CA2215986A1 - Particle separation apparatus and method - Google Patents

Particle separation apparatus and method

Info

Publication number
CA2215986A1
CA2215986A1 CA002215986A CA2215986A CA2215986A1 CA 2215986 A1 CA2215986 A1 CA 2215986A1 CA 002215986 A CA002215986 A CA 002215986A CA 2215986 A CA2215986 A CA 2215986A CA 2215986 A1 CA2215986 A1 CA 2215986A1
Authority
CA
Canada
Prior art keywords
fluid chamber
particles
inlet
chamber
particle separation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002215986A
Other languages
French (fr)
Other versions
CA2215986C (en
Inventor
Dennis Hlavinka
Frank Corbin
Robert Langley
Linda A. Taylor
John C. Walker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Terumo BCT Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/423,578 external-priority patent/US5674173A/en
Application filed by Individual filed Critical Individual
Priority claimed from PCT/US1996/005505 external-priority patent/WO1996033023A1/en
Publication of CA2215986A1 publication Critical patent/CA2215986A1/en
Application granted granted Critical
Publication of CA2215986C publication Critical patent/CA2215986C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0209—Multiple bag systems for separating or storing blood components
    • A61M1/0218—Multiple bag systems for separating or storing blood components with filters
    • A61M1/0227—Multiple bag systems for separating or storing blood components with filters and means for securing the filter against damage, e.g. during centrifugation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0209—Multiple bag systems for separating or storing blood components
    • A61M1/0236—Multiple bag systems for separating or storing blood components with sampling means, e.g. sample bag or sampling port
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3618—Magnetic separation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/362—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits changing physical properties of target cells by binding them to added particles to facilitate their subsequent separation from other cells, e.g. immunoaffinity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3692—Washing or rinsing blood or blood constituents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A61M1/3696—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0407—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles
    • B04B5/0428—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles with flexible receptacles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/0471—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with additional elutriation separation of different particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • External Artificial Organs (AREA)
  • Centrifugal Separators (AREA)

Abstract

An apparatus and method are disclosed for filtering or separating particles.
The apparatus has a centrifuge rotor (12) rotatable about an axis of rotation. A fluid chamber (22) rotates with the rotor. A substance is supplied to the inlet (28) of the chamber. A saturated fluidized bed of first particles forms within the fluid chamber and obstructs flow of second particles through the chamber. In an embodiment of the invention, additives substances alter sedimentation velocity of the first particles to modify the filtration characteristics of the saturated fluidized bed. The fluid chamber includes a wall extending between an inlet (28) and outlet (32) to form a fluid chamber interior. The interior converges from a position of maximum cross-sectional area toward the inlet. A groove or a step may be formed on an inner surface of the fluid chamber wall to improve particle separation within the fluid chamber.
CA002215986A 1995-04-18 1996-04-18 Particle separation apparatus and method Expired - Fee Related CA2215986C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US42358395A 1995-04-18 1995-04-18
US08/423,578 1995-04-18
US08/423,583 1995-04-18
US08/423,578 US5674173A (en) 1995-04-18 1995-04-18 Apparatus for separating particles
PCT/US1996/005505 WO1996033023A1 (en) 1995-04-18 1996-04-18 Particle separation apparatus and method

Publications (2)

Publication Number Publication Date
CA2215986A1 true CA2215986A1 (en) 1996-10-24
CA2215986C CA2215986C (en) 2006-12-12

Family

ID=37561076

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002215986A Expired - Fee Related CA2215986C (en) 1995-04-18 1996-04-18 Particle separation apparatus and method

Country Status (1)

Country Link
CA (1) CA2215986C (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4302879A1 (en) * 2022-07-08 2024-01-10 Thermo Electron SAS Retaining ring for a centrifuge

Also Published As

Publication number Publication date
CA2215986C (en) 2006-12-12

Similar Documents

Publication Publication Date Title
EP1847283A3 (en) Particle separation apparatus and method
US4698156A (en) Rotating filter apparatus for separating fine particles of solids from a liquid
US5779619A (en) Centrifugal separator
KR920004041A (en) Gas Spray Centrifugal Devices
GR3000514T3 (en) Rotational particle separator
MY114997A (en) Mechanical fluid separator
CA1069096A (en) Centrifugal separator with discharge pump
CA2047314A1 (en) Method of and apparatus for pumping particulate solids
EP0586382B1 (en) Inflatable dam for a decanter centrifuge
JPS5959261A (en) Energy restoring centrifuge
EP0657197B1 (en) Filter apparatus
CA2215986A1 (en) Particle separation apparatus and method
JP4058338B2 (en) Centrifuge using sieve system and method of operating the same
US5180493A (en) Rotating hydrocyclone separator with turbulence shield
FI895486A0 (en) Separator and method for separating solids and liquids
AU656957B2 (en) Hydrocyclone separator with turbulence shield
DE3363804D1 (en) Installation and method for separating the constituents of a suspension
EP0134361A1 (en) Apparatus and method for withdrawing fluid from a zone
SE503151C2 (en) Helmantelsnäckcentrifug
WO1997040915A3 (en) Mechanical device for separation of dust particles from exhaust gases
US5330647A (en) Filter device for separating coarse components from liquid components
JP2796928B2 (en) Centrifugal fluidized bed separation method and apparatus for heterogeneous powder mixture
SU642001A1 (en) Separator for clarifying suspensions
JPH07505684A (en) Method and device for processing pulp
CA2184480A1 (en) Separator for separating particles from a slurry

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed