CA2237641A1 - Recepteurs du facteur neurotrophique derive de lignees de cellules gliales - Google Patents

Recepteurs du facteur neurotrophique derive de lignees de cellules gliales Download PDF

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Publication number
CA2237641A1
CA2237641A1 CA002237641A CA2237641A CA2237641A1 CA 2237641 A1 CA2237641 A1 CA 2237641A1 CA 002237641 A CA002237641 A CA 002237641A CA 2237641 A CA2237641 A CA 2237641A CA 2237641 A1 CA2237641 A1 CA 2237641A1
Authority
CA
Canada
Prior art keywords
gdnf
cells
ret
compounds
receptors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002237641A
Other languages
English (en)
Inventor
Urmas Arumae
Carlos Ibanez
Mart Saarma
Hannu Sariola
Petro Suvanto
Miles Trupp
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Individual
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Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Individual filed Critical Individual
Publication of CA2237641A1 publication Critical patent/CA2237641A1/fr
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

L'invention concerne des récepteurs du factor neurotrophique dérivé de lignées de cellules gliales (GDNF), leur expression cellulaire, leur isolement et leur caractérisation biochimique. Le récepteur c-RET est présenté comme un récepteur de GDNF. Des récepteurs nouveaux supplémentaires sont décrits ainsi que la préparation d'anticorps monoclonaux dirigés contre GDNF.
CA002237641A 1995-11-13 1996-11-13 Recepteurs du facteur neurotrophique derive de lignees de cellules gliales Abandoned CA2237641A1 (fr)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US661995P 1995-11-13 1995-11-13
US1576796P 1996-04-16 1996-04-16
US2196596P 1996-06-27 1996-06-27
US2063896P 1996-06-27 1996-06-27
US2063996P 1996-06-27 1996-06-27
US60/021,965 1996-06-27
US60/020,638 1996-06-27
US60/020,639 1996-06-27
US60/015,767 1996-06-27
US60/006,619 1996-06-27

Publications (1)

Publication Number Publication Date
CA2237641A1 true CA2237641A1 (fr) 1997-05-22

Family

ID=27533181

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002237641A Abandoned CA2237641A1 (fr) 1995-11-13 1996-11-13 Recepteurs du facteur neurotrophique derive de lignees de cellules gliales

Country Status (8)

Country Link
EP (1) EP0879247A4 (fr)
JP (1) JP2000501924A (fr)
KR (1) KR19990067508A (fr)
AU (1) AU718979B2 (fr)
CA (1) CA2237641A1 (fr)
NO (1) NO982141L (fr)
NZ (1) NZ324511A (fr)
WO (1) WO1997018240A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1163509C (zh) * 1996-05-08 2004-08-25 拜奥根有限公司 刺激神经和肾生长的RET配体(RetL)
US6677135B1 (en) 1996-05-08 2004-01-13 Biogen, Inc. Ret ligand (RetL) for stimulating neutral and renal growth
WO2000020867A1 (fr) * 1998-10-01 2000-04-13 Alexey Vladimirovich Titievsky Nouvelle voie de signalisation independante de ret pour gdnf
US6905817B1 (en) 1998-10-01 2005-06-14 Licestia Ltd. Ret-independent signaling pathway for GDNF
FI20000403A0 (fi) * 2000-02-22 2000-02-22 Hannu Sariola GDNF perhesukuisten yhdisteiden käyttö kivessyövän hoitoon tarkoitettujen tuotteiden valmistamiseksi
IL261666B1 (en) 2016-03-31 2024-05-01 Ngm Biopharmaceuticals Inc Related proteins and methods of using them

Also Published As

Publication number Publication date
NO982141D0 (no) 1998-05-12
AU1158897A (en) 1997-06-05
AU718979B2 (en) 2000-05-04
EP0879247A1 (fr) 1998-11-25
KR19990067508A (ko) 1999-08-25
EP0879247A4 (fr) 2002-01-30
NZ324511A (en) 1999-09-29
WO1997018240A1 (fr) 1997-05-22
JP2000501924A (ja) 2000-02-22
NO982141L (no) 1998-07-13

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued