CA2216990A1 - Recepteur hdgnr10 humain de la proteine g chemokine - Google Patents
Recepteur hdgnr10 humain de la proteine g chemokine Download PDFInfo
- Publication number
- CA2216990A1 CA2216990A1 CA002216990A CA2216990A CA2216990A1 CA 2216990 A1 CA2216990 A1 CA 2216990A1 CA 002216990 A CA002216990 A CA 002216990A CA 2216990 A CA2216990 A CA 2216990A CA 2216990 A1 CA2216990 A1 CA 2216990A1
- Authority
- CA
- Canada
- Prior art keywords
- polypeptide
- receptor
- compound
- dna
- polynucleotide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7158—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for chemokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9500367A JPH10510719A (ja) | 1995-06-06 | 1995-06-06 | ヒトgタンパク質ケモカインレセプターhdgnr10 |
AU26632/95A AU2663295A (en) | 1995-06-06 | 1995-06-06 | Human g-protein chemokine receptor hdgnr10 |
PCT/US1995/007173 WO1996039437A1 (fr) | 1995-06-06 | 1995-06-06 | Chemokine recepteur hdgnr10 aux proteines g humaines |
EP95921613A EP0815137A4 (fr) | 1995-06-06 | 1995-06-06 | Chemokine recepteur hdgnr10 aux proteines g humaines |
CA002216990A CA2216990A1 (fr) | 1995-06-06 | 1997-11-27 | Recepteur hdgnr10 humain de la proteine g chemokine |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1995/007173 WO1996039437A1 (fr) | 1995-06-06 | 1995-06-06 | Chemokine recepteur hdgnr10 aux proteines g humaines |
CA002216990A CA2216990A1 (fr) | 1995-06-06 | 1997-11-27 | Recepteur hdgnr10 humain de la proteine g chemokine |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2216990A1 true CA2216990A1 (fr) | 1997-12-27 |
Family
ID=25679666
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002216990A Abandoned CA2216990A1 (fr) | 1995-06-06 | 1997-11-27 | Recepteur hdgnr10 humain de la proteine g chemokine |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0815137A4 (fr) |
JP (1) | JPH10510719A (fr) |
AU (1) | AU2663295A (fr) |
CA (1) | CA2216990A1 (fr) |
WO (1) | WO1996039437A1 (fr) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7122185B2 (en) | 2002-02-22 | 2006-10-17 | Progenics Pharmaceuticals, Inc. | Anti-CCR5 antibody |
US7345153B2 (en) | 1996-01-17 | 2008-03-18 | Progenics Pharmaceuticals, Inc. | Compounds capable of inhibiting HIV-1 infection |
US7858298B1 (en) | 1996-04-01 | 2010-12-28 | Progenics Pharmaceuticals Inc. | Methods of inhibiting human immunodeficiency virus type 1 (HIV-1) infection through the administration of CCR5 chemokine receptor antagonists |
US7862994B2 (en) | 1995-06-07 | 2011-01-04 | Progenics Pharmaceuticals Inc. | Methods for inhibiting HIV-1 envelope glycoprotein-medicated membrane fusion |
US8821877B2 (en) | 2005-07-22 | 2014-09-02 | Cytodyn Inc. | Methods for inhibiting HIV-1 replication involving the administration of an anti-CCR5 receptor monoclonal antibody and small molecule CCR5 receptor antagonist |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6025154A (en) | 1995-06-06 | 2000-02-15 | Human Genome Sciences, Inc. | Polynucleotides encoding human G-protein chemokine receptor HDGNR10 |
US6743594B1 (en) | 1995-06-06 | 2004-06-01 | Human Genome Sciences, Inc. | Methods of screening using human G-protein chemokine receptor HDGNR10 (CCR5) |
US6265184B1 (en) | 1995-12-20 | 2001-07-24 | Icos Corporation | Polynucleotides encoding chemokine receptor 88C |
DK0883687T3 (da) * | 1996-03-01 | 2005-03-07 | Euroscreen Sa | C-C CKR-5, CC-chemokinreceptor, derivater deraf og anvendelse deraf |
WO1997041225A2 (fr) * | 1996-04-26 | 1997-11-06 | Incyte Pharmaceuticals, Inc. | Recepteurs mixtes mammaliens de lymphocytes et de chimoquine |
EP0975749A2 (fr) | 1996-05-28 | 2000-02-02 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Recepteur 5 de cc chemokine, anticorps diriges contre ce dernier et animaux transgeniques |
EP0956044A4 (fr) * | 1996-06-14 | 2005-01-05 | Progenics Pharm Inc | Utilisations d'un recepteur de la chemokine dans l'inhibition de l'infection par le vih-1 |
