CA2379863A1 - Polypeptides bloquant la kinase et leurs utilisations - Google Patents

Polypeptides bloquant la kinase et leurs utilisations Download PDF

Info

Publication number
CA2379863A1
CA2379863A1 CA002379863A CA2379863A CA2379863A1 CA 2379863 A1 CA2379863 A1 CA 2379863A1 CA 002379863 A CA002379863 A CA 002379863A CA 2379863 A CA2379863 A CA 2379863A CA 2379863 A1 CA2379863 A1 CA 2379863A1
Authority
CA
Canada
Prior art keywords
polypeptide
cpeb
seq
cell
blocking
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002379863A
Other languages
English (en)
Inventor
Joel D. Richter
Raul Mendez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Massachusetts UMass
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2379863A1 publication Critical patent/CA2379863A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

L'invention concerne des peptides (polypeptides bloquantes) qui empêchent l'activité de la kinase Eg2, et empêchent donc également l'activation de la protéine connue sous le nom de CPEB. L'invention concerne également des ADNs codant le polypeptide-CPEB, des vecteurs, des cellules contenant cet ADN et des anticorps spécifiques semblables à la CPEB.
CA002379863A 1999-07-21 2000-07-21 Polypeptides bloquant la kinase et leurs utilisations Abandoned CA2379863A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14490399P 1999-07-21 1999-07-21
US60/144,903 1999-07-21
PCT/US2000/020254 WO2001007466A1 (fr) 1999-07-21 2000-07-21 Polypeptides bloquant la kinase et leurs utilisations

Publications (1)

Publication Number Publication Date
CA2379863A1 true CA2379863A1 (fr) 2001-02-01

Family

ID=22510665

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002379863A Abandoned CA2379863A1 (fr) 1999-07-21 2000-07-21 Polypeptides bloquant la kinase et leurs utilisations

Country Status (5)

Country Link
EP (1) EP1203013A4 (fr)
JP (1) JP2003505064A (fr)
AU (1) AU6237700A (fr)
CA (1) CA2379863A1 (fr)
WO (1) WO2001007466A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1886422A (zh) * 2003-09-30 2006-12-27 恩卡姆医药公司 调节细胞存活、分化和/或突触可塑性的方法
DE602005023333D1 (de) 2004-10-15 2010-10-14 Takeda Pharmaceutical Kinaseinhibitoren
US8119655B2 (en) 2005-10-07 2012-02-21 Takeda Pharmaceutical Company Limited Kinase inhibitors
EA200970361A1 (ru) 2006-10-09 2010-02-26 Такеда Фармасьютикал Компани Лимитед Ингибиторы киназы

Also Published As

Publication number Publication date
EP1203013A1 (fr) 2002-05-08
AU6237700A (en) 2001-02-13
JP2003505064A (ja) 2003-02-12
EP1203013A4 (fr) 2004-10-13
WO2001007466A1 (fr) 2001-02-01

Similar Documents

Publication Publication Date Title
PACKHAM et al. Mammalian cells express two differently localized Bag-1 isoforms generated by alternative translation initiation
JPH09509304A (ja) Ｂｃｌ‐２会合タンパク質
WO1995013292A9 (fr) Proteines associees a la bcl-2
US20010018211A1 (en) Anti-proliferation domain of human Bcl-2 and DNA encoding the same
Drané et al. Identification of RB18A, a 205 kDa new p53 regulatory protein which shares antigenic and functional properties with p53
US20040167066A1 (en) Cleavage and polyadenylation complex of precursor mrna
AU688355B2 (en) Regulation of transcription factor, NF-IL6/LAP
JP4314386B2 (ja) Ｂｃｌ−２調節因子（ＢＭＦ）配列及びアポトーシスの調節におけるそれらの使用
US6025480A (en) Isolated nucleic acid molecules encoding P57KIP2
CA2379863A1 (fr) Polypeptides bloquant la kinase et leurs utilisations
JP2001510684A (ja) アッセイ、治療法及び治療手段
EP0981613A1 (fr) Parg, proteine d'activation de gtpase exer ant une interaction avec ptpl1
JPH09501567A (ja) 網膜芽細胞腫タンパク質に結合する新規タンパク質およびそれをコードするｄｎａ配列
US20060040372A1 (en) GANP protein
US6297019B1 (en) Recombinant polynucleotides encoding CYP7 promoter-binding factors
KR101083852B1 (ko) 유전자 전사 조절제 및 히스톤 탈아세틸화효소 저해 화합물의 스크리닝 방법
JP4522855B2 (ja) ＧＥＦ−Ｈ１ｂ：バイオマーカー，その複合体，アッセイおよび治療用途
WO1999047671A2 (fr) Sequences d'adn codant pour la semaphorine-h et diagnostic du cancer metastatique
EP1369478A1 (fr) Nouvelle proteine de classe a du type recepteur eboueur
JPH10313866A (ja) Ｄｏｃ２αとＭｕｎｃ１３との結合のアゴニストまたはアンタゴニストのスクリーニング方法
WO1997020573A1 (fr) Homologue de proteine 2 se liant au recepteur du facteur de croissance
JP2004535183A (ja) 遺伝子及びその使用
EP1357181A1 (fr) Nouveaux genes et proteines associes a la dermatite atopique
WO2001051509A2 (fr) Proteine 140 associee a shc (sap-140)
WO2002095025A1 (fr) Nouveau smg-1

Legal Events

Date Code Title Description
FZDE Discontinued