CA2216990A1 - Recepteur hdgnr10 humain de la proteine g chemokine - Google Patents

Recepteur hdgnr10 humain de la proteine g chemokine Download PDF

Info

Publication number
CA2216990A1
CA2216990A1 CA002216990A CA2216990A CA2216990A1 CA 2216990 A1 CA2216990 A1 CA 2216990A1 CA 002216990 A CA002216990 A CA 002216990A CA 2216990 A CA2216990 A CA 2216990A CA 2216990 A1 CA2216990 A1 CA 2216990A1
Authority
CA
Canada
Prior art keywords
polypeptide
receptor
compound
dna
polynucleotide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002216990A
Other languages
English (en)
Inventor
Steven M. Ruben
Yi Li
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Human Genome Sciences Inc
Original Assignee
Human Genome Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP9500367A priority Critical patent/JPH10510719A/ja
Priority to AU26632/95A priority patent/AU2663295A/en
Priority to PCT/US1995/007173 priority patent/WO1996039437A1/fr
Priority to EP95921613A priority patent/EP0815137A4/fr
Application filed by Human Genome Sciences Inc filed Critical Human Genome Sciences Inc
Priority to CA002216990A priority patent/CA2216990A1/fr
Publication of CA2216990A1 publication Critical patent/CA2216990A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7158—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for chemokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA002216990A 1995-06-06 1997-11-27 Recepteur hdgnr10 humain de la proteine g chemokine Abandoned CA2216990A1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP9500367A JPH10510719A (ja) 1995-06-06 1995-06-06 ヒトｇタンパク質ケモカインレセプターｈｄｇｎｒ１０
AU26632/95A AU2663295A (en) 1995-06-06 1995-06-06 Human g-protein chemokine receptor hdgnr10
PCT/US1995/007173 WO1996039437A1 (fr) 1995-06-06 1995-06-06 Chemokine recepteur hdgnr10 aux proteines g humaines
EP95921613A EP0815137A4 (fr) 1995-06-06 1995-06-06 Chemokine recepteur hdgnr10 aux proteines g humaines
CA002216990A CA2216990A1 (fr) 1995-06-06 1997-11-27 Recepteur hdgnr10 humain de la proteine g chemokine

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US1995/007173 WO1996039437A1 (fr) 1995-06-06 1995-06-06 Chemokine recepteur hdgnr10 aux proteines g humaines
CA002216990A CA2216990A1 (fr) 1995-06-06 1997-11-27 Recepteur hdgnr10 humain de la proteine g chemokine

Publications (1)

Publication Number Publication Date
CA2216990A1 true CA2216990A1 (fr) 1997-12-27

Family

ID=25679666

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002216990A Abandoned CA2216990A1 (fr) 1995-06-06 1997-11-27 Recepteur hdgnr10 humain de la proteine g chemokine

Country Status (5)

Country Link
EP (1) EP0815137A4 (fr)
JP (1) JPH10510719A (fr)
AU (1) AU2663295A (fr)
CA (1) CA2216990A1 (fr)
WO (1) WO1996039437A1 (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7122185B2 (en) 2002-02-22 2006-10-17 Progenics Pharmaceuticals, Inc. Anti-CCR5 antibody
US7345153B2 (en) 1996-01-17 2008-03-18 Progenics Pharmaceuticals, Inc. Compounds capable of inhibiting HIV-1 infection
US7858298B1 (en) 1996-04-01 2010-12-28 Progenics Pharmaceuticals Inc. Methods of inhibiting human immunodeficiency virus type 1 (HIV-1) infection through the administration of CCR5 chemokine receptor antagonists
US7862994B2 (en) 1995-06-07 2011-01-04 Progenics Pharmaceuticals Inc. Methods for inhibiting HIV-1 envelope glycoprotein-medicated membrane fusion
US8821877B2 (en) 2005-07-22 2014-09-02 Cytodyn Inc. Methods for inhibiting HIV-1 replication involving the administration of an anti-CCR5 receptor monoclonal antibody and small molecule CCR5 receptor antagonist

