CA2329076A1 - Homologues de l'hydrolase humaine, asparagine amidohydrolase n-terminale, glycosylhydrolase, glucohydrolase, biotinidase, et n-acetylglucosamine 6-p-deacetylase - Google Patents

Homologues de l'hydrolase humaine, asparagine amidohydrolase n-terminale, glycosylhydrolase, glucohydrolase, biotinidase, et n-acetylglucosamine 6-p-deacetylase Download PDF

Info

Publication number
CA2329076A1
CA2329076A1 CA002329076A CA2329076A CA2329076A1 CA 2329076 A1 CA2329076 A1 CA 2329076A1 CA 002329076 A CA002329076 A CA 002329076A CA 2329076 A CA2329076 A CA 2329076A CA 2329076 A1 CA2329076 A1 CA 2329076A1
Authority
CA
Canada
Prior art keywords
hhh
leu
polynucleotide
gly
ala
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002329076A
Other languages
English (en)
Inventor
Olga Bandman
Jennifer L. Hillman
Henry Yue
Preeti Lal
Neil C. Corley
Karl J. Guegler
Chandra Patterson
Mariah R. Baughn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2329076A1 publication Critical patent/CA2329076A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C12N9/82—Asparaginase (3.5.1.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

L'invention porte sur des homologues de l'hydrolase humaine (HHH) et des polynucléotides identifiant la HHH et codant pour elle. L'invention porte également sur des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes associés ainsi que sur des méthodes de diagnostic, traitement et prévention de troubles associés à l'expression du HHH.
CA002329076A 1998-05-29 1999-05-28 Homologues de l'hydrolase humaine, asparagine amidohydrolase n-terminale, glycosylhydrolase, glucohydrolase, biotinidase, et n-acetylglucosamine 6-p-deacetylase Abandoned CA2329076A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8723698P 1998-05-29 1998-05-29
US60/087,236 1998-05-29
PCT/US1999/012021 WO1999061626A2 (fr) 1998-05-29 1999-05-28 Homologues de l'hydrolase humaine, asparagine amidohydrolase n-terminale, glycosylhydrolase, glucohydrolase, biotinidase, et n-acetylglucosamine 6-p-deacetylase

Publications (1)

Publication Number Publication Date
CA2329076A1 true CA2329076A1 (fr) 1999-12-02

Family

ID=22203944

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002329076A Abandoned CA2329076A1 (fr) 1998-05-29 1999-05-28 Homologues de l'hydrolase humaine, asparagine amidohydrolase n-terminale, glycosylhydrolase, glucohydrolase, biotinidase, et n-acetylglucosamine 6-p-deacetylase

Country Status (5)

Country Link
EP (1) EP1080203A2 (fr)
JP (1) JP2003500002A (fr)
AU (1) AU4322299A (fr)
CA (1) CA2329076A1 (fr)
WO (1) WO1999061626A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL178921A0 (en) 1998-12-24 2007-03-08 Yeda Res & Dev Caspase-8 interacting proteins
CN1301854A (zh) * 1999-12-29 2001-07-04 复旦大学 一种新的多肽——糖基水解酶12和编码这种多肽的多核苷酸
WO2003054153A2 (fr) * 2001-12-12 2003-07-03 University Of Cincinnati Polypeptides de l'apyrase et acides nucleiques codant pour ces polypeptides
AU2003231245A1 (en) * 2002-04-30 2003-11-17 Incyte Corporation Molecules for disease detection and treatment

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6537547B1 (en) * 1996-06-07 2003-03-25 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Polypeptides having L-asparaginase activity
US5958750A (en) * 1996-07-03 1999-09-28 Inctye Pharmaceuticals, Inc. Human hyaluronidase

Also Published As

Publication number Publication date
JP2003500002A (ja) 2003-01-07
EP1080203A2 (fr) 2001-03-07
WO1999061626A2 (fr) 1999-12-02
WO1999061626A3 (fr) 2000-04-06
AU4322299A (en) 1999-12-13

Similar Documents

Publication Publication Date Title
US20080182977A1 (en) Molecules associated with cell proliferation
WO2000006728A2 (fr) Effecteurs de phosphorylation
WO2000022143A2 (fr) Homologues de proteines kinases
CA2327354A1 (fr) Proteines associees a l'apoptose humaine
US5888793A (en) Human lysophosphatidic acid acyltransferase
US6171843B1 (en) Human peptidyl-prolyl isomerases
US6391580B1 (en) Ras proteins
CA2313448A1 (fr) Proteine de conjugaison du type ubiquitine
US20020173022A1 (en) Human protein phosphatase
CA2312991A1 (fr) Serine protease associee a la prostate
US5962302A (en) Human N-acetylneuraminate lyase
US6943244B2 (en) Human g-type lysozyme, the encoding sequence, preparing method and the uses thereof
WO2000004135A2 (fr) Molecules apparentees a l'alcool-deshydrogenase chaine courte de type humain, scrm-1 et scrm-2
CA2303227A1 (fr) Phosphatase prl-1 humaine
EP1064370A2 (fr) Molecules apparentees a la proteine-phosphatase
CA2329076A1 (fr) Homologues de l'hydrolase humaine, asparagine amidohydrolase n-terminale, glycosylhydrolase, glucohydrolase, biotinidase, et n-acetylglucosamine 6-p-deacetylase
US20020102654A1 (en) Thioredoxin proteins
US6180342B1 (en) Vacuolar proton ATPase subunits
US6432687B1 (en) Delayed rectifier potassium channel subunit
US20040086923A1 (en) Carbamoyl phosphate synthase homolog
US6558914B1 (en) Human lysophosphatidic acid acyltransferase
CA2329688A1 (fr) Proteines de regulation du cycle cellulaire
WO1999050396A1 (fr) Proteine kinase de type nek-1
CA2328510A1 (fr) Methylases d'acides nucleiques humains
CA2317920A1 (fr) Proteine humaine de calcineurine de type b

Legal Events

Date Code Title Description
FZDE Dead