CA2373814A1 - Composes et methodes de regulation de l'apoptose, et methodes d'elaboration et de criblage de composes regulateurs de l'apoptose - Google Patents
Composes et methodes de regulation de l'apoptose, et methodes d'elaboration et de criblage de composes regulateurs de l'apoptose Download PDFInfo
- Publication number
- CA2373814A1 CA2373814A1 CA002373814A CA2373814A CA2373814A1 CA 2373814 A1 CA2373814 A1 CA 2373814A1 CA 002373814 A CA002373814 A CA 002373814A CA 2373814 A CA2373814 A CA 2373814A CA 2373814 A1 CA2373814 A1 CA 2373814A1
- Authority
- CA
- Canada
- Prior art keywords
- bad
- seq
- fragment
- amino acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4747—Apoptosis related proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13678399P | 1999-05-28 | 1999-05-28 | |
US60/136,783 | 1999-05-28 | ||
PCT/US2000/011864 WO2001010888A1 (fr) | 1999-05-28 | 2000-05-30 | Composes et methodes de regulation de l'apoptose, et methodes d'elaboration et de criblage de composes regulateurs de l'apoptose |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2373814A1 true CA2373814A1 (fr) | 2001-02-15 |
Family
ID=22474341
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002373814A Abandoned CA2373814A1 (fr) | 1999-05-28 | 2000-05-30 | Composes et methodes de regulation de l'apoptose, et methodes d'elaboration et de criblage de composes regulateurs de l'apoptose |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1181306A4 (fr) |
JP (1) | JP2003506071A (fr) |
AU (1) | AU765983B2 (fr) |
CA (1) | CA2373814A1 (fr) |
WO (1) | WO2001010888A1 (fr) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040082509A1 (en) | 1999-10-12 | 2004-04-29 | Christophe Bonny | Cell-permeable peptide inhibitors of the JNK signal transduction pathway |
US8183339B1 (en) | 1999-10-12 | 2012-05-22 | Xigen S.A. | Cell-permeable peptide inhibitors of the JNK signal transduction pathway |
EP1273654A1 (fr) * | 2001-07-05 | 2003-01-08 | Schering Aktiengesellschaft | BAD comme substrat pour PPC2 |
US6933127B2 (en) | 2001-07-05 | 2005-08-23 | Eucro European Contract Research Gmbh & Co. Kg | Substrate for PP2C |
EP1421952A4 (fr) * | 2001-08-22 | 2005-02-16 | Mitsuhiro Yokota | Inhibiteur d'apoptose de cellules myocardiques |
WO2003042239A1 (fr) * | 2001-11-12 | 2003-05-22 | Stichting Sanquin Bloedvoorziening | Peptides inhibant la signalisation des gtpases de type ras |
DK1343013T3 (da) * | 2002-03-07 | 2006-08-21 | Pasteur Institut | Fremgangsmåder til screening af forbindelser der modulerer apoptose, forbindelser der er identificeret ved fremgangsmåderne, og anvendelse af forbindelserne som terapeutiske midler |
EP1499343A4 (fr) * | 2002-03-28 | 2005-12-28 | Medvet Science Pty Ltd | Methode de modulation d'activite cellulaire |
JP2004018524A (ja) * | 2002-06-13 | 2004-01-22 | Eucro European Contract Research Gmbh & Co Kg | 動脈硬化症を処置するための方法 |
EP1661912A1 (fr) * | 2004-11-29 | 2006-05-31 | Xigen S.A. | Protéine de fusion comprenant un domaine BH3 d'une protéine BH3-only |
WO2007031098A1 (fr) | 2005-09-12 | 2007-03-22 | Xigen S.A. | Inhibiteurs peptidiques permeables aux cellules de la voie de transduction de signal jnk |
US8080517B2 (en) | 2005-09-12 | 2011-12-20 | Xigen Sa | Cell-permeable peptide inhibitors of the JNK signal transduction pathway |
WO2007035494A2 (fr) * | 2005-09-16 | 2007-03-29 | The Regents Of The University Of California | Induction de l'expression de puma permettant de reduire l'inflammation articulaire dans le traitement de l'arthrite |
CA2681808A1 (fr) * | 2007-03-20 | 2008-09-25 | The Walter And Eliza Hall Institute Of Medical Research | Procede de criblage |
WO2009143864A1 (fr) | 2008-05-30 | 2009-12-03 | Xigen S.A. | Utilisation d'inhibiteurs peptidiques perméables aux cellules de la voie de transduction du signal jnk pour le traitement de maladies digestives inflammatoires chroniques ou non chroniques |
WO2009143865A1 (fr) | 2008-05-30 | 2009-12-03 | Xigen S.A. | Utilisation d'inhibiteurs peptidiques des voies de traduction du signal jnk perméables aux cellules pour le traitement de diverses maladies |
WO2010072228A1 (fr) | 2008-12-22 | 2010-07-01 | Xigen S.A. | Nouvelles constructions transporteuses et molécules conjuguées cargo/transporteuses |
WO2011160653A1 (fr) | 2010-06-21 | 2011-12-29 | Xigen S.A. | Nouvelles molécules inhibant jnk |
JP5857056B2 (ja) | 2010-10-14 | 2016-02-10 | ザイジェン インフラメーション エルティーディー | 慢性又は非慢性の炎症性眼疾患を治療するためのjnkシグナル伝達経路の細胞透過性ペプチド阻害剤の使用 |
WO2013091670A1 (fr) | 2011-12-21 | 2013-06-27 | Xigen S.A. | Nouvelles molécules inhibitrices de jnk pour le traitement de diverses maladies |
WO2015197097A1 (fr) | 2014-06-26 | 2015-12-30 | Xigen Inflammation Ltd. | Nouvelle utilisation pour des molécules inhibitrices de la jnk, pour le traitement de diverses maladies |
KR20160023669A (ko) | 2013-06-26 | 2016-03-03 | 자이겐 인플라메이션 리미티드 | 다양한 질병의 치료를 위한 jnk 신호 전달 경로의 세포 투과성 펩타이드 억제자의 새로운 용도 |
WO2014206427A1 (fr) | 2013-06-26 | 2014-12-31 | Xigen Inflammation Ltd. | Nouvelle utilisation d'inhibiteurs de peptides à perméabilité cellulaire dans la voie de transduction du signal jnk pour le traitement de diverses maladies |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5965703A (en) * | 1996-09-20 | 1999-10-12 | Idun Pharmaceuticals | Human bad polypeptides, encoding nucleic acids and methods of use |
-
2000
- 2000-05-30 JP JP2001515696A patent/JP2003506071A/ja not_active Withdrawn
- 2000-05-30 AU AU51253/00A patent/AU765983B2/en not_active Ceased
- 2000-05-30 CA CA002373814A patent/CA2373814A1/fr not_active Abandoned
- 2000-05-30 WO PCT/US2000/011864 patent/WO2001010888A1/fr active IP Right Grant
- 2000-05-30 EP EP00935853A patent/EP1181306A4/fr not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
EP1181306A1 (fr) | 2002-02-27 |
AU5125300A (en) | 2001-03-05 |
EP1181306A4 (fr) | 2003-06-18 |
WO2001010888A1 (fr) | 2001-02-15 |
AU765983B2 (en) | 2003-10-09 |
JP2003506071A (ja) | 2003-02-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Discontinued |