CA2282722A1 - Method of cloning animals - Google Patents

Method of cloning animals Download PDF

Info

Publication number
CA2282722A1
CA2282722A1 CA002282722A CA2282722A CA2282722A1 CA 2282722 A1 CA2282722 A1 CA 2282722A1 CA 002282722 A CA002282722 A CA 002282722A CA 2282722 A CA2282722 A CA 2282722A CA 2282722 A1 CA2282722 A1 CA 2282722A1
Authority
CA
Canada
Prior art keywords
cells
cell
embryo
totipotent
mammalian
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002282722A
Other languages
English (en)
French (fr)
Inventor
Nikolai S. Strelchenko
Jeffery M. Betthauser
Gail L. Jurgella
Marvin M. Pace
Michael D. Bishop
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Infigen Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2282722A1 publication Critical patent/CA2282722A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • C12N15/877—Techniques for producing new mammalian cloned embryos
    • C12N15/8771—Bovine embryos
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0608—Germ cells
    • C12N5/0611—Primordial germ cells, e.g. embryonic germ cells [EG]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/04—Immortalised cells

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Fertilizers (AREA)
  • Steroid Compounds (AREA)
CA002282722A 1997-03-06 1998-03-05 Method of cloning animals Abandoned CA2282722A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US81285197A 1997-03-06 1997-03-06
US81203197A 1997-03-06 1997-03-06
US08/812,851 1997-03-06
US08/812,031 1997-03-06
US7301998P 1998-01-29 1998-01-29
US60/073,019 1998-01-29
PCT/US1998/004345 WO1998039416A1 (en) 1997-03-06 1998-03-05 Method of cloning animals

Publications (1)

Publication Number Publication Date
CA2282722A1 true CA2282722A1 (en) 1998-09-11

Family

ID=27372211

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002282722A Abandoned CA2282722A1 (en) 1997-03-06 1998-03-05 Method of cloning animals

Country Status (7)

Country Link
EP (1) EP0973871A1 (ja)
JP (1) JP2002512510A (ja)
AU (1) AU745334B2 (ja)
BR (1) BR9808192A (ja)
CA (1) CA2282722A1 (ja)
NZ (1) NZ337495A (ja)
WO (1) WO1998039416A1 (ja)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6331659B1 (en) * 1998-01-21 2001-12-18 University Of Hawaii Cumulus cells as nuclear donors
CA2323094A1 (en) * 1998-03-02 1999-09-10 University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, As Represented By Its Amherst Campus Embryonic or stem-like cell lines produced by cross-species nuclear transplantation
US6700037B2 (en) * 1998-11-24 2004-03-02 Infigen, Inc. Method of cloning porcine animals
US6258998B1 (en) * 1998-11-24 2001-07-10 Infigen, Inc. Method of cloning porcine animals
EP1141265B1 (en) * 1999-01-13 2008-09-03 Revivicor, Inc. Double nuclear transfer method and results thereof
CA2361943C (en) * 1999-03-04 2011-05-17 Ppl Therapeutics (Scotland) Limited Genetic modification of somatic cells and uses thereof
EP1191840B1 (en) * 1999-06-04 2007-01-17 Istituto Zootecnico E Caseario per La Sardegna Process for reconstructing a non-human animal embryo by nuclear transfer and preparing the animal therefrom.
JP2003503045A (ja) * 1999-06-30 2003-01-28 ワン，ウー−サク 異種間核移植技術を用いたクローントラの生産方法
WO2001000795A1 (en) * 1999-06-30 2001-01-04 Hwang, Woo-Suk A method for producing cloned cows
BR0013844A (pt) * 1999-09-07 2002-05-14 Advanced Cell Tech Inc Restauração de telÈmero e extensão de perìodo de vida da célula em animais clonados de células somáticas senescentes
US6906238B2 (en) 2000-03-15 2005-06-14 University Of Georgia Research Foundation, Inc. Effective nuclear reprogramming in mammals using CDK2 inhibitors
WO2002009510A2 (en) * 2000-08-01 2002-02-07 Xy Genetics, Llc Methods of selecting and cloning animals
CA2430738A1 (en) * 2000-12-05 2002-06-13 Universite De Montreal Method of cloning animals
EP1434988A4 (en) 2001-02-23 2005-12-14 Elan Pharm Inc TRANSGENIC ANIMALS KNOCKOUT WITH GENE BACE-1 INACTIVE
EP1370132A2 (en) 2001-03-21 2003-12-17 Geron Corporation Use of telomerase reverse transcriptase to create homozygous knockout animals
BR0309610A (pt) * 2002-04-24 2005-06-28 Univ Georgia Res Found Produção de filhotes clonados à partir de carcaças resfriadas
DK1523496T3 (da) 2002-07-18 2011-10-17 Merus B V Rekombinant fremstilling af blanding af antistoffer
USRE47770E1 (en) 2002-07-18 2019-12-17 Merus N.V. Recombinant production of mixtures of antibodies
AU2003290689A1 (en) 2002-11-08 2004-06-03 Kyowa Hakko Kirin Co., Ltd. Transgenic ungulates having reduced prion protein activity and uses thereof
US20100069614A1 (en) 2008-06-27 2010-03-18 Merus B.V. Antibody producing non-human mammals
ES2408582T3 (es) 2003-05-30 2013-06-21 Merus B.V. Biblioteca de Fab para la preparación de una mezcla de anticuerpos
WO2005068622A2 (en) 2004-01-20 2005-07-28 Merus B.V. Mixtures of binding proteins
WO2005104835A2 (en) 2004-04-22 2005-11-10 Kirin Beer Kabushiki Kaisha Transgenic animals and uses thereof
JP2006081542A (ja) * 2004-08-18 2006-03-30 Institute Of Physical & Chemical Research クローン哺乳動物の作成方法
AU2008218998A1 (en) 2007-02-23 2008-08-28 Advanced Cell Technology, Inc. Highly efficient methods for reprogramming differentiated cells and for generating animals and embryonic stem cells from reprogrammed cells
EP2987498B1 (en) 2008-05-02 2017-07-05 Laboratoire Français du Fractionnement et des Biotechnologies Treatment of bleeding with low half-life fibrinogen
US9796788B2 (en) 2010-02-08 2017-10-24 Regeneron Pharmaceuticals, Inc. Mice expressing a limited immunoglobulin light chain repertoire
US20130045492A1 (en) 2010-02-08 2013-02-21 Regeneron Pharmaceuticals, Inc. Methods For Making Fully Human Bispecific Antibodies Using A Common Light Chain
RU2724663C2 (ru) 2010-02-08 2020-06-25 Ридженерон Фармасьютикалз, Инк. Мышь с общей легкой цепью
EP2603581B1 (en) 2010-08-11 2019-07-17 INSERM (Institut National de la Santé et de la Recherche Médicale) Cocultures of cumulus cells and embryos during in vitro fertilization procedures
WO2012122512A1 (en) 2011-03-10 2012-09-13 Hco Antibody, Inc. Recombinant production of mixtures of single chain antibodies
SI2739740T1 (sl) 2011-08-05 2019-12-31 Regeneron Pharmaceuticals, Inc. Humanizirane univerzalne lahkoverižne miši
EP3594232A1 (en) 2012-04-20 2020-01-15 Merus N.V. Methods and means for the production of ig-like molecules
WO2015143414A2 (en) 2014-03-21 2015-09-24 Regeneron Pharmaceuticals, Inc. Non-human animals that make single domain binding proteins
AU2016232715A1 (en) 2015-03-19 2017-09-28 Regeneron Pharmaceuticals, Inc. Non-human animals that select for light chain variable regions that bind antigen

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU623922B2 (en) * 1988-08-04 1992-05-28 Amrad Operations Pty. Limited In vitro propagation of embryonic stem cells
JP2988753B2 (ja) * 1990-08-29 1999-12-13 科学技術振興事業団 不死化細胞株の樹立方法とその細胞株
AU6136394A (en) * 1992-10-06 1994-04-26 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Long-term proliferation of primordial germ cells
US5453357A (en) * 1992-10-08 1995-09-26 Vanderbilt University Pluripotential embryonic stem cells and methods of making same
WO1995016770A1 (en) * 1993-12-17 1995-06-22 Abs Global, Inc. Ungulate preblastocyst derived embryonic stem cells and use thereof to produce cloned transgenic and chimeric ungulates
GB9417831D0 (en) * 1994-09-05 1994-10-26 Biotech & Biolog Scien Res Biological manipulation
FR2726003B1 (fr) * 1994-10-21 2002-10-18 Agronomique Inst Nat Rech Milieu de culture de cellules embryonnaires totipotentes aviaires, procede de culture de ces cellules, et cellules embryonnaires totipotentes aviaires
AU1274797A (en) * 1995-11-29 1997-06-19 Utah State University Establishment, maintenance, and transfection of totipotent embryonic stem cells from the embryos of domestic animals
AU721375B2 (en) * 1996-01-09 2000-06-29 Regents Of The University Of California, The Porcine embryonic stem-like cells, methods of making and using the cells to produce transgenic pigs
US5945577A (en) * 1997-01-10 1999-08-31 University Of Massachusetts As Represented By Its Amherst Campus Cloning using donor nuclei from proliferating somatic cells
ATE209423T1 (de) * 1997-03-14 2001-12-15 Cselt Centro Studi Lab Telecom Schaltung zur bewegungsschätzung in codierern für digitalisierte videosequenzen

Also Published As

Publication number Publication date
BR9808192A (pt) 2000-10-24
NZ337495A (en) 2001-06-29
WO1998039416A1 (en) 1998-09-11
AU745334B2 (en) 2002-03-21
JP2002512510A (ja) 2002-04-23
AU6688098A (en) 1998-09-22
EP0973871A1 (en) 2000-01-26

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued