CA2392109A1 - Proteines de recepteurs mammaliens, reactifs et procedes s'y rapportant - Google Patents

Proteines de recepteurs mammaliens, reactifs et procedes s'y rapportant Download PDF

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Publication number
CA2392109A1
CA2392109A1 CA002392109A CA2392109A CA2392109A1 CA 2392109 A1 CA2392109 A1 CA 2392109A1 CA 002392109 A CA002392109 A CA 002392109A CA 2392109 A CA2392109 A CA 2392109A CA 2392109 A1 CA2392109 A1 CA 2392109A1
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CA
Canada
Prior art keywords
ser
leu
pro
glu
gly
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002392109A
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English (en)
Inventor
Daniel M. Gorman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2392109A1 publication Critical patent/CA2392109A1/fr
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention concerne des acides nucléiques codant des récepteurs mammaliens, notamment de primates, des protéines de récepteurs purifiées, et certains de leurs fragments. L'invention concerne également des anticorps, aussi bien polyclonaux que monoclonaux. L'invention concerne enfin des modes d'utilisation de ces compositions à des fins tant de diagnostics que thérapeutiques.
CA002392109A 1999-11-18 2000-11-16 Proteines de recepteurs mammaliens, reactifs et procedes s'y rapportant Abandoned CA2392109A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US44306099A 1999-11-18 1999-11-18
US09/443,060 1999-11-18
US17032099P 1999-12-13 1999-12-13
US60/170,320 1999-12-13
PCT/US2000/031363 WO2001036467A2 (fr) 1999-11-18 2000-11-16 Proteines de recepteurs mammaliens, reactifs et procedes s'y rapportant

Publications (1)

Publication Number Publication Date
CA2392109A1 true CA2392109A1 (fr) 2001-05-25

Family

ID=26865975

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002392109A Abandoned CA2392109A1 (fr) 1999-11-18 2000-11-16 Proteines de recepteurs mammaliens, reactifs et procedes s'y rapportant

Country Status (6)

Country Link
EP (1) EP1230368A2 (fr)
JP (1) JP2003523179A (fr)
AU (1) AU1919201A (fr)
CA (1) CA2392109A1 (fr)
MX (1) MXPA02005058A (fr)
WO (1) WO2001036467A2 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7198789B2 (en) 1998-03-17 2007-04-03 Genetics Institute, Llc Methods and compositions for modulating interleukin-21 receptor activity
US6057128A (en) 1998-03-17 2000-05-02 Genetics Institute, Inc. MU-1, member of the cytokine receptor family
AU2253301A (en) 1999-12-03 2001-06-12 Zymogenetics Inc. Human cytokine receptor
US20030170823A1 (en) 1999-12-23 2003-09-11 Presnell Scott R. Novel cytokine ZCYTO18
AU2001290524A1 (en) 2000-08-08 2002-02-18 Zymogenetics Inc. Soluble zcytor 11 cytokine receptors
US7268223B2 (en) 2000-09-22 2007-09-11 Wyeth Isolated nucleic acid molecules which encode a soluble IL-TIF receptor or binding protein which binds to IL-TIF/IL-22, and uses thereof
US7094570B2 (en) 2003-03-11 2006-08-22 Ludwig Institute For Cancer Research Isolated nucleic acid molecules which encode a soluble IL-TIF/IL-22 receptor or binding protein which binds to IL-TIF/IL-22, and uses thereof
EP1191035A3 (fr) * 2000-09-25 2002-04-17 Schering Aktiengesellschaft Trois membres de la famille des recepteurs de la cytokine de classe II
US7176180B2 (en) 2001-01-12 2007-02-13 Wyeth Type 2 cytokine receptor and nucleic acids encoding same
CA2439636A1 (fr) * 2001-03-02 2002-09-12 Zymogenetics, Inc. Recepteur de cytokine murin
WO2002077174A2 (fr) * 2001-03-27 2002-10-03 Zymogenetics, Inc. Recepteur de cytokine humaine
EP1546358A4 (fr) 2002-03-22 2006-06-07 Zymogenetics Inc Anticorps anti-il-tif et leurs methodes d'utilisation dans une inflammation
GB0216661D0 (en) * 2002-07-17 2002-08-28 Ares Trading Sa Protein
BRPI0408315A (pt) 2003-03-14 2006-03-07 Wyeth Corp anticorpo isolado, composição farmacêutica, ácido nucleico isolado, vetor de expressão, célula hospedeira, métodos de produzir um anticorpo, de gerar um anticorpo ou fragmento de ligação de antìgeno, de regular uma resposta imune, de tratar ou prevenir um distúrbio associado com célula imune em um paciente, de tratar ou prevenir um distúrbio hiperproliferativo em um paciente, e, kit de diagnóstico
WO2004085476A2 (fr) 2003-03-24 2004-10-07 Zymogenetics, Inc. Anticorps anti-il-22ra et leurs partenaires de liaison, methodes d'utilisation de ces derniers dans les cas d'inflammation
EP1812476B1 (fr) 2004-10-22 2010-07-21 ZymoGenetics, Inc. Anticorps anti-il-22ra et partenaires de liaison et methodes d'utilisation de ces anticorps et de ces partenaires de liaison pour le traitement de maladies inflammatoires
CN105859886A (zh) 2005-12-02 2016-08-17 健泰科生物技术公司 牵涉与il-22和il-22r结合的抗体的组合物和方法
WO2023187201A1 (fr) * 2022-04-01 2023-10-05 Universite Catholique De Louvain Fragments du récepteur de la thrombopoïétine et leurs utilisations

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2011450C (fr) * 1989-03-07 2002-06-04 Tadatsugu Taniguchi Chaine beta recombinante du recepteur d'il-2
US5945511A (en) * 1997-02-20 1999-08-31 Zymogenetics, Inc. Class II cytokine receptor
US5965704A (en) * 1997-08-05 1999-10-12 Zymogenetics, Inc. Class two cytokine receptor-11
WO1999040195A1 (fr) * 1998-02-06 1999-08-12 Schering Corporation Proteines de recepteurs de mammiferes; reactifs et procedes apparentes
WO2000008152A1 (fr) * 1998-08-04 2000-02-17 Regeneron Pharmaceuticals, Inc. Nouveaux recepteurs de cytokine orphelins
EP1124851A1 (fr) * 1998-11-06 2001-08-22 Smithkline Beecham Corporation Hnovilr
WO2000069880A1 (fr) * 1999-05-18 2000-11-23 Millennium Pharmaceuticals, Inc. Molecules de type recepteurs d'il-9/il-2 et utilisation de ces dernieres
AU2253301A (en) * 1999-12-03 2001-06-12 Zymogenetics Inc. Human cytokine receptor
EP1242600B1 (fr) * 1999-12-23 2010-03-03 ZymoGenetics, Inc. La cytokine zcyto18

Also Published As

Publication number Publication date
JP2003523179A (ja) 2003-08-05
MXPA02005058A (es) 2002-11-07
EP1230368A2 (fr) 2002-08-14
AU1919201A (en) 2001-05-30
WO2001036467A3 (fr) 2002-05-10
WO2001036467A2 (fr) 2001-05-25

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead