CA2168205A1 - Anticorps conjugues a un analogue de biotine pour la selection positive et la liberation de cellules - Google Patents

Anticorps conjugues a un analogue de biotine pour la selection positive et la liberation de cellules

Info

Publication number
CA2168205A1
CA2168205A1 CA 2168205 CA2168205A CA2168205A1 CA 2168205 A1 CA2168205 A1 CA 2168205A1 CA 2168205 CA2168205 CA 2168205 CA 2168205 A CA2168205 A CA 2168205A CA 2168205 A1 CA2168205 A1 CA 2168205A1
Authority
CA
Canada
Prior art keywords
biotin
antibody
complex
biotin analog
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2168205
Other languages
English (en)
Inventor
Fahad A. Al-Abdaly
Yu-An Chang
Roy Guillermo
William H. Scouten
Alan K. Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter International Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2168205A1 publication Critical patent/CA2168205A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances

Abstract

L'invention concerne un conjugué stable d'une protéine de fixation des cellules cibles, et de préférence un anticorps fixé par liaison covalente à un fragment d'analogue de la biotine destiné à être utilisé dans la sélection et la libération cellulaire positives. L'invention porte également sur des procédés de sélection et de libération positives dans lesquels lesdits conjugués sont utilisés.
CA 2168205 1993-09-08 1994-09-08 Anticorps conjugues a un analogue de biotine pour la selection positive et la liberation de cellules Abandoned CA2168205A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11806893A 1993-09-08 1993-09-08
US08/118,068 1993-09-08

Publications (1)

Publication Number Publication Date
CA2168205A1 true CA2168205A1 (fr) 1995-03-16

Family

ID=22376345

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2168205 Abandoned CA2168205A1 (fr) 1993-09-08 1994-09-08 Anticorps conjugues a un analogue de biotine pour la selection positive et la liberation de cellules

Country Status (5)

Country Link
EP (1) EP0717848A1 (fr)
JP (1) JPH09502351A (fr)
AU (1) AU7832094A (fr)
CA (1) CA2168205A1 (fr)
WO (1) WO1995007466A2 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5518882A (en) * 1993-12-21 1996-05-21 Biotex Laboratories, Inc. Immunological methods of component selection and recovery
US6017719A (en) * 1994-06-14 2000-01-25 Nexell Therapeutics, Inc. Positive and positive/negative cell selection mediated by peptide release
WO1997044666A1 (fr) * 1996-05-17 1997-11-27 Cytovax Biotechnologies Inc. Procedes immunologiques de selection et d'extraction de composants
MXPA02011587A (es) * 2000-05-23 2004-07-30 Nexell Therapeutics Inc Reactivos para la seleccion de celulas y metodos de uso.
EP1429143A4 (fr) * 2001-08-22 2006-04-12 Inst Antibodies Co Ltd Procede de selection d'une molecule de liaison
US7956165B2 (en) 2003-07-24 2011-06-07 Affisink Biotechnology Ltd. Compositions and methods for purifying and crystallizing molecules of interest
WO2008140573A2 (fr) * 2006-11-15 2008-11-20 Invitrogen Dynal As Procédés pour lier de façon réversible un composé de biotine à un support
WO2015195404A1 (fr) 2014-06-20 2015-12-23 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Procédés de détection d'un analyte par le mouvement de microparticules attachées
WO2016205239A1 (fr) 2015-06-15 2016-12-22 The United States Of America, As Represented By The Secretary Department Of Health And Human Services Contraception non hormonale à leurre de sperme de mammifère basée sur l'extrémité n-terminale de la protéine zp2
AU2017345814B2 (en) 2016-10-21 2022-07-28 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Molecular nanotags
WO2018217630A1 (fr) * 2017-05-21 2018-11-29 University Of Tennessee Research Foundation Méthodes et compositions pour le ciblage de lésions tissulaires
WO2019133727A1 (fr) 2017-12-29 2019-07-04 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Ensemble de sondes universelles de virus de la grippe pour l'enrichissement d'un quelconque acide nucléique du virus de la grippe
WO2022056078A1 (fr) 2020-09-11 2022-03-17 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Dosage de détection assisté par rnase h d'arn (radar)
US20230383342A1 (en) * 2022-05-31 2023-11-30 Illumina Cambridge Limited Compositions and methods for nucleic acid sequencing

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5215927A (en) * 1986-01-30 1993-06-01 Fred Hutchinson Cancer Research Center Method for immunoselection of cells using avidin and biotin
WO1987004628A1 (fr) * 1986-01-30 1987-08-13 Fred Hutchinson Cancer Research Center Procede de selection immunologique

Also Published As

Publication number Publication date
WO1995007466A3 (fr) 1995-04-06
WO1995007466A2 (fr) 1995-03-16
AU7832094A (en) 1995-03-27
JPH09502351A (ja) 1997-03-11
EP0717848A1 (fr) 1996-06-26

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Legal Events

Date Code Title Description
FZDE Dead