CA2461026A1 - Sensor for anions in solution based on a molecularly imprinted polymer - Google Patents

Sensor for anions in solution based on a molecularly imprinted polymer Download PDF

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Publication number
CA2461026A1
CA2461026A1 CA002461026A CA2461026A CA2461026A1 CA 2461026 A1 CA2461026 A1 CA 2461026A1 CA 002461026 A CA002461026 A CA 002461026A CA 2461026 A CA2461026 A CA 2461026A CA 2461026 A1 CA2461026 A1 CA 2461026A1
Authority
CA
Canada
Prior art keywords
anions
molecularly imprinted
sensor
solution based
imprinted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002461026A
Other languages
French (fr)
Other versions
CA2461026C (en
Inventor
George M. Murray
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johns Hopkins University
Original Assignee
The Johns Hopkins University
George M. Murray
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Johns Hopkins University, George M. Murray filed Critical The Johns Hopkins University
Publication of CA2461026A1 publication Critical patent/CA2461026A1/en
Application granted granted Critical
Publication of CA2461026C publication Critical patent/CA2461026C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G01N2021/7706—Reagent provision
    • G01N2021/772—Tip coated light guide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2600/00—Assays involving molecular imprinted polymers/polymers created around a molecular template

Abstract

Devices for measuring and detecting a wide variety of analytes, including polyatomic anions, such as organophosphorus pesticides and nerve agents are provided. The devices function by selectively binding an analyte to a luminescent functionality-imprinted copolymer. The copolymers possess a securely bound luminescent lanthanide ion, such as Eu3+, in a coordination complex that has been imprinted to bind the chemical functionality. Also provided are methods for producing the lanthanide-containing molecularly imprinted polymers of the invention.
CA002461026A 2001-10-16 2002-10-16 Sensor for anions in solution based on a molecularly imprinted polymer Expired - Fee Related CA2461026C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US32965201P 2001-10-16 2001-10-16
US60/329,652 2001-10-16
PCT/US2002/033167 WO2003034043A2 (en) 2001-10-16 2002-10-16 Molecularly imprinted polymer solution anion sensor

Publications (2)

Publication Number Publication Date
CA2461026A1 true CA2461026A1 (en) 2003-04-24
CA2461026C CA2461026C (en) 2009-09-08

Family

ID=23286404

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002461026A Expired - Fee Related CA2461026C (en) 2001-10-16 2002-10-16 Sensor for anions in solution based on a molecularly imprinted polymer

Country Status (5)

Country Link
EP (1) EP1436599A2 (en)
JP (1) JP2005506536A (en)
AU (1) AU2002356815B2 (en)
CA (1) CA2461026C (en)
WO (1) WO2003034043A2 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA012141B1 (en) * 2003-11-21 2009-08-28 Бейкер Хьюз Инкорпорейтед Method and apparatus downhole fluid analysis using molecularly imprinted polymers
AU2003296866A1 (en) * 2003-12-31 2005-07-21 Council Of Scientific And Industrial Research Synthesis of ion imprinted polymer particles
US6960645B2 (en) 2004-03-26 2005-11-01 Council Of Scientific And Industrial Research Synthesis of ion imprinted polymer particles
CA2560384C (en) * 2004-04-08 2012-12-04 The Johns Hopkins University Processable molecularly imprinted polymers
WO2005108443A1 (en) * 2004-05-07 2005-11-17 Japan Science And Technology Agency Molecule recognition polymer enabling reconstruction of recognition field for target molecule and method of producing the same
WO2006076430A1 (en) * 2005-01-14 2006-07-20 Texas Tech University Nerve agent detection method and device
EP1896690B1 (en) 2005-05-24 2011-12-14 Baker Hughes Incorporated A method and apparatus for reservoir characterization using photoacoustic spectroscopy
EP2313761A4 (en) * 2008-07-28 2013-08-14 Sensors For Med & Science Inc Systems and methods for optical measurement of analyte concentration
CN104629755A (en) * 2015-02-02 2015-05-20 苏州亚科化学试剂股份有限公司 Luminal powder agent for detecting composite organophosphorus pesticide residue and preparation method of luminal powder agent
JP6215900B2 (en) * 2015-12-03 2017-10-18 株式会社東芝 Compound detection method and detection apparatus
JP6483215B2 (en) * 2017-09-21 2019-03-13 株式会社東芝 Compound detector
CN110186884B (en) * 2019-07-09 2022-02-11 南昌大学 Visual molecularly imprinted nanosensor and preparation and application thereof
WO2021127105A1 (en) 2019-12-17 2021-06-24 Georgia Tech Research Corporation Polymer based sensors for detecting agricultural analytes and methods of making same
CN112900150A (en) * 2021-01-26 2021-06-04 新疆维吾尔自治区产品质量监督检验研究院 Molecular imprinting rare earth double-fluorescence sensing test paper and preparation method thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998022795A1 (en) * 1996-11-22 1998-05-28 The Regents Of The University Of California Chemical microsensors for detection of explosives and chemical warfare agents

Also Published As

Publication number Publication date
JP2005506536A (en) 2005-03-03
EP1436599A2 (en) 2004-07-14
CA2461026C (en) 2009-09-08
WO2003034043A3 (en) 2003-07-31
AU2002356815B2 (en) 2008-05-08
WO2003034043A2 (en) 2003-04-24

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Effective date: 20181016