CA2465517C - Greffes a stent tubulaire extensible radialement eluant les medicaments - Google Patents
Greffes a stent tubulaire extensible radialement eluant les medicaments Download PDFInfo
- Publication number
- CA2465517C CA2465517C CA2465517A CA2465517A CA2465517C CA 2465517 C CA2465517 C CA 2465517C CA 2465517 A CA2465517 A CA 2465517A CA 2465517 A CA2465517 A CA 2465517A CA 2465517 C CA2465517 C CA 2465517C
- Authority
- CA
- Canada
- Prior art keywords
- carbons
- drug eluting
- stent
- stented graft
- graft
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/07—Stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/07—Stent-grafts
- A61F2002/075—Stent-grafts the stent being loosely attached to the graft material, e.g. by stitching
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Surgery (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Biomedical Technology (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
Abstract
L'invention porte sur des greffes à stent tubulaire éluant les médicaments, le stent étant recouvert d'un revêtement comprenant un composite constitué d'au moins un polymère bioérodable, acceptable d'un point de vue pharmaceutique, biocompatible et d'au moins une substance thérapeutique. Le polymère peut être un polyester. L'agent thérapeutique peut comprendre des vecteurs d'administration de gènes sélectifs tels que le sirolimus, l'actinomycine D et le paclitaxel. Les greffes à stent tubulaire ont, selon les formes d'exécution, un stent intégré et un stent intérieur, le stent pouvant soit s'autodilater, soit se dilater sous pression. Le stent peut également comprendre une pluralité d'éléments ayant chacun une forme linéaire ondulante créée dans une configuration généralement cylindrique, chaque élément étant raccordé à un élément adjacent par au moins un raccord linéaire. L'invention porte, en outre, sur un procédé de traitement des maladies cardio-vasculaires par implantation de la greffe à stent, et sur un article de fabrication comprenant un matériau de conditionnement et la greffe à stent.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US176501A | 2001-10-31 | 2001-10-31 | |
US10/001,765 | 2001-10-31 | ||
US09/997,829 | 2001-11-29 | ||
US09/997,829 US20020042645A1 (en) | 1996-07-03 | 2001-11-29 | Drug eluting radially expandable tubular stented grafts |
PCT/US2002/035065 WO2003037397A2 (fr) | 2001-10-31 | 2002-10-31 | Greffes a stent tubulaire extensible radialement eluant les medicaments |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2465517A1 CA2465517A1 (fr) | 2003-05-08 |
CA2465517C true CA2465517C (fr) | 2011-08-23 |
Family
ID=26669453
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2465517A Expired - Fee Related CA2465517C (fr) | 2001-10-31 | 2002-10-31 | Greffes a stent tubulaire extensible radialement eluant les medicaments |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1439868A2 (fr) |
JP (1) | JP2005507710A (fr) |
CA (1) | CA2465517C (fr) |
WO (1) | WO2003037397A2 (fr) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040024448A1 (en) * | 2002-08-05 | 2004-02-05 | Chang James W. | Thermoplastic fluoropolymer-coated medical devices |
JP4971580B2 (ja) * | 2003-06-05 | 2012-07-11 | テルモ株式会社 | ステントおよびステントの製造方法 |
ES2383374T3 (es) * | 2003-12-24 | 2012-06-20 | Novartis Ag | Dispositivos recubiertos con polímeros de PEC |
EP1811933B1 (fr) | 2004-09-28 | 2016-03-23 | Atrium Medical Corporation | Couche barriere |
US20060088596A1 (en) | 2004-09-28 | 2006-04-27 | Atrium Medical Corporation | Solubilizing a drug for use in a coating |
US9000040B2 (en) | 2004-09-28 | 2015-04-07 | Atrium Medical Corporation | Cross-linked fatty acid-based biomaterials |
