CA2221616A1 - Hibef51, recepteur de proteines g humaines - Google Patents
Hibef51, recepteur de proteines g humaines Download PDFInfo
- Publication number
- CA2221616A1 CA2221616A1 CA002221616A CA2221616A CA2221616A1 CA 2221616 A1 CA2221616 A1 CA 2221616A1 CA 002221616 A CA002221616 A CA 002221616A CA 2221616 A CA2221616 A CA 2221616A CA 2221616 A1 CA2221616 A1 CA 2221616A1
- Authority
- CA
- Canada
- Prior art keywords
- polypeptide
- receptor
- compound
- polynucleotide
- polypeptides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
La présente invention concerne des polypeptides récepteurs couplés à des protéines G humaines et l'ADN (ARN) codant de tels polypeptides, ainsi qu'une procédure de production de ces polypeptides par techniques de recombinaison. Elle concerne également des procédés d'utilisation desdits polypeptides pour l'identification d'antagonistes et d'agonistes à ces polypeptides ainsi que des procédés d'application thérapeutique des agonistes et des antagonistes dans le traitement, respectivement, de la sous-expression et de la surexpression des polypeptides récepteurs. L'invention a en outre pour objet des méthodes de diagnostic permettant de détecter une mutation dans les séquences d'acides nucléiques des récepteurs, de même qu'un niveau de la forme soluble des récepteurs dans un échantillon tiré d'un hôte.
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1995/007225 WO1996039441A1 (fr) | 1995-06-06 | 1995-06-06 | Hibef51, recepteur de proteines g humaines |
AU26997/95A AU2699795A (en) | 1995-06-06 | 1995-06-06 | Human g-protein receptor hibef51 |
EP95922244A EP0871668A4 (fr) | 1995-06-06 | 1995-06-06 | Hibef51, recepteur de proteines g humaines |
CA002221616A CA2221616A1 (fr) | 1995-06-06 | 1995-06-06 | Hibef51, recepteur de proteines g humaines |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1995/007225 WO1996039441A1 (fr) | 1995-06-06 | 1995-06-06 | Hibef51, recepteur de proteines g humaines |
CA002221616A CA2221616A1 (fr) | 1995-06-06 | 1995-06-06 | Hibef51, recepteur de proteines g humaines |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2221616A1 true CA2221616A1 (fr) | 1996-12-12 |
Family
ID=25679843
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002221616A Abandoned CA2221616A1 (fr) | 1995-06-06 | 1995-06-06 | Hibef51, recepteur de proteines g humaines |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0871668A4 (fr) |
AU (1) | AU2699795A (fr) |
CA (1) | CA2221616A1 (fr) |
WO (1) | WO1996039441A1 (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6221627B1 (en) | 1997-02-24 | 2001-04-24 | Smithkline Beecham Corporation | cDNA clone HDPB130 that encodes a novel human 7-transmembrane receptor |
GB9725462D0 (en) * | 1997-12-01 | 1998-01-28 | Smithkline Beecham Plc | Novel method |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5262529A (en) * | 1990-01-24 | 1993-11-16 | President And Fellows Of Harvard College | Diagnosis of hereditary retinal degenerative diseases |
US5462856A (en) * | 1990-07-19 | 1995-10-31 | Bunsen Rush Laboratories, Inc. | Methods for identifying chemicals that act as agonists or antagonists for receptors and other proteins involved in signal transduction via pathways that utilize G-proteins |
JPH06511386A (ja) * | 1991-10-01 | 1994-12-22 | アメリカ合衆国 | リガンドおよびリガンドのアンタゴニストを同定する方法 |
US5508384A (en) * | 1992-09-10 | 1996-04-16 | New York University | Polypeptide derived from a popamine receptor, and compositions and methods thereof |
IT1255697B (it) * | 1992-09-29 | 1995-11-10 | Enichem Spa | Metodo per l'espressione nel lievito schizosaccharomyces pombe di recettori del sistema nervoso umano |
-
1995
- 1995-06-06 CA CA002221616A patent/CA2221616A1/fr not_active Abandoned
- 1995-06-06 WO PCT/US1995/007225 patent/WO1996039441A1/fr not_active Application Discontinuation
- 1995-06-06 AU AU26997/95A patent/AU2699795A/en not_active Abandoned
- 1995-06-06 EP EP95922244A patent/EP0871668A4/fr not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
AU2699795A (en) | 1996-12-24 |
EP0871668A4 (fr) | 2000-01-05 |
WO1996039441A1 (fr) | 1996-12-12 |
EP0871668A1 (fr) | 1998-10-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Dead |