CA2332825A1 - Peripheral benzodiazepine receptor ligands - Google Patents

Peripheral benzodiazepine receptor ligands Download PDF

Info

Publication number
CA2332825A1
CA2332825A1 CA002332825A CA2332825A CA2332825A1 CA 2332825 A1 CA2332825 A1 CA 2332825A1 CA 002332825 A CA002332825 A CA 002332825A CA 2332825 A CA2332825 A CA 2332825A CA 2332825 A1 CA2332825 A1 CA 2332825A1
Authority
CA
Canada
Prior art keywords
compound
compounds
inflammatory condition
mammal
peripheral benzodiazepine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002332825A
Other languages
English (en)
French (fr)
Inventor
Edith G. Mcgeer
J. Douglas Waterfield
Andis Klegeris
Patrick L. Mcgeer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
University of British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of British Columbia filed Critical University of British Columbia
Publication of CA2332825A1 publication Critical patent/CA2332825A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002332825A 1998-05-22 1998-05-22 Peripheral benzodiazepine receptor ligands Abandoned CA2332825A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CA1998/000502 WO1999061024A1 (en) 1998-05-22 1998-05-22 Peripheral benzodiazepine receptor ligands

Publications (1)

Publication Number Publication Date
CA2332825A1 true CA2332825A1 (en) 1999-12-02

Family

ID=4173300

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002332825A Abandoned CA2332825A1 (en) 1998-05-22 1998-05-22 Peripheral benzodiazepine receptor ligands

Country Status (5)

Country Link
EP (1) EP1077702A1 (de)
JP (1) JP2002516279A (de)
AU (1) AU7516898A (de)
CA (1) CA2332825A1 (de)
WO (1) WO1999061024A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030162759A1 (en) * 2000-07-27 2003-08-28 Ricardo Rocha Aldosterone blocker therapy to prevent or treat inflammation-related disorders
EP1438973A4 (de) * 2001-10-05 2005-07-13 Ono Pharmaceutical Co Mittel zur behandlung von stressbedingten erkrankungen mit mitochondrien-benzodiazepin-rezeptorantagonisten
JP4362457B2 (ja) 2005-04-26 2009-11-11 独立行政法人科学技術振興機構 神経因性疼痛治療剤

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5091381A (en) * 1991-04-12 1992-02-25 Biomeasure, Inc. 2H-1,3,4-benzotriazepin-2-ones

Also Published As

Publication number Publication date
JP2002516279A (ja) 2002-06-04
WO1999061024A1 (en) 1999-12-02
EP1077702A1 (de) 2001-02-28
AU7516898A (en) 1999-12-13

Similar Documents

Publication Publication Date Title
US5776946A (en) Peripheral benzodiazepine receptor ligands as antiinflammatory agents
Wrathall et al. Evidence that local non-NMDA receptors contribute to functional deficits in contusive spinal cord injury
CZ284363B6 (cs) Použití protikřečových činidel k přípravě léčiv určených k léčení Parkinsonovy choroby a Parkinsonových syndromů
JP2003507421A (ja) トラマドール物質及び抗痙攣薬を含んで成る組成物
AU2002218467A2 (en) Anti-proliferative drugs
KR20010021865A (ko) 카파 작용제 항소양성 약학적 조성물 및 이를 이용한소양증의 치료 방법
AU707077B2 (en) Use of 1,2,4-triazole derivatives for the manufacture of a medicament for the treatment of cancers
AU2004233587A1 (en) Use of a topical medicament comprising Riluzole
JP5409602B2 (ja) 慢性疼痛の治療におけるジミラセタムの使用
ATE254463T1 (de) Verwendung von valaciclovir zur herstellung eines arzneimittels zur behandlung von genitalherpes durch einmal tägliche verabreichung
KR101327150B1 (ko) 척수 손상 치료를 위한 ｎ-(2-아릴-프로피오닐)-술폰아마이드의 용도
JPH07505646A (ja) 神経伝達速度の減損を伴う障害，特に糖尿病性ニューロパシーに対するアンギオテンシンｉｉアンタゴニスト
CA2332825A1 (en) Peripheral benzodiazepine receptor ligands
JP2706371B2 (ja) 癌治療用補助剤及びそれを用いたキット
JP2001517202A (ja) 痛み処置方法
Wang et al. Alkaloids of Chinese aconitum plants
Lenfant et al. In vivo immunomodulating activity of PK 1195, a structurally unrelated ligand for “peripheral” benzodiazepine binding sites—I. Potentiation in mice of the humoral response to sheep red blood cells
EP0099186B1 (de) Pharmazeutische Zusammensetzungen
NO974486L (no) Lavdoserte "Ridogrel"-formuleringer samt anvendelse derav ved behandling av tarmbetennelse
US6534500B2 (en) Use of cyamemazine in the treatment of abrupt benzodiazephine withdrawal
ITMI951417A1 (it) Composizioni farmaceutiche e procedimento per la loro preparazione
NL8002041A (nl) Werkwijze voor het bereiden van een analgetisch en myotonolytisch geneesmiddel.
CN1106194C (zh) 组合物
Takahashi et al. Different effects of L-type and T-type calcium channel blockers on the hypnotic potency of triazolam and zolpidem in rats
JP3015129B2 (ja) ベンゾジアゼピン化合物を用いる新規治療法

Legal Events

Date Code Title Description
FZDE Discontinued