CA2190108C - Conjugues peptide-chelate metallique se liant a la somatostatine - Google Patents

Conjugues peptide-chelate metallique se liant a la somatostatine Download PDF

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Publication number
CA2190108C
CA2190108C CA002190108A CA2190108A CA2190108C CA 2190108 C CA2190108 C CA 2190108C CA 002190108 A CA002190108 A CA 002190108A CA 2190108 A CA2190108 A CA 2190108A CA 2190108 C CA2190108 C CA 2190108C
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CA
Canada
Prior art keywords
cyclo
amide
fyw
hcy
ch2co
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002190108A
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English (en)
Other versions
CA2190108A1 (fr
Inventor
Richard T. Dean
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CIS Bio International SA
Original Assignee
CIS Bio International SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/241,625 external-priority patent/US5783170A/en
Application filed by CIS Bio International SA filed Critical CIS Bio International SA
Publication of CA2190108A1 publication Critical patent/CA2190108A1/fr
Application granted granted Critical
Publication of CA2190108C publication Critical patent/CA2190108C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/083—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

La présente invention se rapporte à des agents diagnostiques et radiodiagnostiques, y compris des agents d'imagerie scintigraphiques radiomarqués, ainsi que des agents thérapeutiques et radiothérapeutiques. L'invention se rapporte à ces agents et à des réactifs servant à préparer ces agents, ainsi qu'à des procédés de production et d'utilisation de ces réactifs. L'invention se rapporte spécifiquement à des agents d'imagerie radiomarqués et à des agents d'imagerie marqués non radioactivement servant à former des images de sites du corps d'un mammifère, et à des réactifs permettant de préparer ces agents d'imagerie. L'invention se rapporte également à des agents thérapeutiques radiomarqués et à des agents thérapeutiques marqués non radioactivement, et à des réactifs et des procédés permettant de préparer ces agents. Les agents et le réactifs décrits comprennent un peptide de liaison spécifique, lié de manière covalente à une fraction de complexage d'ion métal. On décrit également des réactifs, des procédés et des kits permettant de préparer ces réactifs, des procédés de marquage de ces réactifs ainsi que des procédés d'utilisation de ces réactifs marqués.
CA002190108A 1994-05-12 1995-05-12 Conjugues peptide-chelate metallique se liant a la somatostatine Expired - Fee Related CA2190108C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/241,625 US5783170A (en) 1991-11-27 1994-05-12 Peptide-metal chelate conjugates
US08/241,625 1994-05-12
PCT/US1995/006034 WO1995031221A1 (fr) 1994-05-12 1995-05-12 Conjugues peptide-chelate metallique se liant a la somatostatine

Publications (2)

Publication Number Publication Date
CA2190108A1 CA2190108A1 (fr) 1995-11-23
CA2190108C true CA2190108C (fr) 2007-04-10

Family

ID=38007167

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002190108A Expired - Fee Related CA2190108C (fr) 1994-05-12 1995-05-12 Conjugues peptide-chelate metallique se liant a la somatostatine

Country Status (1)

Country Link
CA (1) CA2190108C (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115444965B (zh) * 2022-08-18 2024-03-29 南通大学 一种环肽抗菌纳米敷料及其制备方法

Also Published As

Publication number Publication date
CA2190108A1 (fr) 1995-11-23

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