CA2257803A1 - Non immunosuppressive antifungal rapalogs - Google Patents

Non immunosuppressive antifungal rapalogs

Info

Publication number
CA2257803A1
CA2257803A1 CA002257803A CA2257803A CA2257803A1 CA 2257803 A1 CA2257803 A1 CA 2257803A1 CA 002257803 A CA002257803 A CA 002257803A CA 2257803 A CA2257803 A CA 2257803A CA 2257803 A1 CA2257803 A1 CA 2257803A1
Authority
CA
Canada
Prior art keywords
immunosuppressive antifungal
non immunosuppressive
rapalogs
antifungal rapalogs
rapamycin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002257803A
Other languages
French (fr)
Other versions
CA2257803C (en
Inventor
Dennis A. Holt
Terence P. Keenan
Timothy P. Clackson
Leonard Rozamus
Wu Yang
Michael Z. Gilman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ariad Pharmaceuticals Inc
Original Assignee
Ariad Pharmaceuticals, Inc.
Dennis A. Holt
Terence P. Keenan
Timothy P. Clackson
Leonard Rozamus
Wu Yang
Michael Z. Gilman
Ariad Gene Therapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ariad Pharmaceuticals, Inc., Dennis A. Holt, Terence P. Keenan, Timothy P. Clackson, Leonard Rozamus, Wu Yang, Michael Z. Gilman, Ariad Gene Therapeutics, Inc. filed Critical Ariad Pharmaceuticals, Inc.
Priority claimed from PCT/US1997/012584 external-priority patent/WO1998002441A2/en
Publication of CA2257803A1 publication Critical patent/CA2257803A1/en
Application granted granted Critical
Publication of CA2257803C publication Critical patent/CA2257803C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

This invention concerns derivatives of rapamycin and their antifungal uses.
Also disclosed are materials and methods relevant to the identification of non-immunosuppressive antifungal rapamycin derivatives.
CA002257803A 1996-07-12 1997-07-14 Non immunosuppressive antifungal rapalogs Expired - Lifetime CA2257803C (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US2162496P 1996-07-12 1996-07-12
US60/021,624 1996-07-12
US4830797P 1997-05-30 1997-05-30
US60/048,307 1997-05-30
US5035397P 1997-06-20 1997-06-20
US60/050,353 1997-06-20
PCT/US1997/012584 WO1998002441A2 (en) 1996-07-12 1997-07-14 Non immunosuppressive antifungal rapalogs

Publications (2)

Publication Number Publication Date
CA2257803A1 true CA2257803A1 (en) 1998-01-22
CA2257803C CA2257803C (en) 2008-12-02

Family

ID=27361689

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002257803A Expired - Lifetime CA2257803C (en) 1996-07-12 1997-07-14 Non immunosuppressive antifungal rapalogs

Country Status (2)

Country Link
JP (1) JP2002514165A (en)
CA (1) CA2257803C (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112057425A (en) * 2020-09-30 2020-12-11 严鹏科 Rapamycin preparation and preparation method thereof
US11819476B2 (en) 2019-12-05 2023-11-21 Janssen Pharmaceutica Nv Rapamycin analogs and uses thereof
US11944605B2 (en) 2018-06-15 2024-04-02 Janssen Pharmaceutica Nv Rapamycin analogs and uses thereof

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006067862A1 (en) * 2004-12-22 2006-06-29 The Kitasato Institute Active substances k03-0132 and method of producing the same
WO2014115487A1 (en) 2013-01-28 2014-07-31 Pola Pharma Inc. Pharmaceutical composition for diseases caused by pathogenic microorganisms such as aspergillus
WO2014185542A1 (en) 2013-05-17 2014-11-20 Pola Pharma Inc. Pharmaceutical composition for treating vaginitis or pneumonia
KR20210105397A (en) * 2018-12-18 2021-08-26 노파르티스 아게 Rapamycin derivatives
KR20210142689A (en) 2019-03-26 2021-11-25 노파르티스 아게 Rapamycin derivatives containing isothiazolidine 1,1-dioxide and 1,4-butane sultone and uses thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11944605B2 (en) 2018-06-15 2024-04-02 Janssen Pharmaceutica Nv Rapamycin analogs and uses thereof
US11819476B2 (en) 2019-12-05 2023-11-21 Janssen Pharmaceutica Nv Rapamycin analogs and uses thereof
CN112057425A (en) * 2020-09-30 2020-12-11 严鹏科 Rapamycin preparation and preparation method thereof

Also Published As

Publication number Publication date
JP2002514165A (en) 2002-05-14
CA2257803C (en) 2008-12-02

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Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20170714