CA2441006A1 - Methodes et materiels se rapportant a des polypeptides et a des polynucleotides apparentes a la fibuline - Google Patents

Methodes et materiels se rapportant a des polypeptides et a des polynucleotides apparentes a la fibuline Download PDF

Info

Publication number
CA2441006A1
CA2441006A1 CA002441006A CA2441006A CA2441006A1 CA 2441006 A1 CA2441006 A1 CA 2441006A1 CA 002441006 A CA002441006 A CA 002441006A CA 2441006 A CA2441006 A CA 2441006A CA 2441006 A1 CA2441006 A1 CA 2441006A1
Authority
CA
Canada
Prior art keywords
polypeptide
polynucleotide
protein
cells
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002441006A
Other languages
English (en)
Inventor
Shubhada D. Godbole
Bryan J. Boyle
Matthew C. Arterburn
Chenghua Liu
Y. Tom Tang
Radoje T. Drmanac
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nuvelo Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2441006A1 publication Critical patent/CA2441006A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/11—Compounds covalently bound to a solid support
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Cette invention concerne de nouveaux polynucléotides, ainsi que des polypeptides codés par ces polynucléotides, et leurs mutants ou variants, qui correspondent à un nouveau polypeptide humain sécrété apparenté à la fibuline. Ces polynucléotides comprennent des séquences d'acide nucléique isolées d'une bibliothèque d'ADNc préparée à partir de l'ARNm de la glande thyroïde humaine (Clontech) (SEQ ID NO: 1). D'autres aspects de l'invention incluent des vecteurs contenant des processus destinés à produire de nouveaux polypeptides humains sécrétés apparentés à la fibuline, et des anticorps spécifiques desdits polypeptides.
CA002441006A 2001-03-08 2002-03-08 Methodes et materiels se rapportant a des polypeptides et a des polynucleotides apparentes a la fibuline Abandoned CA2441006A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80270401A 2001-03-08 2001-03-08
US09/802,704 2001-03-08
PCT/US2002/007282 WO2002072138A1 (fr) 2001-03-08 2002-03-08 Methodes et materiels se rapportant a des polypeptides et a des polynucleotides apparentes a la fibuline

Publications (1)

Publication Number Publication Date
CA2441006A1 true CA2441006A1 (fr) 2002-09-19

Family

ID=25184475

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002441006A Abandoned CA2441006A1 (fr) 2001-03-08 2002-03-08 Methodes et materiels se rapportant a des polypeptides et a des polynucleotides apparentes a la fibuline

Country Status (3)

Country Link
EP (1) EP1365801A4 (fr)
CA (1) CA2441006A1 (fr)
WO (1) WO2002072138A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1395669T3 (da) 2001-01-26 2009-11-16 Selexis Sa Matriks bindingsregioner og fremgangsmåder til anvendelse af disse
AU2004284220B2 (en) 2003-10-24 2010-10-14 Selexis S.A. High efficiency gene transfer and expression in mammalian cells by a multiple transfection procedure of matrix attachment region sequences
EP1910416B1 (fr) 2005-07-22 2014-09-10 Erasmus University Medical Center Rotterdam Modele animal non humain pour maladie cardio-vasculaire caracterisee par un gene de fibuline-4 fragmente
WO2015138411A1 (fr) * 2014-03-10 2015-09-17 The Brigham And Women's Hospital, Inc. Anticorps anti-fibuline et leurs utilisations

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5204259A (en) * 1988-05-06 1993-04-20 Pharmacia Genetic Engineering, Inc. Methods and systems for producing HIV antigens
AU6299390A (en) * 1989-08-18 1991-04-03 American National Red Cross, The Fibulin
WO1997038014A1 (fr) * 1996-04-04 1997-10-16 Amgen Inc. Compositions pharmaceutiques renfermant la fibuline et procedes connexes
EP1012335A4 (fr) * 1997-08-15 2004-06-09 Hyseq Inc Procedes et compositions de detection ou de quantification d'especes d'acides nucleiques
US6593104B1 (en) * 1999-02-12 2003-07-15 University Of Iowa Research Foundation Macular degeneration diagnostics and therapeutics
WO2000058473A2 (fr) * 1999-03-31 2000-10-05 Curagen Corporation Acides nucleiques comprenant des phases de lecture ouverte codant des polypeptides; «orfx»
CA2389305A1 (fr) * 1999-11-05 2001-05-17 Human Genome Sciences, Inc. 28 proteines secretees humaines
AU2001259063A1 (en) * 2000-04-12 2001-10-30 Human Genome Sciences, Inc. Albumin fusion proteins

Also Published As

Publication number Publication date
EP1365801A1 (fr) 2003-12-03
EP1365801A4 (fr) 2004-10-13
WO2002072138A1 (fr) 2002-09-19

Similar Documents

Publication Publication Date Title
US6610536B2 (en) Nucleic acids and polypeptides
US7981413B2 (en) Methods and compositions concerning antibodies that bind CD84-like polypeptides
US20070049743A1 (en) Novel nucleic acids and polypeptides
US20020150898A1 (en) Novel nucleic acids and polypeptides
AU2001233003B2 (en) Methods and materials relating to leukocyte immunoglobulin receptor-like (lir-like) polypeptides and polynucleotides
EP1574520A2 (fr) Polypeptides et polynucléotides ressemblant à la molécule de guidage neuronale ainsi que méthodes et matériaux dérivés
AU2001255214B2 (en) Method and materials relating to insulin-like growth factor binding protein-like polypeptides and polynucleotides
AU2001255214A1 (en) Method and materials relating to insulin-like growth factor binding protein-like polypeptides and polynucleotides
CA2441006A1 (fr) Methodes et materiels se rapportant a des polypeptides et a des polynucleotides apparentes a la fibuline
US20030144491A1 (en) Methods and materials relating to cadherin-like polypeptides and polynucleotides
US20050175994A1 (en) Methods and materials relating to prothrombinase-like polypeptides and polynucleotides
WO2001053456A9 (fr) Procedes et substances relatifs a des polypeptides de type prothrombinase et a des polynucleotides
US20030100746A1 (en) Methods and materials relating to fibulin-like polypeptides and polynucleotides
US20040122220A1 (en) Methods and materials relating to preadipocyte factor-1-like (pref-1-like) polypeptides and polynucleotides
CA2398548A1 (fr) Procedes et substances relatifs a des polypeptides de type antigene carcino-embryonnaire (cea) et a des polynucleotides
WO2001057261A9 (fr) Procedes et matieres lies a des polypeptides et des polynucleotides du type proteine repetee riche en leucine (du type proteine lrr)
US20040106116A1 (en) Methods and materials relating to hematopoietic cytokine-like polypeptides and polynucleotides
WO2001057260A1 (fr) Procedes et materiaux concernant des polypeptides semblables au recepteur de destructeurs et polynucleotides
CA2398215A1 (fr) Methodes et materiaux associes a des polypeptides et des polynucleotides du type facteur-1 des preadipocytes (du type pref-1)
US20040236090A1 (en) Methods and materials relating to fibulin like polypeptides and polynucleotides
US20040116683A1 (en) Methods and materials relating to neurotrimin-like polypeptides and polynucleotides
US20040072173A1 (en) Methods and materials relating to leucine-rich repeat protein-like (lrr protein-like) polypeptides and polynucleotides
WO2001057267A9 (fr) Methodes et matieres relatives aux polynucleotides et polypeptides du domaine cub
WO2001053466A1 (fr) Procedes et substances relatifs a des polypeptides de type semaphorine et a des polynucleotides
CA2395763A1 (fr) Procedes et substances relatifs a des polypeptides de type semaphorine et a des polynucleotides

Legal Events

Date Code Title Description
FZDE Discontinued