Country Status (1)

Country Link
CA (1) CA2525550C (en)

Also Published As

Publication number Publication date
CA2525550C (en) 2008-11-04

Similar Documents

Publication Publication Date Title
TR200000065T2 (en) Epothilone derivatives.
AU1824495A (en) Phosphonic diester derivative
EP0945452A4 (en) Sugar compounds, gelling agents, gelling agent compositions, processes for the preparation of them, and gel compositions
DK0892801T3 (en) Acridone-derived compounds useful as antineoplastic and antiretroviral agents
DK0918776T3 (en) Total synthesis of antitumor acylfulvenes
CA2242242A1 (en) Quinolonecarboxylic acid derivatives or salts thereof
CA2085345A1 (en) Pyrimidine nucleoside derivatives
DE69010100T2 (en) Pyrimidinyl herbicidal agent.
AU640645B2 (en) Pesticidal 1-arylimidazoles
IE811580L (en) Herbicidal compounds
ES2169220T3 (en) VITAMIN D3 DERIVATIVES WITH SUBSTITUTES IN POSITION 2.
CA2525550A1 (en) Acridone-derived compounds useful as antiretroviral agents
CA2337586A1 (en) Alkylation process and novel hydroxyphenylbenztriazoles
ATE198746T1 (en) PYRIMIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS
KR920012100A (en) Bisphosphonic acid derivatives, their preparation and uses
ATE105565T1 (en) PRADIMIC DERIVATIVES.
CA2137623A1 (en) Phenyl-substituted 1,4-dihydropyridines
CA2250863A1 (en) Acridone-derived compounds useful as antineoplastic and antiretroviral agents
ES2078337T3 (en) DERIVED FROM SULFONAMIDE AND PHARMACEUTICAL COMPOSITION CONTAINING IT.
ATE189813T1 (en) PROSTAGLANDIN-I ANALOGUE
ES2077697T3 (en) DERIVATIVES OF 1-PHENOXICARBONYL-2-PYRROLIDINONE AND NOOTROPIC AGENTS.
CA2037528A1 (en) 2-amino(fluoroalkoxy)pyrimidines and the preparation thereof
KR960004363A (en) Pyrimidine Acyclonucleoside Derivatives

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed