CA2255855A1 - Process to eliminate haemoglobin errors during the determination of albumin - Google Patents
Process to eliminate haemoglobin errors during the determination of albuminInfo
- Publication number
- CA2255855A1 CA2255855A1 CA002255855A CA2255855A CA2255855A1 CA 2255855 A1 CA2255855 A1 CA 2255855A1 CA 002255855 A CA002255855 A CA 002255855A CA 2255855 A CA2255855 A CA 2255855A CA 2255855 A1 CA2255855 A1 CA 2255855A1
- Authority
- CA
- Canada
- Prior art keywords
- albumin
- present
- test wavelength
- haemoglobin
- eliminate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6827—Total protein determination, e.g. albumin in urine
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Peptides Or Proteins (AREA)
Abstract
The invention concerns a method for assaying albumin in a sample containing free hemoglobin by means of optical measurements using at feast two wavelengths, where (a) an adequately strong albumin measuring signal is present at a first test wavelength, (b) with respect to the second test wavelength, (i) no albumin measurement signal is present or (ii) a substantially smaller albumin measurement signal is present compared to that of the first test wavelength, and (c) a comparable strong interference signal is present in the first and in the second test wavelength, said interference signal being time-dependent and having been generated by a reaction of hemoglobin with the assay reagent used to assay the albumin.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19622091A DE19622091A1 (en) | 1996-05-31 | 1996-05-31 | Accurate measurement of albumin in solution also containing haemoglobin |
DE19622091.2 | 1996-05-31 | ||
US4799797P | 1997-05-28 | 1997-05-28 | |
US60/047,997 | 1997-05-28 | ||
PCT/EP1997/002862 WO1997045728A1 (en) | 1996-05-31 | 1997-06-02 | Process to eliminate haemoglobin errors during the determination of albumin |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2255855A1 true CA2255855A1 (en) | 1997-12-04 |
CA2255855C CA2255855C (en) | 2005-10-11 |
Family
ID=26026235
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002255855A Expired - Fee Related CA2255855C (en) | 1996-05-31 | 1997-06-02 | Process to eliminate haemoglobin errors during the determination of albumin |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0906567B1 (en) |
JP (1) | JP2000512381A (en) |
KR (1) | KR20000016035A (en) |
CN (1) | CN1214770A (en) |
AT (1) | ATE199781T1 (en) |
AU (1) | AU3171797A (en) |
CA (1) | CA2255855C (en) |
CZ (1) | CZ27198A3 (en) |
DK (1) | DK0906567T3 (en) |
ES (1) | ES2155690T3 (en) |
HU (1) | HUP9900723A2 (en) |
IL (1) | IL127276A0 (en) |
NZ (1) | NZ332629A (en) |
PL (1) | PL330221A1 (en) |
WO (1) | WO1997045728A1 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19846301A1 (en) * | 1998-10-08 | 2000-04-13 | Roche Diagnostics Gmbh | Optical assay for determining alkaline phosphatase in samples uses specified primary and secondary measurement wavelengths |
DE19846300A1 (en) | 1998-10-08 | 2000-04-13 | Roche Diagnostics Gmbh | Optical assay for determining alkaline phosphatase in samples uses a specified primary measurement wavelength in combination with a rate blank correction |
EP2657681A1 (en) * | 2012-04-26 | 2013-10-30 | Roche Diagnostics GmbH | Improvement of the sensitivity and the dynamic range of photometric assays by generating multiple calibration curves |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6350743A (en) * | 1986-08-20 | 1988-03-03 | Hitachi Ltd | Analysis of hemolyzed blood specimen |
JPH0635982B2 (en) * | 1987-01-07 | 1994-05-11 | 株式会社島津製作所 | Sensitive assay for antigen-antibody reaction |
US5284777A (en) * | 1991-03-04 | 1994-02-08 | Isolab, Inc. | Combined glycated hemoglobin and immunoturbidometric glycated albumin assay from whole blood lysate |
JPH07294519A (en) * | 1994-03-04 | 1995-11-10 | Kyoto Daiichi Kagaku:Kk | Measurement of component in urine |
DE4427492A1 (en) * | 1994-08-03 | 1996-02-08 | Boehringer Mannheim Gmbh | Method for analyzing a medical sample while avoiding interference from hemolysis |
-
1997
- 1997-06-02 CA CA002255855A patent/CA2255855C/en not_active Expired - Fee Related
- 1997-06-02 AT AT97927108T patent/ATE199781T1/en active
- 1997-06-02 CZ CZ98271A patent/CZ27198A3/en unknown
- 1997-06-02 DK DK97927108T patent/DK0906567T3/en active
- 1997-06-02 ES ES97927108T patent/ES2155690T3/en not_active Expired - Lifetime
- 1997-06-02 IL IL12727697A patent/IL127276A0/en unknown
- 1997-06-02 WO PCT/EP1997/002862 patent/WO1997045728A1/en not_active Application Discontinuation
- 1997-06-02 JP JP09541636A patent/JP2000512381A/en active Pending
- 1997-06-02 AU AU31717/97A patent/AU3171797A/en not_active Abandoned
- 1997-06-02 HU HU9900723A patent/HUP9900723A2/en unknown
- 1997-06-02 NZ NZ332629A patent/NZ332629A/en unknown
- 1997-06-02 CN CN97193424A patent/CN1214770A/en active Pending
- 1997-06-02 PL PL97330221A patent/PL330221A1/en unknown
- 1997-06-02 EP EP97927108A patent/EP0906567B1/en not_active Expired - Lifetime
- 1997-06-02 KR KR1019980709598A patent/KR20000016035A/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
PL330221A1 (en) | 1999-05-10 |
CN1214770A (en) | 1999-04-21 |
NZ332629A (en) | 1999-11-29 |
KR20000016035A (en) | 2000-03-25 |
WO1997045728A1 (en) | 1997-12-04 |
CA2255855C (en) | 2005-10-11 |
DK0906567T3 (en) | 2001-04-17 |
JP2000512381A (en) | 2000-09-19 |
IL127276A0 (en) | 1999-09-22 |
EP0906567A1 (en) | 1999-04-07 |
ES2155690T3 (en) | 2001-05-16 |
AU3171797A (en) | 1998-01-05 |
HUP9900723A2 (en) | 1999-07-28 |
EP0906567B1 (en) | 2001-03-14 |
CZ27198A3 (en) | 1998-07-15 |
ATE199781T1 (en) | 2001-03-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |
Effective date: 20140603 |