CA2324350A1 - Cellules souches d'origine cardiaque - Google Patents
Cellules souches d'origine cardiaque Download PDFInfo
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- CA2324350A1 CA2324350A1 CA002324350A CA2324350A CA2324350A1 CA 2324350 A1 CA2324350 A1 CA 2324350A1 CA 002324350 A CA002324350 A CA 002324350A CA 2324350 A CA2324350 A CA 2324350A CA 2324350 A1 CA2324350 A1 CA 2324350A1
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- cells
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- cardiac
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- derived stem
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0668—Mesenchymal stem cells from other natural sources
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0657—Cardiomyocytes; Heart cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Biomedical Technology (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- General Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Developmental Biology & Embryology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7913298P | 1998-03-23 | 1998-03-23 | |
| US60/079,132 | 1998-03-23 | ||
| PCT/US1999/006356 WO1999049015A2 (fr) | 1998-03-23 | 1999-03-23 | Cellules souches d'origine cardiaque |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2324350A1 true CA2324350A1 (fr) | 1999-09-30 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002324350A Abandoned CA2324350A1 (fr) | 1998-03-23 | 1999-03-23 | Cellules souches d'origine cardiaque |
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|---|---|
| EP (1) | EP1064356A2 (fr) |
| JP (1) | JP2002507407A (fr) |
| AU (1) | AU3112499A (fr) |
| CA (1) | CA2324350A1 (fr) |
| WO (1) | WO1999049015A2 (fr) |
Families Citing this family (52)
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| US7514074B2 (en) | 1997-07-14 | 2009-04-07 | Osiris Therapeutics, Inc. | Cardiac muscle regeneration using mesenchymal stem cells |
| EP1894997A1 (fr) * | 1998-07-31 | 2008-03-05 | Genzyme Corporation | Amélioration de la fonction cardiaque par transplantation de cellules souches mésenchymateuses |
| BR9912662A (pt) * | 1998-07-31 | 2001-06-05 | Genzyme Corp | Melhoria de função cardìaca por transplante de célula de ramo mesenquimal |
| FR2810045B1 (fr) * | 2000-06-07 | 2004-09-03 | Assist Publ Hopitaux De Paris | Procede d'obtention de population cellulaires caracterisees d'origine musculaire et utilisations |
| US7862810B2 (en) | 2000-07-31 | 2011-01-04 | New York Medical College | Methods and compositions for the repair and/or regeneration of damaged myocardium |
| US20020061587A1 (en) | 2000-07-31 | 2002-05-23 | Piero Anversa | Methods and compositions for the repair and/or regeneration of damaged myocardium |
| EP2338983B1 (fr) * | 2001-02-14 | 2015-10-07 | Anthrogenesis Corporation | Renovation et repeuplement de tissus decellularises er d'organes preleves sur des cadavres par des cellules souches. |
| JP2004531256A (ja) | 2001-04-24 | 2004-10-14 | バクシュ，ドロレス | 前駆細胞集団、その増殖、及びそれからの非造血細胞種及び組織の成長 |
| EP1391505B1 (fr) * | 2001-04-24 | 2009-01-28 | Ajinomoto Co., Inc. | Cellules souches et procede d'extraction de ces cellules |
| JP2003018984A (ja) * | 2001-07-06 | 2003-01-21 | Mitsubishi Chemicals Corp | 多分化能を有する細胞の製造法 |
| AU2002313670C1 (en) | 2001-07-12 | 2009-08-06 | Asterias Biotherapeutics, Inc. | Cells of the cardiomyocyte lineage produced from human pluripotent stem cells |