US9012506B2 (en) | 2004-09-28 | 2015-04-21 | Atrium Medical Corporation | Cross-linked fatty acid-based biomaterials |
US9801982B2 (en) | 2004-09-28 | 2017-10-31 | Atrium Medical Corporation | Implantable barrier device |
US9278161B2 (en) | 2005-09-28 | 2016-03-08 | Atrium Medical Corporation | Tissue-separating fatty acid adhesion barrier |
US9427423B2 (en) | 2009-03-10 | 2016-08-30 | Atrium Medical Corporation | Fatty-acid based particles |
AU2006304590A1 (en) | 2005-10-15 | 2007-04-26 | Atrium Medical Corporation | Hydrophobic cross-linked gels for bioabsorbable drug carrier coatings |
US9492596B2 (en) | 2006-11-06 | 2016-11-15 | Atrium Medical Corporation | Barrier layer with underlying medical device and one or more reinforcing support structures |
EP2083875B1 (fr) | 2006-11-06 | 2013-03-27 | Atrium Medical Corporation | Filet chirurgical enrobe |
US20110038910A1 (en) | 2009-08-11 | 2011-02-17 | Atrium Medical Corporation | Anti-infective antimicrobial-containing biomaterials |
US10322213B2 (en) | 2010-07-16 | 2019-06-18 | Atrium Medical Corporation | Compositions and methods for altering the rate of hydrolysis of cured oil-based materials |
US9867880B2 (en) | 2012-06-13 | 2018-01-16 | Atrium Medical Corporation | Cured oil-hydrogel biomaterial compositions for controlled drug delivery |
WO2014031950A1 (fr) | 2012-08-24 | 2014-02-27 | Herskovic Arnold M | Dispositif et procédé visant à améliorer la curiethérapie |
US10543379B2 (en) | 2015-10-23 | 2020-01-28 | Boston Scientific Scimed, Inc. | Radioactive stents |
CN108013955B (zh) | 2016-11-04 | 2020-01-10 | 先健科技(深圳)有限公司 | 血管支架 |
US20210121180A1 (en) * | 2019-10-24 | 2021-04-29 | Atrium Medical Corporation | Endovascular fixation device |
CN117838403A (zh) * | 2022-09-30 | 2024-04-09 | 深圳市先健纬康科技有限公司 | 血管支架 |
CN115671407B (zh) * | 2022-10-25 | 2024-01-30 | 赛诺神畅医疗科技有限公司 | 一种自膨式药物洗脱支架***及其制备方法 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4131648A (en) * | 1975-01-28 | 1978-12-26 | Alza Corporation | Structured orthoester and orthocarbonate drug delivery devices |
US5797870A (en) * | 1995-06-07 | 1998-08-25 | Indiana University Foundation | Pericardial delivery of therapeutic and diagnostic agents |
US5928279A (en) * | 1996-07-03 | 1999-07-27 | Baxter International Inc. | Stented, radially expandable, tubular PTFE grafts |
US6623521B2 (en) * | 1998-02-17 | 2003-09-23 | Md3, Inc. | Expandable stent with sliding and locking radial elements |
US6224626B1 (en) * | 1998-02-17 | 2001-05-01 | Md3, Inc. | Ultra-thin expandable stent |
JP2002534165A (ja) * | 1998-12-31 | 2002-10-15 | アンジオテック ファーマシューティカルズ,インコーポレイテッド | 生物活性被覆を備えたステント移植片 |
US6241719B1 (en) * | 1999-05-13 | 2001-06-05 | Micro Therapeutics, Inc. | Method for forming a radioactive stent |
AU2001286940A1 (en) * | 2000-09-22 | 2002-04-02 | Kensey Nash Corporation | Drug delivering prostheses and methods of use |
US6254632B1 (en) * | 2000-09-28 | 2001-07-03 | Advanced Cardiovascular Systems, Inc. | Implantable medical device having protruding surface structures for drug delivery and cover attachment |
-
2002
- 2002-10-31 WO PCT/US2002/035065 patent/WO2003037397A2/fr active Application Filing
- 2002-10-31 JP JP2003539736A patent/JP2005507710A/ja active Pending
- 2002-10-31 EP EP02780558A patent/EP1439868A2/fr not_active Withdrawn
- 2002-10-31 CA CA2465517A patent/CA2465517C/fr not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP2005507710A (ja) | 2005-03-24 |
WO2003037397A3 (fr) | 2003-09-18 |
EP1439868A2 (fr) | 2004-07-28 |
CA2465517A1 (fr) | 2003-05-08 |
WO2003037397A2 (fr) | 2003-05-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |
Effective date: 20171031 |