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6025154A (en) 1995-06-06 2000-02-15 Human Genome Sciences, Inc. Polynucleotides encoding human G-protein chemokine receptor HDGNR10
US6743594B1 (en) 1995-06-06 2004-06-01 Human Genome Sciences, Inc. Methods of screening using human G-protein chemokine receptor HDGNR10 (CCR5)
US6265184B1 (en) 1995-12-20 2001-07-24 Icos Corporation Polynucleotides encoding chemokine receptor 88C
DK0883687T3 (da) * 1996-03-01 2005-03-07 Euroscreen Sa C-C CKR-5, CC-chemokinreceptor, derivater deraf og anvendelse deraf
WO1997041225A2 (fr) * 1996-04-26 1997-11-06 Incyte Pharmaceuticals, Inc. Recepteurs mixtes mammaliens de lymphocytes et de chimoquine
EP0975749A2 (fr) 1996-05-28 2000-02-02 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Recepteur 5 de cc chemokine, anticorps diriges contre ce dernier et animaux transgeniques
EP0956044A4 (fr) * 1996-06-14 2005-01-05 Progenics Pharm Inc Utilisations d'un recepteur de la chemokine dans l'inhibition de l'infection par le vih-1
US5928881A (en) * 1996-07-11 1999-07-27 Smithkline Beecham Corporation Method of identifying agonists and antagonist for CC-CKR5 receptor
US6388055B1 (en) 1996-10-03 2002-05-14 Smithkline Beecham Corporation Mouse CC-CKR5 receptor polypeptide
US6528625B1 (en) 1996-10-28 2003-03-04 Millennium Pharmaceuticals, Inc. Anti-CCR5 antibodies and kits comprising same
US6153431A (en) * 1997-05-30 2000-11-28 Fond Mondiale Rech & Prev Sida Human immunodeficiency virus co-receptor variants associated with resistance to virus infection
US6204024B1 (en) 1997-09-12 2001-03-20 Akzo Nobel N.V. CCR5 RNA transcription based amplification assay
US6383746B1 (en) 1997-10-23 2002-05-07 The United States Of America As Represented By The Department Of Health And Human Services Functional promoter for CCR5
US6287805B1 (en) 1998-03-20 2001-09-11 Millennium Pharmaceuticals, Inc. Nucleic acid molecules of the protein-coupled heptahelical receptor superfamily and uses therefor
AU2001243145A1 (en) * 2000-02-09 2001-08-20 Human Genome Sciences, Inc. Human g-protein chemokine receptor (ccr5) hdgnr10
CA2404411A1 (fr) * 2000-03-27 2001-10-04 Pe Corporation (Ny) Recepteurs couples aux proteines g humaines isolees, molecules d'acides nucleiques codant les proteines gpcr humaines, et utilisations correspondantes
US7138119B2 (en) 2000-09-15 2006-11-21 Progenics Pharmaceuticals, Inc. Compositions and methods for inhibition of HIV-1 infection
US7175988B2 (en) 2001-02-09 2007-02-13 Human Genome Sciences, Inc. Human G-protein Chemokine Receptor (CCR5) HDGNR10
US7393934B2 (en) 2001-12-21 2008-07-01 Human Genome Sciences, Inc. Human G-protein chemokine receptor (CCR5) HDGNR10
WO2005105841A2 (fr) 2004-03-12 2005-11-10 Human Genome Sciences, Inc. Récepteur humain (ccr5) hdgnr10 de chimiokine de la protéine g

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6132987A (en) * 1994-01-13 2000-10-17 The Regents Of The University Of California Recombinant mammalian monocyte chemotactic protein-1 (MCP-1) receptors (MCP-1R, CCR-2)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7862994B2 (en) 1995-06-07 2011-01-04 Progenics Pharmaceuticals Inc. Methods for inhibiting HIV-1 envelope glycoprotein-medicated membrane fusion
US7901685B2 (en) 1995-06-07 2011-03-08 Progenics Pharmaceuticals Inc. Methods for assaying inhibition of HIV-1 envelope glycoprotein-mediated membrane fusion
US7345153B2 (en) 1996-01-17 2008-03-18 Progenics Pharmaceuticals, Inc. Compounds capable of inhibiting HIV-1 infection
US7858298B1 (en) 1996-04-01 2010-12-28 Progenics Pharmaceuticals Inc. Methods of inhibiting human immunodeficiency virus type 1 (HIV-1) infection through the administration of CCR5 chemokine receptor antagonists
US7935797B2 (en) 1996-04-01 2011-05-03 Progenics Pharmaceuticals Inc. CCR5 chemokine receptor-specific monoclonal antibodies capable of inhibiting HIV-1 cell fusion
US7122185B2 (en) 2002-02-22 2006-10-17 Progenics Pharmaceuticals, Inc. Anti-CCR5 antibody
US8821877B2 (en) 2005-07-22 2014-09-02 Cytodyn Inc. Methods for inhibiting HIV-1 replication involving the administration of an anti-CCR5 receptor monoclonal antibody and small molecule CCR5 receptor antagonist

Also Published As

Publication number Publication date
AU2663295A (en) 1996-12-24
JPH10510719A (ja) 1998-10-20
EP0815137A4 (fr) 1998-08-05
EP0815137A1 (fr) 1998-01-07
WO1996039437A1 (fr) 1996-12-12

Similar Documents

Publication Publication Date Title
US6511826B2 (en) Polynucleotides encoding human G-protein chemokine receptor (CCR5) HDGNR10
US6743594B1 (en) Methods of screening using human G-protein chemokine receptor HDGNR10 (CCR5)
US20110201030A1 (en) Human G-Protein Chemokine Receptor (CCR5) HDGNR10
CA2216990A1 (fr) Recepteur hdgnr10 humain de la proteine g chemokine
US5776729A (en) Human G-protein receptor HGBER32
US20020150980A1 (en) G-protein coupled receptor
US5861272A (en) C5A receptor
US20050266527A1 (en) Human G-protein receptor HIBEF51
US20060148708A1 (en) C5a receptor
AU714642B2 (en) G-protein receptor HTNAD29
EP0886643A1 (fr) Recepteur hsatu68 de la chemokine de la proteine g humaine
EP1149582A2 (fr) Récepteur humain de Chemokine aux protéines G:HDGNR10 (récepteur CCR5). Ses utilisations.
EP1148126A2 (fr) Chemokine récepteur humain HDGNR aux protéines G (Récepteur CCR5)
US20050123998A1 (en) C5a receptor
US20050059114A1 (en) G-protein receptor HTNAD29
US20060014243A1 (en) Human G-protein chemokine receptor HSATU68
CA2224094A1 (fr) Recepteur d'amines humaines
AU760468B2 (en) G-protein receptor HTNAD29
WO1996039441A1 (fr) Hibef51, recepteur de proteines g humaines
CA2216912A1 (fr) Recepteur hdgnr10 de chimiokine de la proteine g humaine
AU2003235001A1 (en) G-Protein Receptor HTNAD29
JP2007130021A (ja) ヒトｇタンパク質ケモカインレセプターｈｄｇｎｒ１０

Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead