CA2444377A1 - Procede d'injection intradermique de substances - Google Patents

Procede d'injection intradermique de substances Download PDF

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Publication number
CA2444377A1
CA2444377A1 CA002444377A CA2444377A CA2444377A1 CA 2444377 A1 CA2444377 A1 CA 2444377A1 CA 002444377 A CA002444377 A CA 002444377A CA 2444377 A CA2444377 A CA 2444377A CA 2444377 A1 CA2444377 A1 CA 2444377A1
Authority
CA
Canada
Prior art keywords
substance
skin
needle
needle cannula
tip
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002444377A
Other languages
English (en)
Other versions
CA2444377C (fr
Inventor
Paul G. Alchas
Philippe Emile Fernand Laurent
John A. Mikszta
Jason Brent Alarcon
Phil G. Green
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2444377A1 publication Critical patent/CA2444377A1/fr
Application granted granted Critical
Publication of CA2444377C publication Critical patent/CA2444377C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/46—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for controlling depth of insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3103—Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
    • A61M2005/3104—Caps for syringes without needle

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

L'invention concerne un procédé de préparation d'une injection intradermique au moyen d'un dispositif d'administration de médicament contenant la substance à injecter. L'invention concerne aussi un dispositif destiné à mettre en oeuvre le procédé comportant une canule à aiguille qui possède une pointe avant et une portion de limitation comportant une surface de mise en prise avec la peau qui entoure la canule à aiguille. Cette canule à aiguille est en communication fluidique avec la substance et la pointe de la canule à aiguille s'étend au delà de la surface de mise en prise avec la peau à une distance approximativement comprise entre 0,5 et 3 mm. Selon l'invention, elle comporte un angle d'orientation fixe par rapport au plan de la surface de mise en prise avec la peau. Cette surface de mise en prise avec la peau limite la pénétration de la pointe de l'aiguille dans la peau de manière que la substance puisse être expulsée à travers la pointe de l'aiguille dans la couche dermique. De préférence, l'angle d'orientation fixe de la canule à aiguille est perpendiculaire à la surface de la peau, et la surface de mise en prise avec la peau est généralement plate.
CA2444377A 2001-04-13 2001-04-13 Procede d'injection intradermique de substances Expired - Lifetime CA2444377C (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2001/012251 WO2002083216A1 (fr) 2001-04-13 2001-04-13 Procede d'injection intradermique de substances

Publications (2)

Publication Number Publication Date
CA2444377A1 true CA2444377A1 (fr) 2002-10-24
CA2444377C CA2444377C (fr) 2014-09-02

Family

ID=21742508

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2444377A Expired - Lifetime CA2444377C (fr) 2001-04-13 2001-04-13 Procede d'injection intradermique de substances

Country Status (7)