US5928881A (en) * | 1996-07-11 | 1999-07-27 | Smithkline Beecham Corporation | Method of identifying agonists and antagonist for CC-CKR5 receptor |
US6388055B1 (en) | 1996-10-03 | 2002-05-14 | Smithkline Beecham Corporation | Mouse CC-CKR5 receptor polypeptide |
US6528625B1 (en) | 1996-10-28 | 2003-03-04 | Millennium Pharmaceuticals, Inc. | Anti-CCR5 antibodies and kits comprising same |
US6153431A (en) * | 1997-05-30 | 2000-11-28 | Fond Mondiale Rech & Prev Sida | Human immunodeficiency virus co-receptor variants associated with resistance to virus infection |
US6204024B1 (en) | 1997-09-12 | 2001-03-20 | Akzo Nobel N.V. | CCR5 RNA transcription based amplification assay |
US6383746B1 (en) | 1997-10-23 | 2002-05-07 | The United States Of America As Represented By The Department Of Health And Human Services | Functional promoter for CCR5 |
US6287805B1 (en) | 1998-03-20 | 2001-09-11 | Millennium Pharmaceuticals, Inc. | Nucleic acid molecules of the protein-coupled heptahelical receptor superfamily and uses therefor |
AU2001243145A1 (en) * | 2000-02-09 | 2001-08-20 | Human Genome Sciences, Inc. | Human g-protein chemokine receptor (ccr5) hdgnr10 |
CA2404411A1 (fr) * | 2000-03-27 | 2001-10-04 | Pe Corporation (Ny) | Recepteurs couples aux proteines g humaines isolees, molecules d'acides nucleiques codant les proteines gpcr humaines, et utilisations correspondantes |
US7138119B2 (en) | 2000-09-15 | 2006-11-21 | Progenics Pharmaceuticals, Inc. | Compositions and methods for inhibition of HIV-1 infection |
US7175988B2 (en) | 2001-02-09 | 2007-02-13 | Human Genome Sciences, Inc. | Human G-protein Chemokine Receptor (CCR5) HDGNR10 |
US7393934B2 (en) | 2001-12-21 | 2008-07-01 | Human Genome Sciences, Inc. | Human G-protein chemokine receptor (CCR5) HDGNR10 |
WO2005105841A2 (fr) | 2004-03-12 | 2005-11-10 | Human Genome Sciences, Inc. | Récepteur humain (ccr5) hdgnr10 de chimiokine de la protéine g |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6132987A (en) * | 1994-01-13 | 2000-10-17 | The Regents Of The University Of California | Recombinant mammalian monocyte chemotactic protein-1 (MCP-1) receptors (MCP-1R, CCR-2) |
-
1995
- 1995-06-06 EP EP95921613A patent/EP0815137A4/fr not_active Withdrawn
- 1995-06-06 AU AU26632/95A patent/AU2663295A/en not_active Abandoned
- 1995-06-06 JP JP9500367A patent/JPH10510719A/ja not_active Withdrawn
- 1995-06-06 WO PCT/US1995/007173 patent/WO1996039437A1/fr not_active Application Discontinuation
-
1997
- 1997-11-27 CA CA002216990A patent/CA2216990A1/fr not_active Abandoned
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7862994B2 (en) | 1995-06-07 | 2011-01-04 | Progenics Pharmaceuticals Inc. | Methods for inhibiting HIV-1 envelope glycoprotein-medicated membrane fusion |
US7901685B2 (en) | 1995-06-07 | 2011-03-08 | Progenics Pharmaceuticals Inc. | Methods for assaying inhibition of HIV-1 envelope glycoprotein-mediated membrane fusion |
US7345153B2 (en) | 1996-01-17 | 2008-03-18 | Progenics Pharmaceuticals, Inc. | Compounds capable of inhibiting HIV-1 infection |
US7858298B1 (en) | 1996-04-01 | 2010-12-28 | Progenics Pharmaceuticals Inc. | Methods of inhibiting human immunodeficiency virus type 1 (HIV-1) infection through the administration of CCR5 chemokine receptor antagonists |
US7935797B2 (en) | 1996-04-01 | 2011-05-03 | Progenics Pharmaceuticals Inc. | CCR5 chemokine receptor-specific monoclonal antibodies capable of inhibiting HIV-1 cell fusion |
US7122185B2 (en) | 2002-02-22 | 2006-10-17 | Progenics Pharmaceuticals, Inc. | Anti-CCR5 antibody |
US8821877B2 (en) | 2005-07-22 | 2014-09-02 | Cytodyn Inc. | Methods for inhibiting HIV-1 replication involving the administration of an anti-CCR5 receptor monoclonal antibody and small molecule CCR5 receptor antagonist |
Also Published As
Publication number | Publication date |
---|---|
AU2663295A (en) | 1996-12-24 |
JPH10510719A (ja) | 1998-10-20 |
EP0815137A4 (fr) | 1998-08-05 |
EP0815137A1 (fr) | 1998-01-07 |
WO1996039437A1 (fr) | 1996-12-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Dead |