| US7732199B2 (en) | 2001-07-12 | 2010-06-08 | Geron Corporation | Process for making transplantable cardiomyocytes from human embryonic stem cells |
| WO2003024462A1 (fr) | 2001-09-19 | 2003-03-27 | Henry Ford Health System | Transplantation cardiaque de cellules souches pour le traitement de l'insuffisance cardiaque |
| US20040247575A1 (en) * | 2003-06-03 | 2004-12-09 | Caplice Noel M. | Smooth muscle progenitor cells |
| ITRM20030376A1 (it) | 2003-07-31 | 2005-02-01 | Univ Roma | Procedimento per l'isolamento e l'espansione di cellule staminali cardiache da biopsia. |
| US7452718B2 (en) | 2004-03-26 | 2008-11-18 | Geron Corporation | Direct differentiation method for making cardiomyocytes from human embryonic stem cells |
| JP5202953B2 (ja) * | 2004-11-08 | 2013-06-05 | ザ ジョンズ ホプキンス ユニバーシティー | 心臓幹細胞 |
| US11660317B2 (en) | 2004-11-08 | 2023-05-30 | The Johns Hopkins University | Compositions comprising cardiosphere-derived cells for use in cell therapy |
| CA2590338A1 (fr) * | 2005-01-25 | 2006-08-03 | Five Prime Therapeutics, Inc. | Compositions et methodes de traitement de troubles cardiaques |
| CA2611809C (fr) | 2005-06-22 | 2018-06-19 | Geron Corporation | Differenciation de cellules souches pluripotentes en cellules a lignage cardiomyocyte |
| EP1790350A1 (fr) * | 2005-11-24 | 2007-05-30 | Interstitial Therapeutics | Utilisation d'une composition contenant de la kératinocyte pour le traitement de la restenose |
| JP2009531021A (ja) | 2006-02-16 | 2009-09-03 | フォンダッチォーネ・セントロ・サン・ラファエル・デル・モンテ・タボール | 骨格筋周囲血管芽細胞および心筋中胚葉性血管芽細胞、それらの単離および使用方法 |
| AU2007325698B2 (en) * | 2006-11-28 | 2014-03-20 | University Of Pittsburgh | Muscle derived cells for the treatment of cardiac pathologies and methods of making and using the same |
| WO2008081457A2 (fr) * | 2007-01-04 | 2008-07-10 | Ramot At Tel Aviv University Ltd. | Méthodes d'isolation de cellules souches cardiaques, constitution de banques de cellules souches et utilisations de celles-ci |
| DE102007008650B4 (de) | 2007-02-20 | 2012-06-06 | Charité - Universitätsmedizin Berlin | Zellen zur Therapie des Herzens |
| EP2227238A2 (fr) | 2007-11-30 | 2010-09-15 | New York Medical College | Compositions comprenant des cellules progénitrices vasculaires et myocytaires et procédés permettant de les utiliser |
| US8512696B2 (en) | 2007-11-30 | 2013-08-20 | Autologous, Llc | Methods of isolating non-senescent cardiac stem cells and uses thereof |
| US8124071B2 (en) | 2007-11-30 | 2012-02-28 | New York Medical College | Methods of reducing transplant rejection and cardiac allograft vasculopathy by implanting autologous stem cells |
| US8241907B2 (en) | 2008-01-30 | 2012-08-14 | Geron Corporation | Synthetic surfaces for culturing stem cell derived cardiomyocytes |
| KR101834800B1 (ko) * | 2009-07-09 | 2018-03-06 | 얀센 바이오테크 인코포레이티드 | 심장 조직-유래 세포 |
| US9845457B2 (en) | 2010-04-30 | 2017-12-19 | Cedars-Sinai Medical Center | Maintenance of genomic stability in cultured stem cells |
| US9249392B2 (en) | 2010-04-30 | 2016-02-02 | Cedars-Sinai Medical Center | Methods and compositions for maintaining genomic stability in cultured stem cells |
| WO2012048298A2 (fr) | 2010-10-08 | 2012-04-12 | Caridianbct, Inc. | Procédés et systèmes de culture et de récolte de cellules dans un système de bioréacteur à fibres creuses avec conditions de régulation |
| AU2012204501B2 (en) | 2011-01-03 | 2016-05-19 | Avm Biotechnology, Llc | Personalized production of biologics and method for reprogramming somatic cells |
| JP2015521054A (ja) | 2012-06-05 | 2015-07-27 | カプリコール，インコーポレイテッド | 心臓組織から心臓幹細胞を作製するための最適化方法および心臓治療におけるそれらの使用 |
| WO2014028493A2 (fr) | 2012-08-13 | 2014-02-20 | Cedars-Sinai Medical Center | Exosomes et acides micro-ribonucléiques pour la régénération de tissus |
| US9617506B2 (en) | 2013-11-16 | 2017-04-11 | Terumo Bct, Inc. | Expanding cells in a bioreactor |
| US11008547B2 (en) | 2014-03-25 | 2021-05-18 | Terumo Bct, Inc. | Passive replacement of media |
| JP6830059B2 (ja) | 2014-09-26 | 2021-02-17 | テルモ ビーシーティー、インコーポレーテッド | スケジュール化された細胞フィーディング |
| WO2016054591A1 (fr) | 2014-10-03 | 2016-04-07 | Cedars-Sinai Medical Center | Cellules dérivées de la cardiosphère et exosomes sécrétés par ces cellules dans le traitement d'une dystrophie musculaire |
| WO2017004592A1 (fr) | 2015-07-02 | 2017-01-05 | Terumo Bct, Inc. | Croissance cellulaire à l'aide de stimuli mécaniques |
| EP3402543B1 (fr) | 2016-01-11 | 2021-09-08 | Cedars-Sinai Medical Center | Cellules dérivées de cardiosphères et exosomes sécrétés par ces cellules dans le traitement d'une insuffisance cardiaque à fraction d'éjection préservée |
| US11965175B2 (en) | 2016-05-25 | 2024-04-23 | Terumo Bct, Inc. | Cell expansion |
| US11351200B2 (en) | 2016-06-03 | 2022-06-07 | Cedars-Sinai Medical Center | CDC-derived exosomes for treatment of ventricular tachyarrythmias |
| US11104874B2 (en) | 2016-06-07 | 2021-08-31 | Terumo Bct, Inc. | Coating a bioreactor |
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| WO2018026766A1 (fr) | 2016-08-01 | 2018-02-08 | The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Compositions et procédés pour traiter une affection cardiaque |
| WO2018057542A1 (fr) | 2016-09-20 | 2018-03-29 | Cedars-Sinai Medical Center | Cellules dérivées de cardiosphères et leurs vésicules extracellulaires pour retarder ou inverser le vieillissement et des troubles liés à l'âge |
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| EP3612191A4 (fr) | 2017-04-19 | 2020-12-30 | Cedars-Sinai Medical Center | Méthodes et compositions pour traiter une dystrophie musculaire squelettique |
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Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH10505498A (ja) * | 1994-09-09 | 1998-06-02 | ザイモジェネティクス，インコーポレイティド | 不死化細胞の調製 |
| DE4441327C1 (de) * | 1994-11-22 | 1995-11-09 | Inst Pflanzengenetik & Kultur | Embryonale Herzmuskelzellen, ihre Herstellung und ihre Verwendung |
| US5919449A (en) * | 1995-05-30 | 1999-07-06 | Diacrin, Inc. | Porcine cardiomyocytes and their use in treatment of insufficient cardiac function |
-
1999
- 1999-03-23 WO PCT/US1999/006356 patent/WO1999049015A2/fr not_active Application Discontinuation
- 1999-03-23 AU AU31124/99A patent/AU3112499A/en not_active Abandoned
- 1999-03-23 JP JP2000537976A patent/JP2002507407A/ja active Pending
- 1999-03-23 EP EP99912853A patent/EP1064356A2/fr not_active Withdrawn
- 1999-03-23 CA CA002324350A patent/CA2324350A1/fr not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999049015A3 (fr) | 1999-12-16 |
| AU3112499A (en) | 1999-10-18 |
| JP2002507407A (ja) | 2002-03-12 |
| EP1064356A2 (fr) | 2001-01-03 |
| WO1999049015A2 (fr) | 1999-09-30 |
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