Country Link
EP (1) EP1381415A1 (fr)
JP (1) JP2004528896A (fr)
CN (1) CN1520320A (fr)
BR (1) BR0116973A (fr)
CA (1) CA2444377C (fr)
MX (1) MXPA03009369A (fr)
WO (1) WO2002083216A1 (fr)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0210628A (pt) * 2001-06-29 2004-08-10 Becton Dickinson Co Liberação intradérmica de vacinas e agentes terapêuticos genéticos via microcânula
KR20040103930A (ko) 2002-02-11 2004-12-09 앤태어스 파머, 인코퍼레이티드 피내 주사기
JP2007517768A (ja) * 2003-05-06 2007-07-05 ベクトン・ディキンソン・アンド・カンパニー インスリンの薬物動態を変化させる方法
CA2595730C (fr) 2005-01-24 2014-10-07 Antares Pharma, Inc. Injecteur a pression pour seringue assistee par aiguille preremplie
CN101421002B (zh) 2006-02-09 2012-09-26 阿德兰斯研究学院有限公司 用于将流体和材料输送到对象中的装置和方法
WO2007131025A1 (fr) 2006-05-03 2007-11-15 Antares Pharma, Inc. Injecteur à dosage réglable
US8251947B2 (en) 2006-05-03 2012-08-28 Antares Pharma, Inc. Two-stage reconstituting injector
US20080312661A1 (en) * 2007-06-12 2008-12-18 Downer David A Lens Injector Lumen Tip for Wound Assisted Delivery
CN101938956B (zh) 2008-02-07 2013-12-18 爱尔康公司 一种用于晶状体输送***的盒
CA2718053C (fr) 2008-03-10 2016-09-27 Antares Pharma, Inc. Dispositif de securite pour injecteur
WO2010017285A2 (fr) 2008-08-05 2010-02-11 Antares Pharma, Inc. Injecteur à dosage multiple
BRPI0922213B8 (pt) * 2008-12-08 2021-06-22 Program For Appropriate Tech In Health alinhamento de uma agulha em um dispositivo de injeção intradérmica
TWI449551B (zh) * 2009-01-30 2014-08-21 Terumo Corp 注射針組合體以及藥劑注射裝置
US8579865B2 (en) 2009-03-20 2013-11-12 Antares Pharma, Inc. Hazardous agent injection system
US9089655B2 (en) 2009-07-23 2015-07-28 Sid Technologies, Llc Intradermal injection adapter
EP2489379B1 (fr) 2011-01-21 2020-09-23 SID Technologies, LLC Adaptateur de stylo intradermique
US8496619B2 (en) 2011-07-15 2013-07-30 Antares Pharma, Inc. Injection device with cammed ram assembly
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
ES2562838T3 (es) * 2012-01-31 2016-03-08 Trichoscience Innovations Inc. Dispositivos de inyección
US9486583B2 (en) 2012-03-06 2016-11-08 Antares Pharma, Inc. Prefilled syringe with breakaway force feature
EP2833944A4 (fr) 2012-04-06 2016-05-25 Antares Pharma Inc Administration par injection par jet assistée par une aiguille de compositions de testostérone
US9364610B2 (en) 2012-05-07 2016-06-14 Antares Pharma, Inc. Injection device with cammed ram assembly
US9463089B2 (en) 2012-05-21 2016-10-11 Novartis Ag Plunger system for intraocular lens surgery
EP2953667B1 (fr) 2013-02-11 2019-10-23 Antares Pharma, Inc. Dispositif d'injection à jet assistée par aiguille ayant une force de déclenchement réduite
EP3572108A1 (fr) 2013-03-11 2019-11-27 Antares Pharma, Inc. Injecteur de dose avec système à pignon
WO2014165136A1 (fr) 2013-03-12 2014-10-09 Antares Pharma, Inc. Seringues pré-remplies à volume constant et leurs trousses
DK2968071T3 (da) * 2013-03-15 2021-11-08 Rani Therapeutics Llc Enhed til oral levering af terapeutiske forbindelser
EP2979716B1 (fr) * 2013-03-26 2019-08-21 Terumo Kabushiki Kaisha Capuchon élastique et ensemble seringue doté de celui-ci
US9474865B2 (en) 2013-04-25 2016-10-25 West Pharmaceutical Services, Inc. Needle shield for disposable syringe with annular ring
EP3041505A4 (fr) 2013-09-05 2017-04-19 Merck Sharp & Dohme Corp. Procédés d'immunisation par l'antigène du virus varicelle-zona
TWI689326B (zh) 2014-08-06 2020-04-01 加拿大商複製細胞生命科學公司 注射裝置
US10588780B2 (en) 2015-03-04 2020-03-17 Alcon Inc. Intraocular lens injector
US10925639B2 (en) 2015-06-03 2021-02-23 Intarcia Therapeutics, Inc. Implant placement and removal systems
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
US11000367B2 (en) 2017-01-13 2021-05-11 Alcon Inc. Intraocular lens injector
CN107287268A (zh) * 2017-06-16 2017-10-24 南京佰泰克生物技术有限公司 一种增强hiv‑1核酸疫苗免疫原性的佐剂
USD933219S1 (en) 2018-07-13 2021-10-12 Intarcia Therapeutics, Inc. Implant removal tool and assembly

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2664086A (en) * 1950-08-15 1953-12-29 Gerald O Transue Automatic injector for hypodermic needles
GB725024A (en) * 1952-11-07 1955-03-02 Lilly Co Eli Improvements in or relating to closure member for a syringe
US5279586A (en) 1992-02-04 1994-01-18 Becton, Dickinson And Company Reusable medication delivery pen
US5373684A (en) 1992-12-14 1994-12-20 Mallinckrodt Medical, Inc. Process and apparatus used in producing prefilled, sterile delivery devices
US5620425A (en) 1993-11-03 1997-04-15 Bracco International B.V. Method for the preparation of pre-filled plastic syringes
US5597530A (en) 1994-08-18 1997-01-28 Abbott Laboratories Process for prefilling and terminally sterilizing syringes
US5537042A (en) 1994-11-18 1996-07-16 Eldec Corporation Method and system for unobtrusively measuring physical properties in electrochemical processes
ATE265873T1 (de) * 1997-11-19 2004-05-15 B D Medico S A R L Nadelanordnung
EP1061974A1 (fr) 1998-03-13 2000-12-27 Becton, Dickinson and Company Procede de fabrication, de remplissage et de conditionnement de contenants medicaux
WO2000009135A1 (fr) 1998-08-14 2000-02-24 Toray Industries, Inc. Agents de protection des cellules péridermiques
US6494865B1 (en) * 1999-10-14 2002-12-17 Becton Dickinson And Company Intradermal delivery device including a needle assembly

Also Published As

Publication number Publication date
CN1520320A (zh) 2004-08-11
CA2444377C (fr) 2014-09-02
EP1381415A1 (fr) 2004-01-21
BR0116973A (pt) 2004-10-13
JP2004528896A (ja) 2004-09-24
MXPA03009369A (es) 2004-01-29
WO2002083216A1 (fr) 2002-10-24

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Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20210413