CA2335346A1 - Proteines sara - Google Patents

Proteines sara Download PDF

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Publication number
CA2335346A1
CA2335346A1 CA002335346A CA2335346A CA2335346A1 CA 2335346 A1 CA2335346 A1 CA 2335346A1 CA 002335346 A CA002335346 A CA 002335346A CA 2335346 A CA2335346 A CA 2335346A CA 2335346 A1 CA2335346 A1 CA 2335346A1
Authority
CA
Canada
Prior art keywords
sara
sequence
protein
smad2
hsarai
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002335346A
Other languages
English (en)
Inventor
Jeffrey L. Wrana
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HSC Research and Development LP
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA 2237701 external-priority patent/CA2237701A1/fr
Priority claimed from CA002253647A external-priority patent/CA2253647A1/fr
Application filed by Individual filed Critical Individual
Priority to CA002335346A priority Critical patent/CA2335346A1/fr
Publication of CA2335346A1 publication Critical patent/CA2335346A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/463Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from amphibians
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/07Animals genetically altered by homologous recombination
    • A01K2217/075Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out

Abstract

La présente invention concerne une famille de protéines récemment identifiée, les protéines SARA. Ces protéines, qui se lient aux protéines Smad à régulation par les récepteurs, modulent la transduction de signal par le TGF.beta., et se lient également à l'activine et à la protéine de morphogenèse des os.
CA002335346A 1998-07-20 1999-07-20 Proteines sara Abandoned CA2335346A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002335346A CA2335346A1 (fr) 1998-07-20 1999-07-20 Proteines sara

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
CA 2237701 CA2237701A1 (fr) 1998-07-20 1998-07-20 Proteines liantes smad
CA2,237,701 1998-07-20
CA2,253,647 1998-12-10
CA002253647A CA2253647A1 (fr) 1998-07-20 1998-12-10 Proteines liantes smad
CA002335346A CA2335346A1 (fr) 1998-07-20 1999-07-20 Proteines sara
PCT/CA1999/000656 WO2000005360A1 (fr) 1998-07-20 1999-07-20 Proteines sara

Publications (1)

Publication Number Publication Date
CA2335346A1 true CA2335346A1 (fr) 2000-02-03

Family

ID=27170687

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002335346A Abandoned CA2335346A1 (fr) 1998-07-20 1999-07-20 Proteines sara

Country Status (1)

Country Link
CA (1) CA2335346A1 (fr)

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Legal Events

Date Code Title Description
FZDE Discontinued